Abstract:Water resources are important and irreplaceable natural and economic resources. Achieving a balance between economic prosperity and protection of water resource environments is a major issue in China. This article develops a data envelopment analysis (DEA) approach with undesirable outputs by using Seiford's linear converting method to estimate water use efficiencies for 30 provinces in China, from 2008-2016,and then analyzes the influencing factors while using a DEA-Tobit model. The findings show that the overall water use efficiency of the measured Chinese provinces, when considering sewage emissions as the undesirable output, is 0.582. Thus, most regions still need improvement. Provinces with the highest water efficiency are located in economically developed Eastern China. The spatial pattern of water use efficiency in China is consistent with the general pattern of regional economic development. This study implies that factors like export dependence, technical progress, and educational value have a positive influence on water use efficiency. Further, while industrial structure has had a negative impact, government intervention has had little impact on water use efficiency. These research results will provide a scientific basis for the government to make plans for water resource development, and it may be helpful in improving regional sustainable development.

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The aim of this study is to investigate the long-term immunogenicity of inactivated split-virion 2009 pandemic influenza A H1N1 vaccine after a single immunization. We recruited 480 adults, aged 18-60 years, for a placebo-controlled, observer-masked, single-center clinical study. We randomly assigned subjects into four groups: 15 μg, 30 μg and 45 μg of hemagglutinin (HA) dosage groups, and a placebo control group. Finally, 259 subjects completed the entire study. The rates of seroconversion and seroprotection and the geometric mean increase (GMI) fulfilled the criteria of the European Medicines Agency (EMEA) for influenza vaccine for 180 days after vaccination in all three dosage groups. However, the seroprotection rates of all dosage groups were below 70% at day 360 post vaccination, while the seroconversion rates and the GMI continued to meet the licensure criteria at this time point. In conclusion, a single dose of 15 μg HA vaccine could induce a protective immune response persisting for at least six months in adults. This study could be beneficial for the future development of influenza vaccines conferring long-term immunity.

Multi-linear M-tensor equation is a complex system of linear equations, whose coefficient is a higher-order tensor. Recurrent neural network (RNN) has great advantages in the processing of sequence data, especially in the processing of nonlinear systems, showing a very potent ability. In this paper, solving the multi-linear M-tensor equation is transformed into an error function from the perspective of control science. By controlling the error to zero, the real solution to the error function is approached to the theoretical solution. The model is discretized for the convenience of implementation in computers. Moreover, the relevant theoretical analyses are provided, and the effectiveness and advantages of the proposed method are proved by comparing it with the Newton iteration (NI) neural algorithm.

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The mitochondrial genome (mitogenome) is recognized as an effective molecular marker for studying molecular evolution and phylogeny. The family Mysmenidae is a group of widely distributed and covert-living spiders, of which the mitogenomic information is largely unclear. In this study, we obtained the first four complete mitogenomes of mysmenid spiders (one aboveground species: Trogloneta yuensis, and three cave-dwelling species: T. yunnanense, Yamaneta kehen and Y. paquini). Comparative analyses revealed that their lengths ranged from 13,771 bp (T. yuensis) to 14,223 bp (Y. kehen), containing a standard set of 37 genes and an A + T-rich region with the same gene orientation as other spider species. The mitogenomic size of T. yunnanense was more similar to that of Yamaneta mitogenomes than that of T. yuensis, which might indicate the convergent evolution of cave spiders. High variability was detected between the genera Trogloneta and Yamaneta. The A + T content, the amino acid frequency of protein-coding genes (PCGs) and the secondary structures of tRNAs showed large differences. Yamaneta kehen and Y. paquini contained almost identical truncated tRNAs, and their intergenic spacers and overlaps exhibited high uniformity. The two Yamaneta species also possessed a higher similarity of start/stop codons for PCGs than the two Trogloneta species. In selective pressure analysis, compared to Yamaneta, Trogloneta had much higher Ka/Ks values, which implies that selection pressure may be affected by habitat changes. In our study, the phylogenetic analysis based on the combination of 13 PCGs and two rRNAs showed that Mysmenidae is a sister clade to the family Tetragnathidae. Our data and findings will contribute to the better understanding of the origin and evolution of mysmenid spiders.