Background: In Benin, men who have sex with men (MSM) do not always use condoms during anal sex. Preexposure prophylaxis (PrEP) using Truvada® (tenofovir disoproxil fumarate / emtricitabine) may be a complementary HIV prevention measure for MSM. This study aimed at identifying the potential facilitators and barriers to the use of PrEP. Methods: This was a cross-sectional study conducted in 2018 among male-born MSM aged 18 years or older who reported being HIV-negative or unaware of their HIV status. The participants were recruited by the RDS technique (respondent driven sampling) in six cities of Benin. Logistic regression analyses, adapted to RDS statistical requirements, were performed to identify the factors associated with PrEP acceptability. Results: Mean age of the 400 MSM recruited was 26.2 ± 5.0 years. PrEP was known by 50.7% of respondents. The intention to use PrEP was expressed by 90% of MSM. If PrEP effectiveness were 90% or more, 87.8% of the respondents thought they would decrease condom use. In multivariate analysis, the facilitators associated with PrEP acceptability were: not having to pay for PrEP (odds ratio (OR) = 2.39, 95% CI: 1.50-4.46) and its accessibility within MSM networks (OR = 9.82, 95% CI: 3.50-27.52). Only one barrier was significant: the concern that taking PrEP be perceived as marker of adopting HIV risky behaviors (OR = 0.11, 95% CI: 0.04-0.30). Conclusion: In Benin, not all MSM know about PrEP. But once well informed, the majority seems willing to use it if made available. The free availability of the drug and its accessibility in the MSM networks are important facilitators. The possibility of decrease in condom use should not be a barrier to the prescription of PrEP if made available.

Cases of HIV are common in Benin, with infection rates varying according to socioeconomic and cultural factors, and by region. Certain segments of the population, such as prison inmates, sex worker clients and truck drivers are at high risk for HIV/AIDS. The aim of this study is to identify which behavioral and serological indicators contribute to the spread of HIV among prisoners. A total of 496 inmates from prisons located in all major cities in Benin were surveyed. Data was collected through interview sessions carried out using a questionnaire and through blood samples. The results show that most inmates are Beninese (83.5%), and the average age is 33 years (range: 14-80 years). No prisoner reported using a condom the last time they engaged in sexual intercourse. Blood exposure was found in 14.6% of inmates and HIV was detected in 1.4% of cases. Our analysis indicates that the length of detention and gender are factors that influence HIV status. However, age, education, nationality and HIV awareness had no significant effect on HIV prevalence among inmates. The results highlight the need to raise awareness in prisons about HIV. This can be achieved by strengthening communication strategies and by organizing HIV and sexually transmitted diseases information sessions for both prison officers and inmates.

Men who have sex with Men (MSM) are a key population in the transmission of Human Immunodeficiency Virus (HIV) infection. In Benin, there is a lack of strategic information to offer appropriate interventions for these populations who live hidden due to their stigmatization and discrimination. The objective is to identify contributing factors that affect HIV incidence in the MSM population. Study of a prospective cohort of 358 HIV-negative MSM, aged 18 years and over, reporting having had at least one oral or anal relationship with another man during the last 12 months, prior to recruitment. The monitoring lasted 30 months with a follow-up visit every six months. Univariate analyses and a Cox proportional hazards multivariate regression were used to examine the association between bio-behavioral, socio-demographic and knowledge-related characteristics with HIV incidence. The retention rate for the follow-up of the 358 participants was 94.5%. On the 813.5 personyears of follow-up, 48 seroconversions with an HIV incidence of 5.91 per 100 person-years were observed (95% CI: 4.46-7.85). Factors associated with the high risk of HIV were age (HR = 0.4; 95% CI: 0.2-0.8), living in couple (HR = 0.5 95% CI: 0.2-0.96) and the lack of condom systematic use with a male partner during high-risk sex (HR = 3.9; 95% CI: 1.4-11.1). HIV incidence is high within MSM population and particularly among young people. Targeted, suitable and cost-effective interventions for the delivery of the combination prevention package in an environment free of stigma and discrimination are necessary and vital for reaching the 90x90x90 target.

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RESUMEObjectif : L'usage de Ocimum gratissimum Lamiaceae (Basilic tropical) est très répandu au Bénin. Cette utilisation repose sur les connaissances empiriques des populations. Il est légitime de se demander si les vertus attribuées à cette plante reposent sur des bases scientifiques et sa consommation sans conséquences néfastes pour la santé humaine. Méthodologie et résultats : Une étude ethnobotanique a ciblé les vendeurs de légumes feuilles des trois principaux marchés (Dantokpa ; Saint Michel ; Vêdoko), quelques phytothérapeutes, des agents de santé et des consommateurs de Cotonou la capitale de la République du Bénin. Elle a été complétée par une étude phytochimique basée sur des réactions de précipitations différentielles, complétée par le dosage des métaux lourds (Plomb ; Cadmium), de quelques éléments nutritifs et oligo-éléments par spectrophotométrie d'absorption moléculaire. Il ressort des investigations plusieurs usages de Ocimum gratissimum Linn (médicinal ; alimentaire ; rituel ; chimique ; ornemental). Cette plante renferme plusieurs groupes phytochimique (phénoliques ; azotés ; stéroïdes ; terpènes ; mucilages ; dérivés cyanogéniques), des éléments nutritifs (Protéines ; Azote ; Fer ; Zinc ; Cuivre). Par ailleurs, nos résultats montrent la présence de métaux lourds (Plomb ; Cadmium) dans des concentrations supérieures aux normes OMS. Conclusion et application des résultats : Les résultats des analyses phytochimiques et nutritionnelles confirment les usages empiriques identifiés lors de l'étude ethnobotanique. Cette plante est un remède dans la prévention et le traitement de certaines maladies, un complément alimentaire, une solution alternative dans la lutte chimique. Toutefois, la présence des Éléments Traces Métalliques avec des concentrations supérieures aux normes OMS traduit un risque potentiel pour la santé humaine. Il urge pour l'état central, les partenaires ABSTRACT Objective: The use of Ocimum gratissimum Lamiaceae (African Basil) is widespread in Benin. This study evaluated whether the virtues attributed to this plant are focused on rational basis and that its consumption is without adverse consequences for human health. Methodology and Results : An ethnobotanical study targeting leaves from vegetable vendors in the three major markets (Dantokpa ; Saint Michel ; Vêdoko), some herbalists, health workers and consumers was conducted in Cotonou the capital city of Benin. A phytochemical study based on differential precipitation reactions was carried out, supplemented by the determination of heavy metals (lead, cadmium) and some nutrients by molecular absorption spectrophotometry. The investigations revealed several uses of Ocimum gratissimum Linn (Lamiaceae) i.e medicinal, food, ritual, chemical and ornamental. It contains phytochemicals compound such as phenolic; nitrogen; steroids; terpenes; mucilage; derived cyanogenic and several nutrients (protein; Nitrogen; Iron; Zinc; Copper). The results also reveal the presence of heavy metals (lead, cadmium) in concentrations above the WHO standa...

État des lieux des infections associées aux soins dans deux hôpitaux publics du sud Benin: Centre Hospitalier Universitaire de Zone d'

Transgender individuals are recognized globally as a key population that is at heightened risk than the general population for transmitting and contracting sexually transmitted infections (STIs) and human immunodeficiency virus (HIV). One of the social outcomes of the gender transition process is the adoption of risky behaviours as coping strategies. Examining the unique health-related needs of transgender individuals in Benin, this study describes the experience of being transgender, along with the social and community ramifications associated with this identity. The research team conducted a cross-sectional study in 2017. Study participants were recruited via respondent-driven sampling among networks across Benin. Inclusion criteria included self-identifying as transgender and being over 15 years of age. Data were collected via questionnaires regarding individuals' management of the gender transition, reactions within their community and social spheres, and engagement in risky behaviours. A total of 326 transgender individuals were identified with a majority of participants being born biologically male (89.57%). The average age was 24.13±4.88, with a strong representation of students (36.50%). In 64.72% of cases, participants' families were informed of their transgender identity. The overall attitude of families was of acceptance/support in 7 cases out of 10. Stigmatization and discrimination were reported by 50% of the subjects and 59.02% were subjected to at least one assault. Among these, half were unable to pursue legal action in response, with the main reason being a lack of knowledge of their options for legal recourse. Having multiple sexual partners was the most common risky behaviour among participants, occurring in 81.54% of the cases. Transgender individuals constitute a population with specific needs in Benin. The services and interventions dedicated to this population must integrate the prevention of STIs and HIV, along with providing legal, social and psychological support.

Introduction The issue of sexually transmitted infections (STIs) and Human Immunodeficiency Virus (HIV)/Acquired Immune Deficiency Syndrome (AIDS) cannot be solved without considering the transgender population. This research aims to describe the knowledge, attitudes and sexual behaviors of transgender individuals faced with the risk of STIs and HIV/AIDS in Benin. Methods Transgender individuals were selected by respondent-driven sampling throughout the country in 2017. Included in this analysis were individuals who identified as transgender and adopted its mode of expression, aged 15 years and greater, and who gave their consent to participate. Results A total of 308 transgender individuals were surveyed, of which 89.6% were of male gender at birth. The participants had a good level of knowledge in the matter of STI and HIV/AIDS. In fact, 99.9% among them cited at least one symptom of STIs; 95.1% cited the three main methods of transmission of HIV and 54% are aware the risk of sexual transmission of HIV is higher between men. Participants were more than 90% likely to declare a positive attitude to care for persons living with HIV (PLWHIV) or to share the same room with them (93.2%). Concerning sexual behaviors, the average age at the first sexual encounter as a transgender individual was 14 years old. During the last three months, transgender individuals declared three regular male partners on average. The usage of condoms during the last sexual intercourse was reported in 86.6% of cases. Knowledge of the serological status of the sexual partner (31.7%) and the loss of sensation induced by the condom (26.8%) constituted the main reasons of non-usage of condoms. Conclusions Although adopting some risky sexual behavior, transgender individuals are a population that is relatively well informed and with favorable attitudes regarding STIs and HIV/AIDS. These factors are significant assets to be considered in the development of programs for STIs and HIV/AIDS control. Key messages Transgender individuals good level of knowledge is an asset for STIs/HIV control. Sexual multi-partnership seems to be common despite a good level of knowledge.