~ ____________Ahstrnct. The main purpose of this investigation was to study the assimilation of cyanocobalamin from fish. For this reason rainbow trout were injected with "'Co-vitamin B,, and sacrificed 2 to 3 weeks later. The radioactivity was found to be evenly distributed in the muscle mass. In contrast to findings in birds and mammals the liver contained on the average less radioactivity than did the kidneys, head, skin, and muscle mass. The radiolabeled fish was ingested by three healthy subjects in 50to 300-g portions and the absorption measured by the stool excretion method. The study shows that from an average of 2.07 p g of vitamin B,, (50 g of fish), 4.05 p g (100 g). 9.2 pg (200 g), and 13.3 pg (300 g) the assimilation of cobalamin averaged 0.87, 1.55. 3.90, and 3.98 pg, respectively. In two of the subjects, an upper limit of absorption was reached, while in one it was still climbing. A standard urinary excretion test using 100 g of fish, eaten by healthy subjects and by patients who presented with low serum vitamin B,, levels, showed very low absorption values after the fish and after the crystalline radiocyanocobalamin in patients with pernicious anemia. Subnormal assimilation of cobalamin from the fish with normal absorption of crystalline radio-B,, was noted in subjects with simple gastric achlorhydria and in patients who had undergone partial gastrectomy. 480 0037-972718 llO80480-05$0 1 .OO/O
Variations in growth rates of Dover sole (Microstomus pacificus) off Astoria and Brookings, and of English sole (Parophrys vetulus) off Astoria and Coos Bay, Oregon were studied by means of increments between annuli on scales and interoperculum bones for Dover and English sole, respectively. Age‐specific growth rates of both species were statistically different among years. The maximum variation for Dover sole was 19% of the mean growth rate for the period 1958–1975. English sole growth varied as much as 17% from the mean growth between 1961 and 1974. Dover and English sole showed the same good or poor years for growth simultaneously among all locations. The growth increments were significantly greater for Dover sole captured off Astoria than for Dover sole captured off Brookings. There were no significant growth differences for English sole by location. Dover sole off Astoria had a general long‐term increase in growth rate between 1958 and 1966 followed by a gradual decrease through 1969. Large fluctuations in the rate occurred through the mid‐1970s. A similar long‐term trend occurred for English sole but was less apparent due to the shorter time series of data. The growing season for English sole begins in March and probably extends through September. The most rapid growth occurs during May and June. For these months annual variations in a continental shelf temperature index are significantly and negatively correlated with annual fluctuations in growth increments of both species. Although variations in the May and June upwelling index were not significantly correlated with annual fluctuations in growth, long‐term trends of these two factors appear to be related. Growth does not seem to be associated with stock density changes.
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