Saliva as a diagnostic biofluid offers a number of advantages over blood-based testing. The role of IL-8 in oral cancer if validated further by future research can provide an easy diagnostic test as well as a prognostic indicator for patients undergoing treatment. Therefore, if it's role in tumourigenesis can be sufficiently assessed, it could open up new avenues to find out novel treatment modalities for oral cancer.
Aims
This study was designed to assess the oral alterations and oral health related quality of life (OHRQoL) in patients undergoing chemotherapy for malignancies other than oral cancer.
Methods and results
Oral alterations were studied by careful clinical examination prior to and at the end of three cycles of chemotherapy in 100 patients. OHRQoL was assessed by oral health impact profile (OHIP)‐14 questionnaire. Fifty‐four patients developed oral complications among which oral mucositis and pigmentation were the most commonly observed. OHRQoL was hampered in all patients as indicated by higher postchemotherapy scores as compared to prechemotherapy scores (P < .0001). Postchemotherapy scores were higher for patients who developed visible oral changes as compared to those who did not (P = .001). There was a weak positive correlation between the number of oral alterations and postchemotherapy scores for OHRQoL.
Conclusions
Our study emphasizes the role of oral physicians in the healthcare team delivering chemotherapeutic treatment as regular oral examination, and timely symptomatic treatment is important for the overall well‐being of the patient.
Trigeminal neuralgia (TN) is one of the most excruciating pain syndromes afflicting the orofacial region. Trigeminal neuralgia may be primary i.e. idiopathic or secondary, resulting from trauma or a CNS lesion. Considering the agonizing nature of the disease and TN being the commonest of the neural maladies affecting the orofacial region it is important for the oral physician to be aware of all available treatment options. This article makes an attempt to present a brief insight into the current treatment modalities that are on hand to treat this condition. From the perspective of the oral physician the pharmacotherapy constitutes the cornerstone in the management of TN. At the same time, it is also important to be aware and updated of the role of the oral surgeon and radiologist in the application of the array of interventional procedures available for treating TN.
SummaryA young male of Asian-Indian ethnicity reported with a complaint of a painless, slow growing swelling over the left side of lower jaw. A thorough clinical history was taken and detailed radiological exam performed. The conventional radiographic examination revealed a mixed radiolucent-radiopaque lesion with unique appearances on different radiographs. Additional computed tomographic examination discovered the involvement of several bones in the skull base. Subsequent to histopathological confirmation a final diagnosis of craniofacial fibrous dysplasia was made. This case is particularly unique and of didactic importance as well because the various textbook descriptions for radiological appearances of fibrous dysplasia were found in the same case.
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