Adesão à terapêutica antirretroviral de pessoas vivendo com HIV/aids em um município do interior paulista Adhesión a la terapia antirretroviral de personas viviendo con VIH/SIDA en un municipio del interior ABSTRACTObjective: To assess adherence to antiretroviral drugs by people living with HIV/AIDS and identify its association with sociodemographic and clinical variables. Methods:Cross-sectional analytical study using a sociodemographic instrument and CEAT-HIV, with data collected in the period from 2014-2015.Results: A 75.0% was identified as having a good/proper adhesion. It was found that individuals between ages 40 and 59 (p = 0.029) and with morethan eight years of formal education (p = 0.043) had a higher level of compliance, as well as those diagnosed with HIV/AIDS for more than 10 years (p = 0.002), CD4 count >350 cells/mm3 (p<0,001) and an undetectable viral load (p=0,025). Conclusion:In this study, a good adhesion between the subjects was identified and it was observed that individuals of older age, higher level of education, delayed diagnosis, high CD4 cell counts and undetectable viral load were associated with higher treatment adherence.Keywords: Medication adherence. Antiretrovirals. HIV. Nursing. Nursing care. RESUMO Objetivo: Avaliar a adesão aos antirretrovirais de pessoas vivendo com o HIV/AIDS e identificar sua associação com variáveis sociodemográficas e clínicas.Métodos: Estudo analítico transversal que utilizou instrumento sociodemográfico e o CEAT-HIV, com dados coletados no período de 2014 a 2015.Resultados: Identificou-se 75,0% com grau de adesão bom/adequado. Verificou-se que os indivíduos com idade entre 40 e 59 anos (p=0,029) e com mais de oito anos de estudo (p=0,043) obtiveram maior grau de adesão, assim como aqueles com diagnóstico de HIV/AIDS há mais de 10 anos (p=0,002), contagem de TCD4 >350 células/mm 3 (p<0,001) e carga viral indetectável (p=0,025). Conclusão:Nesse estudo, identificou-se uma boa adesão entre os sujeitos e observou-se que indivíduos de maior faixa etária, maior grau de escolaridade, maior tempo de diagnóstico, elevada contagem de células TCD4 e carga viral indetectável estiveram associados a uma maior adesão ao tratamento.Palavras-chave: Adesão à medicação. Antirretrovirais. HIV. Enfermagem. Cuidados de enfermagem. RESUMEN Objetivo: Evaluar la adherencia a los medicamentos antirretrovirales para las personas que viven con el VIH/SIDA e identificar su asociación con variables sociodemográficas y clínicas.Métodos: Estudio transversal analítico utilizando instrumento sociodemográfico y CEAT-VIH, con los datos recogidos desde 2014 hasta 2015.Resultados: Se identificó un 75,0% con el grado de buena adherencia/adecuada. Se encontró que los individuos con edades comprendidas entre los 40 y los 59 años (p = 0,029) y más de ocho años de estudio (p = 0,043) tuvieron mayor nivel de cumplimiento, así como las personas diagnosticadas con VIH/SIDA durante más de 10 años (p = 0,002), recuento de CD4> 350 células/mm3 (p <0,001) y la carga viral indetectable (p = 0,025). Concl...

Objective: To identify and explore the dimensions of the difficulties faced by people living with HIV/Aids in the disease management. Methods: A qualitative, descriptive, exploratory study was developed in Specialized Care Services, with 26 patients. The recorded interviews were transcribed, and then processed and analyzed by means of descending hierarchical classification. Findings were based on the collective subject discourse. Results: Five classes were obtained: "Intrafamilial prejudice and its impact on coping with the disease"; "Social prejudice: macro environment impacts"; "Difficulties in managing the risk of HIV/Aids transmission and its implications on partnerships", "Maintenance of high rates of HIV/ Aids treatment adherence: qualifying the service" and "Quality of life promotion for people living with HIV/Aids". Conclusion: The difficulties experienced go far beyond the disease, with central, intimate aspects, and are linked to prejudice, which hinders their personal, professional and affective development, expanding into abstract macro-concepts such as quality of life. ResumoObjetivo: Identificar e explorar as dimensões das dificuldades enfrentadas por Pessoas Vivendo com HIV/Aids no manejo da doença. Métodos: Estudo descritivo, exploratório, de abordagem qualitativa desenvolvido em Serviços de Atendimento Especializado, com 26 pacientes. As entrevistas gravadas foram transcritas e posteriormente, processadas analisadas pela Classificação Hierárquica Descendente. Os achados foram fundamentados no Discurso do Sujeito Coletivo. Resultados: Obteve-se cinco classes: "O preconceito intrafamiliar e seu impacto no enfrentamento da doença"; "Preconceito social: os impactos do macroambiente"; "As dificuldades em gerenciar o risco de transmissão do HIV/Aids e as implicações em parcerias", "A manutenção de altas taxas de adesão ao tratamento do HIV/Aids: qualificando o serviço" e " Promovendo a qualidade de vida em pessoas vivendo com HIV/Aids". Conclusão: As dificuldades experienciadas vão muito além da doença, tomando aspectos íntimos, centrais ligadas ao preconceito, que impede seu desenvolvimento pessoal, profissional e afetivo expandindo-se a macro-conceitos abstratos como qualidade de vida.

This study aimed to identify the factors that interfere in maintaining safe sex. Data were collected through individual interviews with 11 HIV/AIDS patients living with HIV-negative partners, under clinical treatment at a specialized AIDS clinic. Analysis was based on Prose analysis by André (1983). The concept of vulnerability was used as a theoretical reference framework. The sexual prevention of HIV/AIDS for the non infected partner constitutes one of the largest challenges for the serodiscordant couples, because men and women accept condoms differently. The greater motivation towards condom use among serodiscordant couples does not eliminate the difficulties to use them for maintaining safe sex. The serodiscordant couples deserve specific assistance, and the preventive strategies should contemplate the cultural and psychosocial aspects that constitute important aspects of mixed-status partner vulnerability.

Hornet users have insufficient knowledge about HIV prevention measures, especially when discarding the male condom. The relationships established through the application are permeated by high individual vulnerability and behaviors that have potential exposure to the risk of HIV infection.

After more than one century since its discovery, Chagas disease is still extremely prevalent in 21 Latin American countries. Chagas disease is one of the most concerning public health problems in Latin America; the overall cost of CD treatment is approximately 7 billion United States dollars per year and it has a strong social impact on populations. Little progress has been made regarding the access to diagnosis and treatment at the primary health care level, calling into question the current policies to ensure the right to health and access to essential medications. In this article, diverse dimensions of access to treatment for Chagas disease are reviewed, illustrating the present state of benznidazole medication in relation to global production capacity, costs, and needs. The findings are based on an investigation requested by Médecins Sans Frontières Brazil through a consultancy in 2015, aiming to estimate the current costs of benznidazole production.

Despite notable scientific and medical advances, broader political, socioeconomic and behavioural factors continue to undercut the response to the COVID-19 pandemic1,2. Here we convened, as part of this Delphi study, a diverse, multidisciplinary panel of 386 academic, health, non-governmental organization, government and other experts in COVID-19 response from 112 countries and territories to recommend specific actions to end this persistent global threat to public health. The panel developed a set of 41 consensus statements and 57 recommendations to governments, health systems, industry and other key stakeholders across six domains: communication; health systems; vaccination; prevention; treatment and care; and inequities. In the wake of nearly three years of fragmented global and national responses, it is instructive to note that three of the highest-ranked recommendations call for the adoption of whole-of-society and whole-of-government approaches1, while maintaining proven prevention measures using a vaccines-plus approach2 that employs a range of public health and financial support measures to complement vaccination. Other recommendations with at least 99% combined agreement advise governments and other stakeholders to improve communication, rebuild public trust and engage communities3 in the management of pandemic responses. The findings of the study, which have been further endorsed by 184 organizations globally, include points of unanimous agreement, as well as six recommendations with >5% disagreement, that provide health and social policy actions to address inadequacies in the pandemic response and help to bring this public health threat to an end.

Objective: to identify factors associated with occupational exposure to biological material among nursing professionals. Method: a cross-sectional study was conducted in a high complexity hospital of a city in the state of São Paulo, Brazil. Nursing professionals were interviewed from March to November 2015. All ethical aspects were observed. Result: among the 226 professionals interviewed, 17.3% suffered occupational exposure to potentially contaminated biological material, with 61.5% being percutaneous. Factors such as age (p=0.003), professional experience in nursing (p=0.015), and experience at the institution (p=0.032) were associated with the accidents with biological material. Conclusion: most accidents with biological material among nursing professionals were percutaneous. Age, professional experience, and experience at the institution were considered factors associated with occupational exposure.

ABSTRACT:The aim of this study was to evaluate the social support for people with AIDS. It was a cross-sectional study, with 215 outpatients at a University Hospital in Northeastern Brazil. Data were collected from August to December 2012, through interviews, using a Socio-demographic and Clinical Form and a Social Support Scale for People Living with HIV/AIDS. Statistical Package for the Social Science was used for data analysis. Results showed that average scores of social emotional and instrumental support were satisfactory and not influenced by sex (p=0.954; p=0.508), education (p=0.756; p=0.194), marital status (p=0.076; p=0.446) and length of antiretroviral therapy (p=0.480; p=0.120). People diagnosed for less than three years had more instrumental support (p=0.048) than those diagnosed over three years (p=0.370). Neighbors, employers and health professionals provided less support. The conclusion was that people with AIDS have satisfactory social support, especially from friends and family not living in the same household. DESCRIPTORS: APOYO SOCIAL DE LAS PERSONAS QUE VIVEN CON SÍNDROME DE INMUNODEFICIENCIA ADQUIRIDARESUMEN: Este estudio objetivó evaluar el apoyo social a personas con SIDA. Estudio transversal con muestra de 215 pacientes ambulatorios de un hospital universitario del nordeste de Brasil. Los datos recolectados entre agosto y diciembre de 2012, a través de entrevistas utilizando el formulario sociodemográfico y clínico y la Escala de Apoyo Social para las Personas que Viven con VIH/SIDA. El Statistical Package for the Social Science fue utilizado para análisis de datos. Los resultados evidenciaron que las puntuaciones medias de apoyo social emocionales e instrumentales fueron satisfactorios, y no influenciados por el sexo (p=0,954; p=0,508), educación (p=0,756; p=0,194), estado civil (p=0,076; p=0,446) y tiempo de terapia antirretroviral (p=0,480; p=0,120). Las personas diagnosticadas en menos de tres años tenían más apoyo instrumental (p=0,048) que los diagnosticados hace más de tres años (p=0,370). Los vecinos, jefe y profesionales de salud proporcionaban menos apoyo. Se concluyó que personas con SIDA tienen un apoyo social satisfactorio, principalmente por parte de amigos y familiares que no viven en el mismo hogar.DESCRIPTORES: Síndrome de inmunodeficiencia adquirida. VIH. Apoyo social.