Objectives:To determine whether the mean platelet volume (MPV) and MPV/platelet (PLT) values can be used in the study of sepsis and systemic inflammatory response syndrome (SIRS).Methods:In this retrospective case-controlled study, 69 sepsis, 69 SIRS patients, and 72 control group who were treated in the years 2012-2013 were reviewed, and both the MPV and MPV/PLT rates were evaluated in all groups at Kahramanmaras Sutcu Imam University Intensive Care Unit, Kahramanmaras, Turkey.Results:Statistically significant difference was found between sepsis, SIRS, and control groups when comparing the MPV and MPV/PLT ratio (p<0.05), and no significant difference was found between sepsis and SIRS groups in terms of MPV and MPV/PLT ratio (p>0.05). Mean platelet volume values for sepsis and control groups was 10.07/8.731 femtoliter (fL) (p=0.000), and 9.45/8.731 fL (p=0.000) for SIRS and control groups. In the group of sepsis patients, the MPV was found to be at cut-off 8.915, sensitivity 71%, and specificity 63.9%. In the group of patients with SIRS, MPV was found to be at cut-off 8.85, sensitivity 69.6%, and specificity 62.5%. For the MPV/PLT values, the specificity and sensitivity were found to be insignificant.Conclusion:This study shows that although there was no significant reduction in the PLT values between the sepsis and SIRS patients, the MPV and MPV/PLT ratio values were found to have significant differences. However, the specificity and sensitivity of the values were not reliable standard to be used as a test.

Bir üniversite hastanesi noroloji yoğun bakım ünitesinde gelişen enfeksiyonların değerlendirilmesi Evaluation of nosocomial infections in a neurological intensive care unit of a university hospital Amaç: Hastane enfeksiyonları (HE) sıklığı, uzamış yaşam, gelişen teknoloji, artmış invaziv girişimler ve uzamış yatış nedeniyle giderek artmaktadır. Yoğun bakım üniteleri (YBÜ) HE'nin en sık görüldüğü hastane birimleridir. Nöroloji YBÜ (NYBÜ)'de gelişen HE'ler altta yatan primer hastalıklar, genel durum bozukluğu, artmış invaziv işlemler sebebi ile artmış mortaliteye yol açar. Bu çalışmada NYBÜ'de bir yıl içinde invaziv alet kullanımı gelişen enfeksiyonları, izolatlarını değerlendirmeyi planladık. Gereç ve Yöntem: Çalışmaya 2017 yılı içerisinde takip edilen 232 hasta alınmış, enfeksiyon kontrol komitesi (EKK) hemşireleri ve Enfeksiyon Hastalıkları Anabilim Dalı'nca NYBÜ'ne gerçekleştirilen vizitlerde HE tanısı almış hastalar, izolatlar, direnç profilleri, tutulum tanımları incelenmiştir. Bulgular: Çalışmamızda NYBÜ'de yatan hastalarda mortalite %27,15, HE gelişen grupta ise mortalite %56,66 olarak bulunmuştur. En sık görülen enfeksiyon %43,3 ile ventilatör ilişkili pnömoni (VIP) en sık etken ise %28,9 ile Acinetobacter baumannii saptanmıştır. Sonuç: NYBÜ'de EKK'nın sık rastlanan nozokomiyal patojenlerin yayılma ve bulaşmasına karşılık alacağı tedbirlere uyum sağlamak, standart önlemlere ve el hijyenine riayet etmek ve gereksiz invaziv alet kullanımından kaçınmak gerekmektedir. Enfeksiyon oran ve hızları değerlendirilmeli, ulusal sürveyans verileri ile karşılaştırılmalıdır. Sık karşılaşılan patojenler ve antibiyotik direnç özelliklerinin iyi tanımlanması ampirik tedavinin uygun ve vaktinde başlanmasında, morbidite ve mortalite azalmasında önemlidir. Anahtar Sözcükler: Enfeksiyon; enfeksiyon Kontrol; yoğun bakım ünitesi. Introduction: The frequency of nosocomial infections (NI) are gradually increasing because of prolonged life, advancing technology, increasing invasive procedures. NI are mostly seen in intensive care units. NI, developed in neurology intensive care unit (NICU), lead to increased mortality because of underlying primer diseases, general medical condition disorder, and increased invasive operations. In this study, we aimed to evaluate the use of invasive instrument,developing infections,and isolations in a year. Methods: 232 patients (followed in 2017) are included in this study. Patients diagnosed with NI, isolates, resistance profiles, and involvement are examined in the visits to NICU by the nurses of infection control committee(ICC) and the Department of Infectious Diseases. Results: In our study, the mortality in NICU patients is %27,15 and in NI group the mortality is %56,66. The most common infection is ventilator-associated pneumonia with %43,3 (VAP) and the most common factor is Acinetobacter baumannii with %28,9. Discussion and Conclusion: It is necessary to coordinate with precautions (taken by ICC) against to extension and contagion of common nosocomial pathogens, to consider standart precautio...

Background: Gemella is a Gram-positive, catalasenegative, facultatively anaerobic coccus bacterium. It is a member of the normal flora and rarely causes infection. This study aims at evaluating, accompanied by the literature, Gemella-associated infections that are also present in the normal flora.

Introduction:The human population is aging at an astonishing rate. The aim of this study is to capture a situation snapshot revealing the proportion of individuals aged 65 years and over among inpatients in healthcare institutions in Turkey and the prevalence and type of infections in this patient group in order to draw a road map. Materials and Methods: Hospitalized patients over 65 years at any of the 62 hospitals in 29 cities across Turkey on February 9, 2017 were included in the study. Web-based SurveyMonkey was used for data recording and evaluation system. Results: Of 17,351 patients 5871 (33.8%) were !65 years old. The mean age was 75.1 AE7.2 years; 3075 (52.4%) patients were male. Infection was reason for admission for 1556 (26.5%) patients. Pneumonia was the most common infection. The median length of hospital stay was 5 days (IQR: 2-11 days). The Antibiotic therapy was initiated for 2917 (49.7%) patients at the time of admission, and 23% of the antibiotics prescribed were inappropriate. Healthcare-associated infections developed in 1059 (18%) patients. Urinary catheters were placed in 2388 (40.7%) patients with 7.5% invalid indication. Conclusion:This study used real data to reveal the proportion of elderly patients in hospital admissions. The interventions done, infections developed during hospitalization, length of hospital stay, and excessive drug load emphasize the significant impact on health costs and illustrate the importance of preventive medicine in this group of patients.

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