Joint Report of the First International Comparison Test on Swine Lymphocyte Alloantigens (SLA)

Abstract

The first international comparison test on swine lymphocyte alloantigens (SLA) was held in Helsinki, Finland in July 1986. The results reported were based on a comparison of 157 alloantisera originating from six laboratories. The antisera were tested against a selected panel of 264 lymphocyte samples belonging to four laboratories. The most common breeds in Europe were chosen for this first comparison test (Landrace and Large White). Eighteen of the 31 previously known specificities were confirmed and a new nomenclature was established.

Postoperative intravenous infusion of donor-derived transplant acceptance-inducing cells as an adjunct immunosuppressive therapy in a porcine pulmonary allograft model

“…Animals from different breeding lines were tissue‐typed prospectively using a lymphocytotoxic assay. Subsequently, donors and recipients were mismatched for the MHC class I DC 80 and H04 haplotypes [18] and for reactivity with the MHC class I haplotyped specific monoclonal antibody 74‐11‐10. All animals received humane care in compliance with the German animal protection legislation, the ‘Principles of Laboratory Animal Care’, and the ‘Guide for the Care and Use of Laboratory Animals’ prepared by the Institute of Laboratory Animal Resources, National Research Council, and published by the National Academy Press, revised 1996.…”

Haematological Traits of Nigerian Indigenous Pig and Its Hybrid (50% Large White × 50 NIP) at Post Weaning Ages

“…It is one of the first signs or indicators of disease invasion in animal body. Lunney and Rowland (2011) [13] reported that blood immune traits against diseases could be detected early. This early detection of against diseases through the blood immune traits can be used as criteria for selection at these ages.…”

Marked genetic polymorphism of the swine steroid 21‐hydroxylase gene, and its location between the SLA class I and class II regions

“…Thirty-one unrelated pigs were tested, including one group of 12 SLA genotypic homozygotes and a second group of 19 SLA class I phenotypic homozygotes born to parents sharing phenotypically identical SLA class I haplotypes ( Table 1). The SLA nomenclature used followed the one adopted by the First International Comparison Test on Swine Lymphocyte Antigens (Renard et al 1988). In all, 15 distinct SLA fiaplotypes were studied, of which 13 were found in French Large Whites and several other breeds, one in French Landrace pigs, and one in pigs of a synthetic line (Table We also analysed 12 related pigs from two SLA class I and class I1 informative families comprising three previously described SLA recombinants (Vaiman et af.…”

“…Our routine laboratory techniques were used for SLA class I serological typing and mixed lymphocyte culture reactions (Vaiman et at. 1978;Renard et al 1988).…”