HighlightsCondom catheter is frequently used to manage male urinary incontinence but should not be used carelessly or overlooked.Even if they are rare, penile strangulation and gangrene may occur and are severe complications.Treatment is based on debridement, broad-spectrum antibiotics and skin grafting. It may result in partial or total penectomy.Proper care and routine maintenance of condom catheters are mandatory in order to prevent devastating complications.Appropriate care is necessary, especially in debilitated and psychiatric populations.
Highlights
Solitary fibrous tumor is a rare entity, representing 2% of all soft tissue tumors.
The disease is usually described in the thoracic cavity, only 105 cases of renal solitary fibrous tumor have been reported.
Solitary fibrous tumors are usually asymptomatic thus they are diagnosed as renal cell carcinoma and treated as such.
Typical immunohistochemical characteristic is a high positivity for CD34.
As solitary fibrous tumor has a malignant potential, careful follow-up is mandatory.
Background
Angiotensin‐converting enzyme (ACE) plays a pivotal role in several pathologies including cancers. The association of insertion/deletion (I/D) polymorphism of the ACE gene with prostate cancer (PC) risk remains controversial. We aimed to investigate for the first time, to our Knowledge, in North Africa the potential relationship between ACE I/D polymorphism with PC susceptibility and clinical outcomes of PC patients.
Methods
This case‐control study included 143 healthy individuals and 124 patients diagnosed with PC. Using genomic DNA, the samples were genotyped for ACE I/D polymorphism by polymerase chain reaction (PCR).
Results
We found that The D allele is significantly associated with an increased risk of PC and D/D + D/I genotypes were at 3 times increased risk of PC ([p = 0.005], OR = 2.95, IC 95% = 1.26–7.09) compared with I/I genotype (p = 0.003, OR = 0.3, IC 95% = 0.12–0.74). We observed an association between D/D and D/I genotypes with advanced age (≥70 years) (p = 0.014; r2 = 0.22). Furthermore, there is a significant prediction of advanced Gleason score ≥8 based on epidemiological parameters and ACE genotype (p = 0.000; R2 = 0.349), although no significant association was observed with stage and metastasis.
Conclusion
The ACE I/D polymorphism is likely to predispose to PC and could play a role in PC progression and aggressiveness.
The urachus is an embryologic remnant which degenerates after the birth. An infected urachal cyst is one of a spectrum of presentations of urachal pathology, all of which are rare in adulthood. Infected urachal cyst is a rare pathology in adult women and it should be considered in the differential diagnosis of acute abdomen. We report here a case of a 50-year-old women with an infected urachal cyst reveled by an acute abdomen.
HighlightsSkin metastases of urothelial bladder carcinoma are rare.The inflammatory presentation, as seen in our case, is exceptional.Diagnosis requires immunohistochemical study of a skin biopsy.The prognosis after the appearance of cutaneous metastasis is poor.
Urethral foreign bodies are rare in daily practice, especially in adolescents with no evident history of mental illness. The presentation is usually delayed and a wide variety of objects may be implicated. Treatment by minimally invasive procedures (endoscopy), if possible, is preferred to minimize bladder and urethral injuries and psychiatric evaluation is mandatory to detect an underlying mental disorder. Despite the available literature on self-inserted urethral foreign bodies; the case we report here of urethral self-insertion of a sewing needle in a 14 year-old boy for autoerotic stimulation is very rare.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.