Pada masa pandemi ini memberikan dampak yang cukup besar baik dari segi ekonomi maupun kesehatan. Di tengah kepanikan masyarakat di masa pandemi Covid-19 ini, usaha pembuatan tumbuhan obat-obatan menjadi jamu merupakan alternatif solusi. Sebagai upaya preventif, masyarakat banyak mengonsumsi jamu dan minuman kesehatan sehingga bisnis empon-empon atau ramuan rempah menjadi pilihan yang menguntungkan. Tujuan dari kegiatan ini adalah melatih ibu-ibu rumah tangga untuk dapat membuat minuman herbal dari jahe dan memasarkannya secara online. Metode pelaksanaan pengabdian adalah pihak penyelenggara merekrut ibu rumah tangga sebanyak 16 orang yang bersedia terlibat dalam program ini, diberikan pelatihan secara online memproduksi olahan jahe dan mampu melakukan pemasaran secara online. Penyelenggara melakukan evaluasi pengetahuan dan skill peserta dalam hal pengolahan jahe dan bagaimana melakukan pemasaran online. Hasil evaluasi menunjukkan ada peningkatan pengetahuan tentang pengolahan jahe dan pemasaran online sesudah dilakukan pelatihan secara online Observasi keterampilan peserta baik karena semua dapat mengolah produk jahe.
BACKGROUND: Indonesia has numerous coal resources, but the effects of environmental pollution by coal dust to human health, especially the reproductive system, are still less investigated. Chronic coal exposures during pregnancy might cause systemic and uterine inflammation that induces disturbances of spiral artery remodeling. AIM: This research was conducted to analyze the effect of coal dust exposures to uterine spiral artery remodeling and natural killer (NK) cell counts. METHODS: There were 42 female adult Rattus norvegicus rats which had been simultaneously mated after synchronization of estrous cycle used as animal subjects. The rats then divided into seven groups, those were K0 (without exposure); K1-1, K1-2, K1-3; and K2-1, K2-2, K2-3 which were exposed to 6.25 mg/m3, 12.5 mg/m3, and 25 mg/m3 dose for 1 h (K1) and 2 h (K2) per day, respectively. The rats were exposed by a dust exposure machine (NKBS-1-2010- 0.5) every morning starting from the day-1 to day-19 post-mating and were sacrificed on day-19 afternoon. All uterus lobes of each pregnant rat were taken and histologically processed by HE staining. Five histological slides were randomly taken as samples representing each pregnant rat and were examined for ten visual fields per slide for the measurements of diameter and wall thickness of spiral arteries. NK cells were observed immunobiological. Data analyses used Kruskal–Wallis. RESULTS: Result showed that there were significant differences of diameters and wall thickness of spiral arteries and uterine NK cells in all exposed groups compared to control (P < 0.05). Diameter and wall thickness of spiral arteries were thicker in coal dust exposure than normal pregnant rats. NK cell number was more in coal dust exposure than normal pregnant. CONCLUSION: Coal dust exposures caused the thickening of wall and narrowing of lumen of spiral arteries and NK cell counts that might influence pregnancy.
South Kalimantan is one of provinces in Indonesia that has a lot of coal minings. south kalimantan living environtment committee showed that there are 49 coal minings in 13 regions. the most coal minings are in Kotabaru, Tanah Laut and Balangan, each has 10 coal minings. Air pollution because of coal dust can effect endothelial function, such as hypertension in pregnant or preeclampsia. One of its mechanisms is coal dust can induce inflammation. One of inflammation’s indicator is high level of IL6. Inflammation disturb angiogenesis which is showed by low level of VEGF. High inflammation and low angiogenesis can induce endothelial dysfunction which is found in preeclampsia. This research’s goal was to analyze the effect of coal dust exposure to serum IL6 and VEGF level as preeclampsia induction in pregnant rattus novergicus. The design was experimental with post test only with control group design, consisted of 7 groups: control/K0 (group without coal dust exosure), group with coal dust exposure 6,25 mg/m3 for 1 hour/day (K1-1), group with coal dust exposure 12,5 mg/m3 for 1 hour/day (K1-2), group with coal dust exposure 25 mg/m3 for 1 hour/day (K1-3), group with coal dust exposure 6,25 mg/m3 for 2 hour/day (K2-1), group with coal dust exposure 12,5 mg/m3 for 2 hour/day (K2-2), and group with coal dust exposure 25 mg/m3 for 2 hour/day (K2-3).
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