Trigeminal neuralgia: An insight into the current treatment modalities

Punyani, Silky R.; Jasuja, Vishal Ramesh

doi:10.1016/j.jobcr.2012.10.002

Cited by 15 publications

(8 citation statements)

References 26 publications

(19 reference statements)

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“…It is characterized by severe intermittent facial pain, which usually involves one side of the face. The pain is typical of a throbbing nature [3]. It is also called tic douloureux (painful tic) because patients often distort the face because of severe pain.…”

Section: Discussionmentioning

confidence: 99%

Trigeminal Neuralgia Induced Headache: A Case Report and Literature Review

Kataria¹,

Ahmed²,

Ali³

et al. 2020

Cureus

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A 51-year-old woman with a past medical history of migraine presented with severe headache for the last three weeks. The pain was intermittent and throbbing in nature. She has not experienced any headaches in the past several years. She took her migraine pills and over-thecounter analgesics, but the pain did not resolve. Initial evaluation including physical exam and neurological exam was normal. Her serum chemistry was unremarkable and CT scan of the brain was nonsignificant. The patient was diagnosed with possible trigeminal neuralgia and the pain resolved after being started on tegral (carbamazepine). Unilateral headache is a typical presentation of atypical trigeminal neuralgia and is rarely reported in literature.

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Section: Discussionmentioning

confidence: 99%

Trigeminal Neuralgia Induced Headache: A Case Report and Literature Review

Kataria¹,

Ahmed²,

Ali³

et al. 2020

Cureus

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“…Trigeminal neuralgia (TN) is a disease characterized by frequent unilateral, sudden and paroxysmal pain attacks affecting the orofacial region, often described as "the worst pain in the world" by patients [1]. TN affects one or more branches of the trigeminal nerve, often the second or third branches [2].…”

Section: Introductionmentioning

confidence: 99%

Prevalence of trigeminal neuralgia patients in the community: A retrospective study

Kucuk¹

2019

Ann Clin Anal Med

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Aim: The aim of this study is to evaluate the prevalence of trigeminal neuralgia (TN) in Adıyaman and its surrounding populations. Material and Method: The study population consisted of 154.969 patients admitted to the Adıyaman University, Department of Oral and Maxillofacial Surgery between 2015 and 2018. Clinical records of 41 patients diagnosed with TN were retrospectively reviewed. Demographic data and clinical characteristics of the patients were recorded. Localization, age and sex distribution and the prevalence of TN were determined. Results: Among the 41 cases with TN, 27 were female and 14 were male. The mean age of the patients was 58.59 ± 16.38 years. Thirty-nine patients (95.1%) had unilateral and 2 patients (4.9%) had bilateral TN. While the mandibular branch (V3) involvement of the trigeminal nerve was observed in 16 patients, 5 patients showed maxillary branch (V2) involvement, and 3 patients exhibited ophthalmic branch (V1) involvement. In addition, V1+V2 involvement was observed in 1 patient, V2+V3 involvement was observed in 5 patients and V1+V2+V3 involvement was described in 11 patients. Overall, the prevalence of TN was found to be approximately 0.03% (26/100.000). Discussion: TN is a rare disease, estimation of its prevalence is difficult, hence, the literature on the prevalence and of TN is limited. The prevalence rate is about 4.5-29.5 per 100.000 individuals in other studies. The present study revealed that the prevalence of TN in Adıyaman and its surroundings was 26/100.000. This study may be the first one in Turkey to investigate the prevalence of TN.

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“…12,13,[25][26][27][28][29] Local anesthetics provide nonselective blockade of the "open" state of the voltagegated sodium channel affecting both sensory and motor neurons. 30 That said, the primary mechanism of action of the anticonvulsant carbamazepine, used in the treatment of trigeminal neuralgia, 31,32 prolongs the "inactivated" state of select voltage-gated sodium channels. In the peripheral nervous system, these targeted sodium channels are predominantly expressed on sensory neurons and result in limited firing rates of those neurons.…”

Section: Introductionmentioning

confidence: 99%