The article discusses the treatment and prevention of feed toxicosis of pigs. A composition based on montmorillonite-containing minerals is considered as a promising enterosorbent in combination with the drug vievitin in the treatment of pig dysentery. Studies have shown that the complex use of vievitin with a sorbent by giving individually in 100 ml of drinking water at doses of 5.6 (second group) and 11.1 (third group) mg/kg body weight for vievitin and 400 mg/kg body weight bodies for the sorbent provided a high therapeutic effect in the treatment of piglets suffering from dysentery. Recovery, respectively, was 90.8 and 93.8%.
This articlestudies the action and biocompatibility of the developed montmorillonite-containing preparation "Sorbent" on experimental animals with its longterm use. The local irritating effect of the "Sorbent" preparation was evaluated by its effect on the gastric mucosa of animals with experimental ulcerative pathology. The size of the most common particles in the suspension is 5-8 microns.
The experiments were carried out on white rats of the Wistar line and non-linear Hartley guinea pigs.To identify the irritating effect, the drug was administered to animals in therapeutic doses of 200 mg/kg and three times the conditionally therapeutic dose -600 mg/kg of body weight. Destructive changes in the stomachs of experimental animals were studied macroscopically. The ulcerogenic effect was evaluated by calculating the Pauls index.
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