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Summary The genetic data on two new families with angiokeratoma corporis diffusum are recorded. The first pedigree extends over five generations. Six males are known to be affected in the three most recent generations, and possibly three more in the two previous ones. The mode of inheritance is consistent with a sex‐linked gene. This is confirmed by the occurrence of colour blindness and informative Xga findings in one section of the family, suggesting that the angiokeratoma locus may lie between those for Xg and deutan. Prof. C. E. Dent kindly drew our attention to the original probands in family A and Prof. M. 1,. Rosenheim to the one in family B. We should like to thank Dr Ruth Sanger for carrying out the Xga studies and for her comments on the results, and Mr D. P. Greaves for the ophthal‐mological assessments. Dr P. C. Farrant invited us to see case IV. 38 in family A and Prof. A. G. Watkins informed us about V. 16. We are also grateful to a number of other doctors and hospitals who have supplied us with additional information.

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We used community partnerships to develop an integrated science-learning program focused on two groups of learners-university and middle school (MS) students-to increase students' interest and confidence in science as well as motivation to pursue science. Key program elements include a university course for undergraduate and graduate students, university student-led weekly afterschool clubs held at local middle schools (mostly Title I), and a capstone museum science festival led by university and MS students. Across nine course offerings, 78 university students conducted 25 clubs at seven middle schools and engaged at least 240 MS students. The capstone science festival engaged ~1,200 public participants across six events. We evaluated the program in two phases. Quantitative and qualitative assessments show that university students enjoyed the course and increased their ability to describe complex scientific phenomenon to youth. Middle school students reported significant increases in science interest, science understanding, and understanding scientists (1st evaluation phase); and increased interest in a career in science and in their perception of others seeing them as a scientist (2nd phase). Consistent with prior research, overall we found an increase in interest and understanding of science, science identity, and interest in future science careers for MS students.