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New tellurated schiff bases were synthesized by the reaction of the corresponding mercurated Schiff  bases compounds A1-A3 with tellurium tetrabromide in 1:1 mole ratio and  that  gave organyltellurium tribromides  A4-A6.  On the other hand, when mercurated schiff bases and tellurium tetrabromide brought  together in 2:1 mole ratio gave diorganyltellurium dibromides compounds A10-A12 followed by reduction with hydrazine hydrate gave new diorganyl tellurides A13-A15.  Reduction of compounds A4-A6 by  hydrazine hydrate gave new ditellurides A7-A9.  All compounds were characterized by elemental analysis, IR, 1H , 13C NMR, HSQC-NMR and mass spectra.  Invitro anti-tumor bioactivity of some compounds were tested.

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Quantum mechanical calculations of geometries, energies and vibrational frequencies of organic mercury and tellurium compounds containing azomethine group, molecules a1-a5 and containing azo group, molecules a6-a10 have been undertaken using density functional theory. The optimized geometrical parameters such as bond lengths, bond angles and dihedral angles showed that only organomercuric compounds have planer structures. The calculation of the total energy and HOMO-LUMO energy gap were showed that organotellurium compounds have higher reactivity than the corresponding organomercuric compounds. As well it showed the HOMO orbitals are localized mainly on tellurium, nitrogen and bromine atoms moieties, while the LUMO of π nature are mostly located on the phenyl ring. The calculated vibrational frequencies of molecules a1 and a7 are in good agreement with experimental frequencies with correlation coefficient r 2 value is 0.9875 and 0.9987, respectively.

T HE reaction of L-Cysteine with 2-hydroxy naphthaldehyde and 2-hydroxy benzaldehyde yields novel bidentate ligands (2R,4R)-2-(2-hydroxynaphthalen-1-yl) thiazolidine-4carboxylic acid (L 2) and (2R,4R)-2-(2-hydroxyphenyl) thiazolidine-4-carboxylic acid (L 1), respectively, which can be characterised based on spectral and physical data. Synthesis of complexes with the formula ML 2 .XH 2 O is done via the reaction of L 1 and L 2 with Cu(II), Fe(II) and VO(II) in molar ratio of 1:2 pertaining to metal to ligand. Based on mass and UV/ visible spectra, IR, flame atomic absorption, magnetic susceptibility as well as thermal analysis of metal complexes, we can conclude that the ligands behave as a bidentate and help to identify proper structure pertaining to complexes. Then, screening of the synthesized compounds is carried out to determine their antibacterial activity against Pseudomonas aeruginosa and Streptococcus epidermis. All compounds showed bio-activity with iron complexes possessing the highest efficiency. The density functional theory at the B3LYP level of theory was employed to calculate the geometry optimisation pertaining to molecular structure as well as energies of ligands and its associated complexes. The observations of the theoretical calculations were in line with the outcomes of the experiment.