During the ongoing coronavirus disease (COVID‐19) pandemic, COVID‐19 vaccination is rapidly progressing in many countries of the world. Given the rapid administration of COVID‐19 vaccines, it is speculated that dermatologists also have the opportunity to experience side effects of these vaccines. Here, we report a case of unilateral lymphadenopathy associated with COVID‐19 vaccination that presented to our outpatient department of dermatology with subcutaneous nodules.
Pulmonary embolism (PE) is usually caused by thrombosis or tumor. We report the long-term survival of a patient with PE due to a leiomyosarcoma in the deep vein. A 71-year-old woman complained of dyspnea and swelling of the left lower limb. Computed tomography revealed filling defects in the pulmonary arteries and deep vein. She was diagnosed with PE caused by venous thrombosis and treated with anticoagulant therapy. Her symptoms were prolonged, and D-dimer tests remained negative. Biopsy of the substance in the deep vein revealed leiomyosarcoma. The possibility of PE caused by extravascular or intravascular tumors should be considered when a patient is negative for D-dimer.
Extramammary Paget's disease (EMPD) is a malignant neoplasm that arises in areas rich in apocrine glands. 1 Mammary Paget's disease was first described by James Paget in 1874. 2 Radcliffe Crocker reported EMPD involving the scrotum and penis in 1889, 3 and William Dubreuilh described vulvar EMPD in 1901. 4 As of now, it has been known that EMPD occurs more frequently in Asians (10 cases per million) than in Westerners (0.9 cases per million), and the most frequently affected site is the vulva, followed by perianal, scrotal, and penile skin. 5 In the clinical diagnosis of EMPD, it is often misdiagnosed as many other benign inflammatory skin diseases such as contact dermatitis, seborrheic dermatitis, eczema, and superficial fungal infections due to
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