ObjectiveThe aim of this study was to determine the amounts of fluoride and aluminum released from different restorative materials stored in artificial saliva and double-distilled water. Material and MethodsCylindrical specimens (10 x 1 mm) were prepared from 4 different restorative materials (Kavitan Plus, Vitremer, Dyract Extra, and Surefil). For each material, 20 specimens were prepared, 10 of which were stored in 5 mL artificial saliva and 10 of which were stored in 5 mL of double-distilled water. Concentrations of fluoride and aluminum in the solutions were measured using ion chromatography. Measurements were taken daily for one week and then weekly for two additional weeks. Data were analyzed using two-way ANOVA and Duncan's multiple range tests (p<0.05). ResultsThe highest amounts of both fluoride and aluminum were released by the resin-modified glass ionomer cement Vitremer in double-distilled water (p<0.05). All materials released significantly more fluoride in double-distilled water than in artificial saliva (p<0.05). In artificial saliva, none of the materials were observed to release aluminum. ConclusionIt was concluded that storage media and method of analysis should be taken into account when the fluoride and aluminum release from dental materials is assessed.

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Homosistein, metiyonin metabolizması sırasında oluşan, proteinlerin primer yapısına girmeyen, kükürtlü bir aminoasittir 1. Vücutta vitamin B12'nin kofaktör olduğu remetilasyon ve vitamin B6'nın kofaktör olduğu transsülfürasyon yoluyla metabolize edilir 2. Homosisteinin plazma seviyesinin yükselmesi vücutta birçok zararlı etkiye yol açmaktadır. Bunlardan bazıları; serbest radikaller gibi davranarak endotel hasarı oluşturması ve bunun sonucunda da trombosit aktivasyonunun artırması, pıhtılaşma faktörlerinin modifikasyonu, trombus formasyonu gibi koagulasyonu artırıcı etkiler meydana getirmesi, biyolojik membran

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