RESUMOObjetivo: Investigar a associação das doenças crônicas não transmissíveis e fatores sociodemográficos com sintomas de depressão em idosos. Métodos: Foi realizado um estudo transversal com 1.391 idosos cadastrados na Estratégia Saúde da Família. Os dados sociodemográficos e de doenças crônicas não transmissíveis foram coletados pelos agentes comunitários de saúde. A Escala de Depressão Geriátrica abreviada foi utilizada para investigar os sintomas de depressão. Resultados: Aproximadamente 81% referiram ao menos uma doença crônica não transmissível. Os sintomas depressivos foram associados com sexo feminino, doença coronariana, insuficiência cardíaca e acidente vascular cerebral; ≥ 8 anos de estudo e ter companheiro foram protetores. Dentre as doenças crônicas não transmissíveis, as cardiovasculares e as cerebrovasculares têm associação independente com sintomas de depressão. Conclusões: Esses resultados corroboram a hipótese de que a doença vascular seja um fator de risco para o comprometimento encefálico associado à depressão. Evidencia-se o importante papel dos agentes comunitários de saúde, na Estratégia Saúde da Família, com potencial utilidade nas políticas públicas para a saúde mental do idoso. ABSTRACTObjective: To investigate the association between non-communicable chronic diseases and sociodemographic factors with symptoms of depression in elderly. Methods: Transversal study conducted with 1,391 elderly patients registered in the Family Health Strategy. Social--demographic and non-communicable chronic diseases data were collected by community health agents. Geriatric Depression Scale abbreviate was used to investigate symptoms of depression. Results: About 81% of all patients reported at least one non-communicable chronic disease. Symptoms of depression was associated with women, coronary disease, cardiac insufficiency and cerebrovascular accident; education ≥ 8 years and having a companion were shown to be protecting factors. Conclusions: Cardiovascular and cerebrovascular non--communicable chronic diseases are independently associated with depression. These results support the hypothesis that vascular disease is a risk factor for brain impairment associated with depression. This research illustrates the role of community health agents within Family Health Strategy as a tool for public mental health policy.

Resumo Introdução Com o envelhecimento populacional, há o aparecimento de doenças crônicas incapacitantes, entre as quais se destaca a diabetes mellitus (DM). O objetivo do estudo é descrever a prevalência de DM em idosos da Estratégia Saúde da Família (ESF) de Porto Alegre, no Estado do Rio Grande do Sul, de acordo com o tratamento, a adesão medicamentosa e variáveis sociodemográficas e de saúde. Métodos Estudo transversal, realizado em indivíduos acima de 60 anos. Os dados foram coletados por instrumento (dados sociodemográficos, condições de saúde, hábitos de vida e informações de medicamentos). A adesão medicamentosa foi avaliada pela escala de Morisky. Resultados Foram analisados 763 idosos, com idade média de 69,1±7,5 anos, dos quais 63,7% eram do sexo feminino. A prevalência de DM foi de 23,5%, principalmente nas mulheres (27,2%), na faixa etária de 60 a 79 anos (24,6%), nos viúvos (28,4%) e nos que relataram ter cuidador (27,6%). Nas variáveis de saúde, idosos com maior índice de massa corporal (IMC) e aqueles com doença cardíaca apresentaram maior prevalência de DM. A metformina foi o hipoglicemiante que apresentou maior frequência de uso (76,5%). Conclusão A atenção ao idoso diabético vem crescendo nas ESF, por isso este estudo contribuirá para o desenvolvimento de estratégias para melhor atenção a essa população.

Background: Some premature features of immunosenescence have been associated with persistent viral infections and altered populations of T cells. In particular, the inverted T CD4:CD8 ratio has been correlated with increased morbidity and mortality across different age groups. Objective: Here, we investigated the role of persistent viral infections, cognitive and functional states as predictors of inverted CD4:CD8 ratio of older adults in a developing country. Methods: Three hundred and sixty community-dwelling older adults (aged 60-103 years) were recruited. Cognitive function was evaluated by the Instrument of Brief Neuropsychological Assessment and Mini-Mental State Examination inventory. Functional Activities Questionnaire was used to determine activities of daily living. Cytomegalovirus (CMV) and Epstein-Barr virus (EBV) serologies were determined by ELISAs. Peripheral blood was assessed for lymphocyte subsets by flow cytometry (CD4+, CD8+, NK, NKT, B and CD8+CD28-). Results: Fifty-nine individuals were identified with CD4:CD8 ratio <1, and had increased IgG titers to CMV (p < 0.01), but not to EBV, compared to subjects with CD4:CD8 ratio >1. The older adults with inverted CD4:CD8 ratio had impairments in some cognitive dimensions and had more functional disability and dependency (p = 0.01) than subjects with CD4:CD8 ratio >1. The lymphocyte subsets did not vary between groups. The increased CMV-IgG titers alone contributed to 8× higher chance to invert CD4:CD8 T cell ratio (OR 8.12, 95% CI 1.74-37.88, p < 0.01). Conclusion: Our data further indicate the role of CMV on circulating T cells, poor cognition and functional disability/dependency during aging.

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The association of childhood maltreatment and suicide has been extensively examined within the population. Depression figures as a main cause for the elevated suicide rate in advanced ages and is often related to childhood maltreatment. The purpose of the present study was to examine the relationship between childhood maltreatment subtypes and suicide risk, testing geriatric depression as a moderator. This is a cross-sectional study looking at a sample of 449 individuals 60 year s old or older from the Multidimensional Study of the Elderly of Porto Alegre Family Health Strategy, Brazil (EMI-SUS/POA). Childhood maltreatment (Childhood Trauma Questionnaire), geriatric depressive symptoms (Geriatric Depression Scale), and suicide risk (Mini International Neuropsychiatric Interview) were assessed. The subtypes of childhood abuse and neglect were significantly associated with suicide risk. In the multivariate analysis, controlling for age, gender, income, marital status, ethnicity, smoking, and geriatric depression symptoms, all trauma subtypes remained associated with suicide risk with the exception of physical neglect (EA = 3.65; PA = 3.16; SA = 5.1; EN = 2.43; PN = 1.76). The present study showed that childhood maltreatment subtypes predicted suicide risk, and geriatric depression does not directly mediate this relation.

ObjectiveThe aims of this study were to analyze the hematological parameters, the prevalence of anemia and the association between anemia and socioeconomic conditions in an elderly community-based population. MethodsA population-based study was performed as part of the Multidimensional Study of the Elderly in Porto Alegre, Brazil (EMIPOA). An initial total of 1058 community residents aged 60 years and older were interviewed. Of these, 392 agreed to have a physical evaluation and a blood sample was taken from each. The hematological parameters analyzed in the blood samples included the hemoglobin concentration, mean cell volume (MCV), mean corpuscular hemoglobin concentration (MCHC) and red cell distribution width (RDW). The association between the variables and the diagnosis of anemia was assessed using the chi-squared test and a multiple logistic regression model. ResultsThe overall prevalence of anemia was 12.8%. Anemia was present in 13.7% of women and in 10.4% of men. Normocytic normochromic anemia without anisocytosis was the most common type of anemia (46%). The assessment of erythrocyte morphology showed significant differences between anemic and non-anemic individuals (microcytosis = 12% vs. 1.5%, hypochromia = 40% vs. 8.8%, and anisocytosis = 26% vs. 7%). In the analysis of socioeconomic conditions, significant differences were found in respect to age and race. ConclusionThe prevalence of anemia increases with age and is associated with race, microcytosis, hypochromia and anisocytosis. Anemia is not a condition that should be associated only with the aging process, as it may be due to pathological conditions that occur most frequently in this age group. As a result, a diagnosis of anemia warrants adequate clinical attention.

Consumo de nutrientes em idosos residentes em Porto Alegre (RS), Brasil: um estudo de base populacionalConsumption of nutrients among the elderly living in Porto Alegre in the State of Rio Grande do Sul, Brazil: a population-based study

OBJETIVO: Determinar a prevalência de obesidade associada ao consumo de macronutrientes, às alterações do perfil lipídico, à glicemia e à prática de atividade física em idosos. MÉTODOS: Foi realizado estudo transversal com 304 idosos do município de Porto Alegre, RS, Brasil. Medidas antropométricas de peso e altura foram utilizadas para o cálculo do índice de massa corporal (IMC) e foram analisados o perfil lipídico, a glicemia, a ingestão diária de macronutrientes e a prática de atividade física. RESULTADOS: A prevalência de obesidade foi de 30,6%, sofrendo redução com o aumento da idade. As idosas obesas apresentaram maior frequência de hipertrigliceridemia, cujos valores aumentaram conforme o aumento do IMC. Nesse grupo, a prática de atividade física foi menor. Entre os homens, houve maior consumo de proteína na dieta. CONCLUSÃO: Os resultados mostraram que a obesidade é um importante problema de saúde na Região Sul do Brasil, sofrendo influência de fatores socioculturais e econômicos que prejudicam a manutenção de uma alimentação saudável. Políticas públicas devem ser direcionadas a fim de controlar esse problema, já que a obesidade é um fator limitante para a longevidade.