Ipomoea staphylina plant ethanolic extract was subjected to preliminary qualitative phytochemical and quantitative GC-MS analysis with analyzing its antibacterial activity by the standard method. The preliminary qualitative phytochemical analysis is done by standard procedure and quantitative GCMS analysis is done by subjecting it to GC Model: Thermo Trace GC Ultra model instrument. Antibacterial activity is done by the standard agar well diffusion method. Preliminary qualitative phytochemical analysis for pet ether and chloroform extract confirms for fewer phytochemicals but ethanolic extract confirms for the presence of alkaloids, saponins, flavonoids, steroids, glycosides, phenols and sterols. GC-MS analysis of I. staphylina ethanolic leaf extract confirms the presence of 79 compounds, out of these 24 compounds were unknown and 55 compounds were known for its medicinal properties. The antibacterial experiment revealed that I. staphylina plant ethanolic extract has appreciable antibacterial activity in all tested concentrations against selected bacterial pathogens but comparably less with the standard ciprofloxacin used but pet ether and chloroform extract showed negligible antibacterial activity. I. staphylina plant could be exploited as a valuable source of antibacterial agent enriching with known antibacterial compounds.
Objective: Pavetta crassicaulis Bremek. (F: Rubiaceae) plant extracts were subjected to anti-inflammatory experiment by using carrageenin-induced rat hind paw edema method.Methods: Groups of 5 rats of both sexes (pregnant females excluded) were given a dose of the extract. After 1 h, 0.1 ml, 1% carrageenan suspension in 0.9% NaCl solution was injected into the subplantar tissue of the right hind paw. Paw volume was measured plethysmometrically at 0 h and 3 h after carrageenin injection.Results: Anti-inflammatory experiments revealed that, the leaf and flower ethanolic extract of the P. crassicaulis Bremek. plant shown excellent anti-inflammatory and its extracted pure compounds, 2-tert-butyl-4,6-bis(3,5-di-tert-butyl-4-hydroxybenzyl)phenol and 4H-pyran-4-one,2,3-dihydro3,5- dihydroxy-6-methyl- is a pure compound isolated from the Pavetta crassicaulis flower extract. showed excellent anti-inflammatory activity compared with the standard.Conclusion: P. crassicaulis Bremek. leaf and flower could be exploited as a valuable source of anti-inflammatory agent for the pharmaceutical industry.
Olea dioica is a medicinal angiospemic tree of Western Ghats India. Roots of the plant used for cancer and snake bite treatment in siddha and bark, fruit paste is used in the treatment of rheumatism; decoction of the bark is used to wash old wounds and given in fever. Plant material was collected from different forest types of Western Ghats, Karnataka were air dried subjected for soxhlet extraction and these extracts were subjected for preliminary phytochemical and GC-MS analysis using standard procedures. The results obtained was compared with the different forest types of Western Ghats revealed that the Sagara forest area showed higher yield of crude extract, with higher secondary metabolites compared to the Chakra and Kigga forest area. which may be due to the influence of climatic factors like stress, temperature, rainfall, humidity, wind speed, light intensity, the supply of water, minerals, and CO 2 etc.
Roem & Schult. plant ethanolic extract were subjected to Antioxidant, cytotoxic and Ipomoea staphylina nutritive experiment by using standard method. Ethanolic extract of was Materials and Methods: I. staphylina investigated for antioxidant experiment by using DPPH, ABTS, superoxide radical scavenging, Hydroxy radical scavenging, Metal chelating assays. Cytotoxic experiment is done by trypan blue exclusion test using DLA and EAC cancer cells. Nutritive value is performed by double acid digestion followed by Atomic absorption spectroscopy. Results: Antioxidant experiment revealed that plant ethanolic extract has excellent antioxidant activity in I. staphylina all tested experiments but comparably less with the standards used. plant ethanolic extract has negligible I. staphylina toxicity compared to the standard curcumin used. From nutritive value experiment it is revealed that plant I. staphylina has high iron content with rich macro and micronutrients. plant could be exploited as a Conclusion: I. staphylina valuable source of antioxidant agent enriching with nutrients.
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