Renate Spohn scite author profile

A panel of newly isolated murine monoclonal antibodies is described which are specific for the Nef protein of the human immunodeficiency virus type 1 (HIV-1). Epitope mapping using recombinant Nef-related proteins, synthetic peptides and lipopeptides showed 3 independent antigenic determinants located within the regions of amino acids 83-93, 175-190 and 86-166 of the Nef protein. None of the monoclonal antibodies reacted with recombinant Nef proteins of HIV-2.

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Renate Spohn

Synthetic lipopeptide adjuvants and Toll-like receptor 2—structure–activity relationships

Immunological variation and immunohistochemical localization of HIV-1 Nef demonstrated with monoclonal antibodies

B-cell epitopes of the Nef protein

Fully automated synthesis of peptides on polyethylene pins

Fine mapping of HIV-1 Nef-epitopes by monoclonal antibodies

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