Restoration of hormonal homeostasis and, as a consequence, the improvements in well-being, performance status and sexual function of the individuals has always been an indispensable aspect of anti-aging medicine. Albeit hormone replacement therapy (HRT) being the easiest and most preferred therapeutic method employed by majority of physicians, the undisputed risks associated with HRT dictate the necessity to search for alternative treatment solutions, capable of pledging nearly the same efficacy with considerably superior safety. In this regard, optimization of endogenous hormone synthesis and expression via the stimulation of hypothalamo-hypophyseal-adrenal axis with cell therapy beckons our attention as biological doctors. The current paper offers description of treatment protocols and analysis of the outcomes of biohormonal rejuvenation and revitalization by the means of cell therapy.
Chronic kidney disease (CKD) is characterized by a gradual loss of kidney function that happens over time and from the point of view of modern conventional medicine is considered to be an incurable and irreversible disease. The main risk factors attributing to CKR are diabetes mellitus, hypertension, glomerulonephritis, renal artery stenosis and family history of kidney disease. Affecting approximately 1 in 10 people of a Global population CKD imposes a significant threat to individuals’ lives and carries a major financial burden to patients and healthcare systems. CKD is the cause of at least 1 million deaths per year globally and consume nearly 6% of all medical expenses. In this article we discuss possibilities of disease control and reversal from the perspective of Biological Regenerative Medicine.
Genome of eukaryotic cells contains up to 69% of the transposable elements and repetitive sequences. To a large extent it is a result of billions of years of evolution through which eukaryotes were encountering gazillions of viruses and storing the footprints of those encounters in its genome. This time Mankind deals with a novel virus belonging to the coronavirus family, which albeit being widely spread in the wildlife is new to humans. Once infected, 80% of humans experience a flu-like symptoms and eventually recover. However the real menace is posed to those whose vulnerability is determined by old age and underlying medical conditions. Akin to the scenario of alien invasion, this pandemic will leave a notable imprint on social, economic and biological aspects of human existence. How did it happen, or rather, why did we allow this to happen? Let’s ponder over the biological, medical and philosophical domains of COVID19 pandemic.
Background: Periorbital wrinkle formation is a relatively early sign of skin aging. The public interest in the reversal of aging has increased significantly among demanding patients and aesthetic practitioners within the past decades. However, many aesthetic patients, whether young or old, prefer to avoid invasive procedures wherever possible, seeking natural-looking results.Therefore, physicians have had to respond to their patient's expectations. Objectives: This study aimed to evaluate whether the synergistic anti-aging activity of MF3 Placenta 3R serum product has an influence towards the treating of wrinkles as well as skin hydration, and skin elasticity in the periorbital area. Methods: 23 healthy adult female volunteers were instructed to apply MF3 Placenta 3R serum containing a mixture of low molecular weight hyaluronic acid (LMWHA), placental peptides and extract of Malus domestica around the eye area twice daily during the study period of eight weeks. The skin measurements were performed in the periorbital area by investigating the skin elasticity (Cutometer) and skin hydration (Corneometer). Patients questionnaires were answered at 59 days. Results: The findings of the study proved a moisturizing impact of MF3 Placenta 3R serum throughout the trial that transformed into significant improvements in periocular skin hydration and elasticity. Conclusion: The tested formulation of MF3 Placenta 3R serum appears to be effective and may stimulate the periorbital skin rejuvenation in a women 44 – 52 years, resulting in the clinical appearance of smoother skin with less visible wrinkling. Further randomized, controlled studies have to be done to confirm these results.
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