Kata kunci: diagnostik dini, infeksi virus dengue, antigen NS1, anak

BACKGROUND: Dengue infection is one of the problems in the national health sector in Indonesia because the incidence and mortality in Indonesia due to dengue infection is still very high. In 2005 Indonesia became the highest contributor to dengue infection in Southeast Asia (53%) with 95.270 people and 1.298 deaths. AIM: This study aims to analyse differences in angiopoietin-2 levels in dengue hemorrhagic fever (DHF) with and without shock. METHODS: This study was a consecutive sampling design with the research subject was obtained based on the order of admission to the hospital — the serum Angiopoietin-2 levels using the ELISA method. The statistical test used is the independent t-test. The value of p < 0.05 was said to be statistically significant. RESULT: The result showed that the mean of Angiopoietin-2 levels in DHF patients with shock was higher than in DHF (p < 0.05). CONCLUSION: This study concluded that there was a difference in the average level of Angiopoietin-2 among DHF patients with shock compared to without shock.

Berat badan lahir bayi merupakan salah satu penanda asupan gizi ibu selama kehamilan. Zink adalah salah satu mikronutrien penting untuk fungsi sejumlah enzim dan hormon pertumbuhan. Defisiensi zink dan kenaikan berat badan selama kehamilan yang kurang dari normal dapat menyebabkan berat badan lahir rendah. Tujuan: Untuk mengetahui hubungan kadar zink dan kenaikan berat badan ibu selama kehamilan dengan berat badan lahir bayi. Metode: Desain penelitian ini adalah cross-sectional, observasi pada 39 orang ibu yang pada waktu hamil trimester III pernah datang memeriksakan kehamilannya dan tercatat telah melahirkan di RSUD Curup, Kabupaten Rejang Lebong, Provinsi Bengkulu. Kadar zink diperiksa di Balai Laboratorium Kesehatan Sumatera Barat dengan immunoassay, dan kenaikan berat badan ibu hamil diperiksa dengan mengukur selisih berat badan trimester III dengan sebelum kehamilan. Hasil: Didapatkan rerata kadar zink ibu hamil aterm adalah 60,35±39,16 μg/dL; rerata kenaikan berat badan ibu hamil aterm adalah 11,59±5,95 kg; dan rerata berat badan lahir bayi 3002,56±580,60 gr. Terdapat korelasi sangat kuat antara kadar zink dan kenaikan berat badan ibu hamil aterm dengan berat badan lahir bayi, dengan nilai p=0,000 dan r=0,879. Simpulan: Nilai korelasi (r) yang positif menunjukkan bahwa semakin tinggi kenaikan berat badan ibu hamil, maka diperkirakan berat badan bayi yang dilahirkan semakin besar, dan sebaliknya.

No abstract

Latar belakang. Kejadian infeksi virus dengue (IVD) meningkat di Sumatera Barat pada beberapa tahunterakhir. Bahkan, terjadi pada anak usia kurang dari satu tahun. Bayi mempunyai karakteristik klinik yangunik dan tidak banyak penelitian mengenai hal ini di Indonesia.Tujuan. Mengetahui profil klinis, laboratorium, dan serologi infeksi virus dengue pada bayi yang dirawatdi RSUP Dr. M Djamil Padang dari tahun 2012-2014Metode. Seri kasus menggunakan data rekam medik bayi yang dirawat di RSUP Dr M Djamil Padang dari1 Januari 2012 sampai 31 Desember 2014. Data mencakup usia, jenis kelamin, hari demam saat diagnosis,gejala dan tanda klinis, serta laboratorium.Hasil. Duabelas bayi dengan usia termuda 3 bulan dan usia terbanyak 5 bulan (5/12). Muntah merupakangejala tambahan yang paling banyak ditemukan (9/12), diikuti oleh ptekie dan syok (6/12), serta batuk(5/12). Infeksi primer didapatkan pada 8/12 bayi.Kesimpulan: Rerata usia dan kelompok usia terbanyak 5 bulan. Muntah merupakan gejala yang banyakditemui, diikuti, petekie, batuk dan syok sebagian besar merupakan infeksi primer.

*Departemen Ilmu Kesehatan Anak Fakultas kedokteran Universitas Andalas/RSUP dr. M. Djamil, Padang Latar belakang. Sepsis neonatorum awitan dini (SNAD) merupakan penyebab utama kesakitan dan kematian pada neonatus. Adanya gejala klinis yang tidak spesifik dan keterbatasan sarana pemeriksaan penunjang masih merupakan masalah dalam diagnosis sepsis. Sistem skoring hematologi (SSH) dapat digunakan sebagai metode deteksi awal SNAD. Tujuan. Mengetahui apakah sistem skoring hematologi (SSH) dapat digunakan dalam diagnosis awal SNAD. Metode. Penelitian ini merupakan penelitian cross sectional dan uji diagnostik pada bayi dengan risiko dan diduga sepsis neonatorum awitan dini yang dirawat di NICU/Perinatologi RSUP Dr. M Djamil Padang dari bulan Oktober 2016 hingga Juni 2017. Diagnosis sepsis ditegakkan berdasarkan pemeriksaan klinis dan biakan darah. Sistem skoring hematologi terdiri delapan parameter hematologis. Hasil. Subjek penelitian 78 pasien, terdiri dari tidak sepsis 30 orang (38%) sepsis klinis 28 orang (36%) dan terbukti sepsis 20 orang (26%). Nilai SSH tidak sepsis lebih rendah dari kelompok sepsis klinis dan terbukti sepsis. Tidak terdapat perbedaan yang bermakna nilai SSH kelompok terbukti sepsis dan sepsis klinis. Nilai SSH ≥2 memiliki nilai sensitifitas 100%, spesifitas 25,8 % dalam mendiagnosis sepsis (bakteremia ) pada bayi dengan dugaan SNAD. Kesimpulan. Sistem skoring hematologi ini dapat digunakan sebagai metode deteksi awal sepsis neonatorum awitan dini, terutama di rumah sakit dengan sarana pemeriksaan penunjang terbatas. Sari Pediatri 2018;20(1):17-23Kata kunci: sepsis neonatorum, sistem skoring hematologi, diagnosis awal The Role of A Hematology Scoring System in Early Onset Neonatal Sepsis DiagnosisRanti Adriani,* Eny Yantri,* Rinang Mariko* Background. Early onset neonatal sepsis (EONS) is a major cause of neonatal morbidity and mortality. Non-specific clinical symptoms and limited investigation facilities are some of the problems in the management of sepsis. The hematological scoring system can be used as an early detection tool for EONS. Objective. The purpose of the study is to evaluate whether a hematological scoring system can be useful in early diagnosis of EONS Method. This study is a cross-sectional study and diagnostic test in infants with risk and suspected EONS treated at NICU/Neonatology Department Perinatology Dr. M. Djamil Hospital in Padang, from October 2016 through June 2017. The diagnosis of sepsis is based on clinical examination and blood culture results. Results. Subjects were 78 patients, consisting of 30 (38%) as nonsepsis, 28 (36%) as clinical sepsis and 20 (26%)were proven to have sepsis. Hematologic scores in non-sepsis were lower compared to the clinical sepsis and proven sepsis groups. There were no significant differences in hematologic score of proven sepsis and clinical sepsis. The score of ≥2 on hematologic scoring system had 100% sensitivity, 25,8 % specificity for diagnosis of bacteremia in infants at risk and suspected EONS. Conclusion. This hematological scor...

BACKGROUND: Dengue virus infection is an infectious disease caused by the dengue virus and transmitted by the Aedes aegypti mosquito. Dengue virus (DEN-V) consists of 4 serotypes, namely DEN-1, DEN-2, DEN-3, and DEN-4. The most feared result of DHF is death. Death in children is caused by hypovolemic shock due to plasma leakage from intravascular to extravascular space due to endothelial dysfunction. AIM: This study aims to analyse difference in sVE-Cadherin levels in Dengue Hemorrhagic Fever (DHF) with and without shock. MATERIAL AND METHODS: The method of taking samples is consecutive sampling, namely the research subjects obtained based on the order of entry in the hospital with a comparative cross-sectional design. From the results of the calculation using the sample formula, the sample size for each group is set at 32 people. So that the total sample size used for both groups is 64 people. The serum sVE-Cadherin levels using the ELISA method. The statistical test used is the independent t-test. The value of p < 0.05 was said to be statistically significant. RESULTS: The result showed that there was no difference in mean sVE-Cadherin levels between DHF patients with shock and without shock (p > 0.05). CONCLUSION: This study concluded that there was no difference in mean of sVE-Cadherin level in DHF patients with shock and without shock.

<div><table cellspacing="0" cellpadding="0" align="left"><tbody><tr><td align="left" valign="top"><p align="center"><strong><em>Abstract</em></strong></p><p align="center"><strong><em> </em></strong></p><p><em>Stunting is a chronic malnutrition problem characterized by height for age which is &lt;-2 SD according to the median standard of child growth. Stunting causes poor quality of human resources, which will reduce productivity. </em><em>T</em><em>he factor causing the problem of stunting In Tools AtPagambiran Health Center, Padang City is the lack of clean water sanitation. The purpose of this study was to determine the relationship between the nutritional status of the mother, the height of the mother, and the mother's knowledge of the incidence of stunting in toddlers at the Pagambiran Health Center, Padang City.This research is an observational analytic study with a cross-sectional design. This research was conducted at the Pagambiran Health Center in Padang City with 3457 populations in November 2021-December 2022. The research sample was 174 mothers and children aged 24-59 months. Sampling using Stratified Random Sampling and Simple Random Sampling. Data collection used a questionnaire and the MCH handbook. The statistical tests used are Chi-square and Logistic Regression.The results of the univariate study found that 55 mothers (31.6%) had a history of chronic energy deficiency, and 12 mothers (6.9%) had a height &lt; 150 cm. The results of the bivariate study using chi-square analysis obtained the p-value of each variable, namely the mother's nutritional status (p=0.005) and mother's height (p=0.018). The study concludes that there is a relationship between the mother's nutritional status and the mother's height in the incidence of stunting in toddlers at the Pagambiran Health Center, Padang City.</em> <em>Researchers suggest that counseling related to stunting can be carried out for pregnant women and prospective brides as an initial preventive measure.</em></p><p><em> </em></p></td></tr></tbody></table></div><strong><em>Keywords: <strong><em>Chronic Energy Deficiency, Mother's Height, Stunting.</em></strong></em></strong>