Background
Reactogenicity of coronavirus disease 2019 (COVID-19) vaccines can result in inability to work. The object of this study was to evaluate health care workers’ sick leave after COVID-19 vaccination and to compare it with sick leave due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and quarantine leave.
Methods
A multi-center cross-sectional survey was conducted at Regensburg University Medical Center and ten teaching hospitals in South-East Germany from July 28th to October 15th 2021.
Results
Of 2662 participants, 2309 (91.8%) were fully vaccinated without a history of SARS-CoV-2 infection. Sick leave after first/second vaccination occurred in 239 (10.4%) and 539 (23.3%) participants. In multivariable logistic regression, the adjusted odds ratio for sick leave after first/second vaccination compared to BNT162b2 was 2.26/3.72 for mRNA-1237 (95% confidence interval (CI) 1.28-4.01/1.99-6.96) and 27.82/0.48 for ChAdOx1-S (95% CI 19.12-40.48/0.24-0.96). The actual median sick leave was one day (interquartile range (IQR) 0-2) after any vaccination. 251 participants (9.4%) reported a history of SARS-CoV-2 infection (median sick leave 14 days, IQR 10-21), 353 (13.3%) were quarantined at least once (median quarantine leave 14 days, IQR 10-14). Sick leave due to SARS-CoV-2 infection (4642 days) and quarantine leave (4710 days) accounted for 7.7 times more loss of workforce than actual sick leave after first and second vaccination (1216 days) in all fully vaccinated participants.
Conclusions
Sick leave after COVID-19 vaccination is frequent and associated with the vaccine applied. COVID-19 vaccination should reduce the much higher proportion of loss of workforce due to SARS-CoV-2 infection and quarantine.
Die akute infektiöse Lungenerkrankung COVID-19 (Coronavirus Disease 2019) war im Dezember 2019 erstmalig in Wuhan/China, ausgelöst durch den Coronavirussubtyp SARS-CoV-2 (Severe Acute Respiratory Syndrome Corona-Virus-2), nachgewiesen worden. Die dadurch verursachte Pandemie stellt eine globale Herausforderung für die Gesundheitssysteme der betroffenen Länder dar. Tab. 1 Symptomhäufigkeiten bei COVID-19-Erkrankung COVID-19-Symptome WHO [7] 20.02.2020 55.924 Fälle (%) ECDC [1] 21.04.2020 100.233 Fälle (%)
Der Begriff "akutes Abdomen" umfasst eine Vielzahl von Erkrankungen, die häufig im Bauchraum auftreten, meist akut einsetzen und von Symptomen wie Übelkeit und Erbrechen begleitet sein können. Die Herausforderung für den Arzt besteht darin, eine ganze Reihe von vital gefährdenden Erkrankungen von weniger dringlichen Beschwerdeursachen abzugrenzen. Auch extraabdominale Differenzialdiagnosen sind in Betracht zu ziehen.
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