Enterosorbent based on montmorillonite as a promising tool in the treatment and prevention of intestinal disorders in pigs

Abstract

The article discusses the treatment and prevention of feed toxicosis of pigs. A composition based on montmorillonite-containing minerals is considered as a promising enterosorbent in combination with the drug vievitin in the treatment of pig dysentery. Studies have shown that the complex use of vievitin with a sorbent by giving individually in 100 ml of drinking water at doses of 5.6 (second group) and 11.1 (third group) mg/kg body weight for vievitin and 400 mg/kg body weight bodies for the sorbent provided a high therapeutic effect in the treatment of piglets suffering from dysentery. Recovery, respectively, was 90.8 and 93.8%.

Nanostructure and thermal characteristics of silica/human serum albumin systems based on a modified nanosilica entero-vulnerosorbent

“…The creation of modern sorbents with desired properties for specific applications is associated not only with the selection of appropriate carriers, but also with the development of a method for their modification and determination of the nature of interactions between biomolecules-carrier surfaces. [20][21][22][23][24][25][26][27][28][29] It is well known that amorphous non-porous fumed silica (Aerosil, Sillard, Polysorb MP silica, nanosilica, colloidal silica, fumed oxides) is an auxiliary substance used in the production of drugs in the form of medical enterosorbents and is characterized by high sorption capacity for proteins and toxins. 19 Highly dispersed fumed oxide silica with a BET surface area S BET in the range of 270-330 m 2 g À1 and low bulk density d b in the range of 20-45 g L À1 was fabricated in the National Academy of Sciences (NAS) of Ukraine in a powder form (A300) and used as an effective medicine with sorption-detoxification properties (e.g., gastrointestinal enteroadsorbents).…”

“…The creation of modern sorbents with desired properties for specific applications is associated not only with the selection of appropriate carriers, but also with the development of a method for their modification and determination of the nature of interactions between biomolecules-carrier surfaces. 20–29…”