A three-dimensional (3D) stack concept for the assembly of photolithographically fabricated microfluidic components is presented and discussed. The system uses silicon-based micropumps and simple planar structures which mimic standard elements of conventional flow systems. Detection is provided either by solid state electrochemical sensors or small volume optical detection. The general advantages of using micromachined flow manifolds for microchemical analysis are addressed. The particular benefits to be derived from this an approach compared with other assembly methods are also examined.

Advanced deep reactive ion etching (ADRIE) is a new tool for the fabrication of bulk micromachined devices. Different sensors and actuators which use ADRIE alone or combined with other technologies such as surface micromachining of silicon are presented here. These examples demonstrate the potential and the design freedom of this tool, allowing a large number of different shapes to be patterned and new smart devices to be realized.

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