No abstract

No abstract

No abstract

No abstract

Microwave Irradiation. -A variety of imines (37 examples in all) is prepared in high yields by a microwave-assisted procedure using NaHSO4·SiO2 as an efficient heterogeneous catalyst. -(GOPALAKRISHNAN*, M.; SURESHKUMAR, P.; KANAGARAJAN, V.; THANUSU, J.; GOVINDARAJU, R.; J.

No abstract

A novel class of 4,6-diaryl-4,5-dihydro-3-hydroxy-2[H]-indazoles 25-32 were synthesized and evaluated for their in vitro antibacterial and antifungal activities. Four Compounds, which all possessed electron withdrawing functional groups (ZCl, ZNO 2 , ZBr) 27, 28, 30 and 32 were more potent against the tested bacterial/fungal strains than the standard bacterial and fungal drugs ciprofloxacin and fluconazole respectively.

This synthesis of imines has been carried out efficiently by the condensation of carbonyl compounds with amines in the presence of silica gel supported sodium hydrogen sulfate (NaHSO4.SiO2) as a heterogeneous catalyst under microwave irradiation in solvent-free conditions. NaHSO4.SiO2 can be recovered and re-used up to ten times by simple washing with diethyl ether after each use and activated in an oven at 120 °C for 1 h, thus rendering the process more economical.