This review covers the time period of about December 1975 to November 1977. Since we depend on abstracting services in some cases, there is some time overlap with the period covered by the last review (73). The literature surveyed for this review included major analytical, chromatography, and polymer journals, as well as various abstracting services. We've included literature on size separation from soft gels ("gel filtration"), semi-rigid gels ("GPC"), and porous, inorganic column packings ("rigid gels"). And we've reviewed size separations involving small molecules as well as work restricted to macromolecules. We continue to use the common abbreviation, GPC, for gel permeation chromatography applications involving all the above areas. The more definitive "steric exclusion chromatography" is, however, still preferred nomenclature.
GENERAL REVIEWSA number of books published during this period included one or more sections on theory and use of steric exclusion chromatography (28,55,152,174,176). Several review articles also included general GPC information. Abbott (1) and Miller (129) discussed elementary operating principles and usefullness for polymer analyses. Krauss and Krauss reviewed theory and practice of both thin layer and column GPC (105). Current status of aqueous GPC was reviewed by Cooper and
The application of phase-selective cathodic stripping (PSCS) voltammetry to analyses of water-soluble mercaptans has been demonstrated using a micrometer hanging mercury drop electrode. The sensitivity limit was near 1 ppb for sodium mercaptoacetate (SMA) analysis when a 2-mln deposition interval was employed. The average deviation for six Independent experiments with 25 ppb SMA was 3.62 %. The dependence of PSCS peak currents upon mercaptan concentration, applied ac voltage magnitude, signal frequency, and dc potential scan rate was investigated. Because ac voltammetry discriminates against Irreversible electrode processes, mercaptan PSCS experiments could be performed in air-saturated electrolytes. As a result, the method appears to be suitable for analyses of volatile mercaptans when Inert gas purging to remove oxygen Is not practical.
H. L. James is a Project Leader in the Chemical Analysis section of the R&D division of the Standard Oil Company (Ohio). He is presently involved in Analytical Research and Method Development in the areas of polymers and petroleum. Recent research interests include developing liquid exclusion chromatographic methods for monitoring polymerization processes. Mr. James received his B.A. in chemistry from Syracuse University and his M.S. in polymer chemistry from the University of Akron. He is coauthor of ten scientific papers in various areas of polymer characterization, co-chairman of the Akron-Cleveland GPC/LC Discussion Group, co-editor of the ASTM Bibliography on Liquid Exclusion Chron phy, and a member of the American Chemical Society and Sigma Xi.
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