A new series of benzothiazole appended triazole derivatives were synthesized.
Characterization is done by FT-IR, Mass, 1H and 13C NMR spectroscopic techniques. The
newly synthesized compounds were screened for antioxidant and anti inflammatory activities.
Experimental data hypothesized compound 7b as highly potent cytotoxicant with lengthened
activity. Structure –activity relation interrelates the biological activity and chemical moiety of
the molecule. Structurally, 7b is a benzothiazolyltriazole having a pyrrolidine group (five
membered ring) attached to two CH2 groups and methyl substituent at 7th position of the
benzothiazole ring
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Compounds containing electron donating groups show the promising antimicrobial and antioxidant activities, compounds with CH and Cl substitution show excellent anti-TB activity. Synthesized molecules may become potential candidates for the clinical trials.
Among air and soil, water pollution is considered as an important one. Deterioration of water resources by the addition of various pollutants leads to the major threat to water quality and use of water for domestic purpose which leads to unaesthetic. For the plants, animals and human beings dyes are considered as most hazardous among various water pollutants. The present paper describes the adsorption behaviour of adsorbent almond husk with respect to dyes of Crystal violet, Bromocresol green, Pararosaniline and Victoria blue was investigated. The batch method was used and parameters like pH, adsorbent dosage, contact time and initial and final concentration of dyes were studied. Adsorbent used to be effective, with total removal of all dyes of 90%, with higher percentage removal from bromocresol green 97.5%, Crystal violet 96.9%, Pararosaniline 95.6% and Victoria blue 95%. Almond husk was an effective adsorbent with maximum percentage removal of 97.5% bromocresol green. Adsorbent was analysed by the instrument of scanning electron microscopy and Fourier infrared spectroscopy. In the present study almond husk almond husk was studied as a very good adsorbent for the removal of dyes from the aqueous media. Isotherm model of Langmuir, Freundlich and Dubinin-Radushkevich were considered to be favourable.
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