The presence of cervical phIGFBP-1 is predictive of preterm delivery < 37 weeks of gestation. Our study shows that cervical detection of phIGFBP-1 by immunochromotography is a rapid and easily applicable test that highly anticipates preterm delivery in patients at risk.
A number of studies have linked high maternal serum hemoglobin (Hb) levels in pregnancy with increased incidence of adverse pregnancy outcomes, such as low birth weight and small-forgestational-age newborns, pre-term births, increased perinatal mortality, and pre-eclampsia w1x. Lao et al. identified high maternal hemoglobin at the initial prenatal visit as a risk factor for gestational diabetes mellitus (GDM) w2x.This prospective study was conducted on 253 non-diabetic Turkish women with singleton pregnancies whose serum Hb level and mean corpuscular volume (MCV) at the initial visit were )10 gydl or )80 fl, respectively. The exclusion criteria were first prenatal visit later than 14 weeks of gestation; pre-existing anemia or hemoglobinopathy, chronic disease; such as diabetes mellitus, renal or gastrointestinal disorder, hypo-or hyperthyroidism, GDM diagnosed before 28 weeks' gestation. Values signifying the 50th percentile for Hb (12.2 gydl) and ferritin (Fe) (19.7 mgyl) were established based on these data, and two sets of groups were formed based on the initial-visit findings (Hb above and below the 50th percentile; Fe
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