The use of medicinal plants is increasing due to the search for alternative resources to treat diseases such as hypertensions and infection. Along with the development in science, preventive action should take place to prevent our body from suffering from these diseases. This can be done by increasing the human immune status with immunomodulatory agents. Binahong empirically have benefits for wound healing. The purpose of this research was to investigate the immunomodulatory effect of ethanolic extract of binahong leaves. The non-specific modulatory effects of the ethanolic extracts of binahong leaves on the immune systems were measured based on phagocytosis index and phagocytosis capacity. Tests were conducted on strain Balb/C male mice at the age of 6-8 weeks. Mice were administered orally with the extract of binahong leaves (doses of 25, 50, 75 mg/kgBW) for 14 days. The test results with the index parameters and macrophages phagocytosis capacity at doses of 50 and 75 mg/kgBW did not significantly increased when compared with the controls. From these results, we concluded that the ethanolic extract of binahong leaves with a dose of 25, 50 and 75 mg/kgBW cannot significantly the activity of macrophages by phagocytosis index parameters and phagocytosis capacity significantly.
Jamu is still the choice of Indonesian people as an alternative to modern medicine until now. As a cultural heritage of the Indonesian, jamu is still very popular from the west to the east of Indonesia. The enthusiasm of the Indonesian in consuming jamu has encouraged many traditional medicine industries to produce jamu with many kinds of claim. Jamu "X" is claimed to help maintain body health. This research was conducted to determine the total flavonoid content in jamu "X" calculated as rutin by UV-spectrophotometric method with aluminum chloride (AlCl3) reagent. Jamu "X" is a product with new formula that is expected to be marketed soon. The determination of the maximum absorbance wavelength of rutin was carried out at a wavelength of 400-800 nm and the resulting maximum absorbance wavelength of rutin was 416.5 nm. The determination of total flavonoid calculated as rutin determined using a linear regression equation from the rutin standard. The linear regression equation was determined from a rutin standard curve series with 10; 12.5; 15; 17.5 and 20 g/ml, respectively and the linear regression equation obtained y = 0.0275x + 0.093. The results of the determination of rutin in the jamu "X" were 1.474%; 1.474% and 1.469% with an average value of 1.472%.
Jamu pegal linu merupakan obat tradisional yang banyak dikonsumsi oleh masyarakat karena memiliki banyak manfaat. Bahan Kimia Obat (BKO) sering ditambahkan pada jamu pegal linu untuk menambah khasiatnya. BKO yang banyak ditambahkan dalam sediaan jamu adalah ibuprofen, natrium diklofenak dan fenilbutazon. Tujuan dari penelitian ini adalah mengidentifikasi kandungan bahan kimia obat pada jamu pegal linu di wilayah Magelang sehingga menjadi referensi keamanan jamu. Sampel adalah 6 (A, B, C, D, E, F) jamu pegal linu yang diperoleh dari toko jamu di wilayah Magelang. Identifikasi BKO dilakukan dengan Kromatografi Lapis Tipis (KLT) menggunakan fase diam silika gel 60 F254, fase gerak kloroform:etanol (8:1), etil asetat:n-heksan (3:2), etanol:kloroform:aseton (6:4:1) dan dideteksi sinar UV 254 nm. Hasil uji organoleptis menunjukkan bentuk dari semua jamu yaitu serbuk halus dan semuanya memiliki rasa yang pahit, mempunyai bau khas jamu. Sampel C memiliki aroma khas cengkeh. Hasil KLT tidak ditemukan kandungan fenilbutazon dan natrium diklofenak pada seluruh sampel. Sampel E dan F positif mengandung ibuprofen.
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