Restoration of hormonal homeostasis and, as a consequence, the improvements in well-being, performance status and sexual function of the individuals has always been an indispensable aspect of anti-aging medicine. Albeit hormone replacement therapy (HRT) being the easiest and most preferred therapeutic method employed by majority of physicians, the undisputed risks associated with HRT dictate the necessity to search for alternative treatment solutions, capable of pledging nearly the same efficacy with considerably superior safety. In this regard, optimization of endogenous hormone synthesis and expression via the stimulation of hypothalamo-hypophyseal-adrenal axis with cell therapy beckons our attention as biological doctors. The current paper offers description of treatment protocols and analysis of the outcomes of biohormonal rejuvenation and revitalization by the means of cell therapy.
Chronic kidney disease (CKD) is characterized by a gradual loss of kidney function that happens over time and from the point of view of modern conventional medicine is considered to be an incurable and irreversible disease. The main risk factors attributing to CKR are diabetes mellitus, hypertension, glomerulonephritis, renal artery stenosis and family history of kidney disease. Affecting approximately 1 in 10 people of a Global population CKD imposes a significant threat to individuals’ lives and carries a major financial burden to patients and healthcare systems. CKD is the cause of at least 1 million deaths per year globally and consume nearly 6% of all medical expenses. In this article we discuss possibilities of disease control and reversal from the perspective of Biological Regenerative Medicine.
The structural composition of the skin is dynamic, exhibiting various signs of aging such as the decrease in collagen and elastin content leading to increase in tactile and visual roughness, dryness, wrinkles, fine lines and stiffness as age advances. This study was done to elicit the efficacy and potency of mesotherapy using a cocktail of triple strength nano-sized peptides from the skin, placenta, mesenchyme fortified with collagen and hyaluronic acid (HA) in the revitalisation of the skin of the dorsum of the hand. Ten male subjects suffering from mild signs of aging of the skin were treated with the formulation of MF+ SPMC + HA over the dorsum of both hands. The treatment course spanned over eight weeks with once a week application. Baseline assessment was done before the treatment and at the end of the first and second month and 90 days post-therapy, respectively, using photography, ultrasound comparison and biophysical parameters of the skin. The results proved the application of SPMC + HA rendered long-term hydration and improved the viscoelasticity of the treated area. The study concluded that mesotherapy application of MF+ SPMC extracts/peptides in combination with hyaluronic acid could be considered as a safe and effective method for rejuvenation of the skin of the dorsum of hands.
Therapeutic applications of xenogeneic remedies and various forms of cell therapy can be traced back in history for many centuries. However its clinical application in conventional medicine started in the beginning of 20th century from Switzerland and Germany. Current paper highlights the milestones of development of live cell therapy as a paradigm of regenerative medicine, discusses mechanisms of its biological function, safety of cell therapy and offers a series of case reports.
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