Thymosine β11, a peptide structurally very similar to the known thymosine β11, was recently isolated from trout spleen and synthesized by the solid phase method using the p-benzyloxybenzyl alcohol/polystyrene/divinylbenzene resin, Nα-Fmoc-amino acids and those with tert-butyl or Boc side chain protection. All couplings are performed with the DCC reagent. The peptide is purified by a combination of gel chromatography and preparative HPLC.
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