In this study, polyphenolic curcumin is entrapped within microcomposites made of biopolymers chitosan (CS) and carboxymethyl cellulose (CMC) formulated by ionic gelation method. Here, different concentrations of two chelating agents, barium chloride and sodium tripolyphosphate, are used to make microcomposites. Thus, the synthesized microparticles were characterized by FTIR, and their surface morphology was studied by SEM. Drug encapsulation efficiency and the drug release kinetics of CS-CMC composites are also studied. The produced microcomposites were used to study antibacterial activity in vitro.
Most look into the benefits of the nanoparticles, but keeping aside the benefits; this study focuses on the impacts of nanoparticles on living systems. Improper disposal of nanoparticles into the environment is a subject of pollution or nano-pollution which in turn affects the flora and fauna in the ecosystem, particularly soil ecosystem. Thus, this study was done to understand the impacts of chemically synthesized magnetite nanoparticles on earthworm-Eudrilus eugeniae, a soil-dependent organism which acquires food and nutrition from decaying matters. The chemically synthesized magnetite nanoparticles were characterized by UV-visible spectrophotometry, Fourier transform infrared spectroscopy and field emission scanning electron microscopy. Earthworms were allowed to interact with different concentrations of synthesized nanoparticles and the effect of the nanoparticles was analysed by studying the phenotypic changes followed by histology and inductively coupled plasma optical emission spectrometry analyses.
In this study, curcumin (CUR) was encapsulated into chitosan (CS) and carboxymethyl cellulose (CMC) microparticles
using sodium tripolyphosphate (TPP) as chelator. Here, different concentrations (0.1%, 0.3% and 0.5%) of sodium
tripolyphosphate (TPP) were utilised to synthesise microparticles. Microparticles were characterized by Fourier Transform
Infra-Red Microscopy (FTIR) and Scanning Electron Microscope (SEM). All the CUR encapsulated microparticles were
analysed for their drug encapsulation efficiency and the drug release kinetics. Microparticles were studied for the invitro
controlled drug release against Pseudomonas aeruginosa.
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