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Summary: Meningoencephalitis proved to be due to an amoeba (Naegleria) has been diagnosed in Great Britain for the first time. The first patient (a boy of 2) survived longer than any previously recorded cases, but in spite of early diagnosis and treatment he died 15 days after the onset of meningeal symptoms.Two other children who were exposed to the same possible source of infection (a warm, muddy puddle) had similar symptoms and developed mild meningitis. A naegleria was isolated from the cerebrospinal fluid of one of them. Both recovered after treatment with amphotericin.

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The doctor says she's got a bad heart," said a mother, " but it's us who suffer, not her." How much does the family suffer? Firstly, we wanted to determine whether congenital heart disease has an appreciable impact on the family of the affected child. Secondly, if it has, to assess how the impact is influenced by the cardiac disorder, by the characteristics of the family, and by medical management. The aim was, so far as is possible, to check clinical impressions with hard facts and statistically valid data-" to measure the measurable and make measurable the immeasurable." Material and Methods The study was based on 100 randomly selected children with congenital heart disease of all ages from infancy onwards. They were under the care of many family doctors and several consultants. Thirty-nine lived in Bristol, the remaining 61 in other parts of the Southwestern Region. The diagnoses, operations, and deaths are summarized in Table I. TABLE I.-Cardiac Malformation in 100 Children Diagnosis No.

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