Diffuse optical imaging through centimeters of tissue has emerged as a powerful tool in biomedical research. However, applications in the operating theater have been limited in part due to data set requirements and computational burden. We present an approach that uses a small number of optical source-detector pairs that allows for the fast localization of arteries in the roof of the mouth and has the potential to reduce complications during oral surgery. The arteries are modeled as multiple-point absorbers, allowing localization of their complex shapes. The method is demonstrated using a printed tissue-simulating mouth phantom. Furthermore, we use the extracted position information to fabricate a custom surgical guide using 3D printing that could protect the arteries during surgery.
A programmed-defect mask consisting of both bump-and pit-type defects on the LTEM mask substrate has been successfully fabricated. It is seen that pit-type defects are less printable because they are more smoothed out by the employed MLM deposition process. Specifically, all bump-type defects print even at the smallest height split of 1.7 nm whereas pit-type defects print only at the largest depth split of 5.7 nm. At this depth, the largest nonprintable 1D and 2D defect widths are about 23 nm and 64 nm, respectively.
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