The purpose of this research was to investigate the prophylactic effects of glutamine on muscle protein synthesis and degradation in rats with ethanol-induced liver injury. For the first 2 weeks, Wistar rats were divided into two groups and fed a control (n = 16) or glutamine-containing diet (n = 24). For the following 6 weeks, rats fed the control diet were further divided into two groups (n = 8 per group) according to whether their diet contained no ethanol (CC) or did contain ethanol (CE). Rats fed the glutamine-containing diet were also further divided into three groups (n = 8 per group), including a GG group (glutamine-containing diet without ethanol), GE group (control diet with ethanol), and GEG group (glutamine-containing diet with ethanol). After 6 weeks, results showed that hepatic fatty change, inflammation, altered liver function, and hyperammonemia had occurred in the CE group, but these were attenuated in the GE and GEG groups. Elevated intestinal permeability and a higher plasma endotoxin level were observed in the CE group, but both were lower in the GE and GEG groups. The level of a protein synthesis marker (p70S6K) was reduced in the CE group but was higher in both the GE and GEG groups. In conclusion, glutamine supplementation might elevate muscle protein synthesis by improving intestinal health and ameliorating liver damage in rats with chronic ethanol intake.
BACKGROUND Poor sleep duration and quality were previously reported to increase the risk of obesity. This study was aimed to evaluate the impact of sleep quality and duration on leptin, appetite, and adiposity in Indonesian adults. METHODS This cross-sectional study recruited adults in Yogyakarta, Indonesia, in 2016. Sleep quality was assessed using the Pittsburgh sleep quality index, appetite was evaluated using the community nutrition appetite questionnaire, and dietary intake was assessed by interviews using the semi-quantitative food frequency questionnaire. Sleep duration was also asked. Obesity indices were measured using the body mass index (BMI), waist-hip circumference, and percentage of body fat. Leptin was analyzed using the enzyme-linked immunosorbent assay. A Spearman analysis was done to evaluate the correlation between sleep quality, sleep duration, anthropometric measures, dietary intake, appetite, and leptin. RESULTS 244 adults participated in this study. This study showed that lower sleep quality and duration was significantly correlated with higher body weight (r = 0.129, p = 0.043 and r = −0.228, p<0.001), BMI (r = 0.176, p = 0.006 and r = −0.202, p = 0.001), and waist circumference (r = 0.179, p = 0.005 and r = −0.254, p<0.001). There was a correlation between poor sleep quality and higher leptin concentration (r = 0.186, p = 0.004). Sleep quality and duration were not associated with appetite (r = 0.109, p = 0.109 and r = −0.043, p = 0.500). CONCLUSIONS This study found that lower sleep quality was correlated with higher BMI, higher leptin concentration, but not appetite.
Stunting merupakan salah satu masalah pembangunan kesehatan di Indonesia. Survei Status Gizi Indonesia (2021) mencatat, prevalensi stunting di Kabupaten Nganjuk mencapai 25,3%. Penanganan stunting harus melibatkan komitmen bersama dan peran lintas sektor. Penelitian ini bertujuan mendeskripsikan peran sosial lintas sektoral dalam percepatan penurunan stunting di Kabupaten Nganjuk. Penelitian ini menggunakan konsep collaborative governance Ansell & Gash sebagai pisau bedah analisis. Penelitian ini menggunakan pendekatan kualitatif dengan pengumpulan data melalui teknik wawancara model focus group discussion kepada aparat desa, bidan dan penyuluh KB. Penelitian ini mengungkapkan bahwa peran sosial antar aktor dalam konteks tata kelola kolaboratif cukup efektif dalam mempercepat penurunan stunting di Kabupaten Nganjuk. Pemerintah desa berperan dalam merumuskan kebijakan penganggaran melalui alokasi dana desa untuk mendukung program tersebut. Bidan dan penyuluh KB bekerja sama merumuskan program yang efektif untuk disampaikan pada musyawarah perencanaan pembangunan desa. Pendampingan terhadap keluarga stunting dan berisiko stunting terus dilakukan melalui peran serta aktif bidan dan Tim Pendamping Keluarga. Kendala yang dialami pelaku sinergi lintas sektor dalam percepatan penurunan stunting adalah konstruksi pengetahuan dan perilaku orangtua tentang pola asuh anak yang masih lemah. Oleh karena itu, dalam memperkuat implementasi tata kelola kolaboratif dalam percepatan pengurangan stunting, diperlukan persamaan persepsi dan motivasi bersama yang kuat diantara para aktor sosial yang terlibat. Selanjutnya capacity for joint action, dimana setiap aktor terlibat dalam kegiatan kerjasama untuk meningkatkan kapasitas diri dan inklusivitas peran untuk mencapai tujuan bersama.
The aim of website in university are to provide information about profiles, academic programs, facilities and facilities, activities and achievements. The website is the first media interaction and engage interaction to prospective students and public users. To find out how far the Nutrition Program website can be accepted by users, it is necessary to conduct an assessment and a way to improve the quality of service to students. The aims of this study were (1) to determine the quality of information on the nutrition study program website (2) To determine the quality of user service interaction (3) To determine the usability of the nutrition study program website. This research is a quantitative descriptive study with 100 respondents from the Unesa Nutrition Undergraduate Study Program as many as 100 people. The measurement of website service quality is taken using the Webqual instrument. Data collection was carried out in June 2022, using google form. The average score for the Website Information quality dimension of the Unesa Nutrition Undergraduate Study Program is 3.576 (respondents are very satisfied). On the service interaction quality dimension of the website, the average score was 3.349 (satisfied) and for the website usability dimension, the average score was 3.533 (very satisfied). Overall, the respondents were very satisfied with the website with an average score of 3.555. Some suggestions for improvements to the website include adding information about student achievements, scholarship information, information on internships and job vacancies, templates for correspondence/administration, history, video profiles, and curriculum information.
Student-athletes have tremendous potential to be developed into elite athletes. Special sports schools provide opportunities for student-athletes to develop their potential more optimally. The implementation of boarding schools in sports-specific schools provides adequate facilities for student-athletes to focus on careers in sports and education. The COVID-19 pandemic has raised concerns about how the physical activity and body proportions of student-athletes undergo programs in special sports schools. For this reason, the purpose of this study was to describe the condition of physical activity and body proportions of studentathletes in special sports schools. This research is included in the descriptive type. A total of 66 student-athletes (29 boys and 27 girls) were involved in the study. The research instrument uses a physical activity questionnaire that measures physical activity according to the FITT principle and reports height and weight. Body composition was determined using BMI. Data analysis used descriptive, t-test, and ANOVA. The results showed that 6.1% of student-athletes felt that their exercise frequency was insufficient, 84.8% felt it was appropriate, and 9.1% felt it was too much. As many as 50% of student-athletes feel the intensity of their exercise is moderate, and 50% feel heavy. As many as 80.3% of student-athletes felt that the duration of their training was sufficient, and 19.7% felt that it was long. As many as 84.8% of student-athletes felt that the training they got was sufficient and 15.2% found it difficult. BMI shows that as many as 24.2% of student athletes are thin, 56.1% are normal, and 19.7% are obese. Evidently, the variable frequency of exercise affects BMI (F = 5.1, p = 0.009), BMI and exercise activity correlated (r = 0.34, p = 0.005) non-linearly (F = 9.149, p = 0.004).
This study analyzed arm flexion isometric force, upper extremity movement, and ball toss position toward ball speed in tennis flat serve. Nine tennis players aged 20.78 ± 5.044 years old participated in this study and were chosen as research samples by using the purposive sampling method. The independent variables of this study were arm flexion isometric force, upper extremity movement, and ball toss position. The kinetic data were collected by Force Decks by Vald Performance, and kinematic data were analyzed by Kinovea 0.9.4 computer software. The dependent variable was ball speed which was measured after the impact with racket by using Bushnell Velocity Speed Gun type 101911. The data were analyzed by using descriptive analysis and Kolmogorov-Smirnov normality test in SPSS statistical software. Furthermore, multiple linear regression was performed to find the correlation between variables. As a result, all of the data were in the normal distribution. The kinetic data were analyzed by using the descriptive method. The mean of arm flexion isometric peak force was 131.22 ± 41.27 Newton, arm flexion isometric average force was 121.44 ± 42.08 Newton, and rate force development was 270.33 ± 112.88 milliseconds. The kinematic data were also analyzed by using the descriptive method. The mean arm flexion and ball height in ball release position were 120.39 ± 14.65 º and 165.76 ± 25.39 cm. The mean peak ball position was 337.08 ± 23.92 cm. At the ball impact position, the mean of the hip torso, arm flexion isometric, and ball height were 30. 46 ± 15.42 º, 186.93 ± 14.43 º, and 258.77 ± 26.51 cm. The mean ball speed was 80.23 ± 16.38 km/h. There was a significant correlation between ball height in peak position and impact position (R Score > .666). Furthermore, kinematic had a significant correlation with ball speed (R Score > .666).
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