Carbohydrates U 0500 Synthesis and Biological Activities of New Hydroxy-3-pyrazolyl-4H-chromen--4-ones and TheirO-Glucosides. -The glucosides (VIII) show greater pharmacological significance than their aglycones (V). -(HATZADE, K. M.; TAILE, V. S.; GAIDHANE, P. K.; HALDAR, A. G. M.; INGLE*, V. N.; Indian J.

in Wiley InterScience (www.interscience.wiley.com).A series of 2-(4-hydroxyphenyl)-4,5-disubstituted imidazoles (1a-e) prepared from a-diketones, ammonium acetate, and p-hydroxybenzaldehyde, which were glucosylated by using a-acetobromoglucose to form 2-(4-O-b-D-2,3,4,6-tetra-O-acetyl-glucosidoxyphenyl)-4,5-disubstituted imidazoles (2a-e) which on catalytic deacetylation with CH 3 ONa in methanol afforded the title compound 2-(4-O-b-D-glucosidoxyphenyl)-4,5-disubstituted imidazoles (3a-e). Compounds were characterized by elemental analysis and by instrumental technique, similarly the title compounds were investigated for antimicrobial and antifungal activity.

The 7-hydroxy-3-formyl-4H-chromen-4-one 1 reacted with various cyclic 1,2-dicarbonyl compounds in the presence of ammonium acetate to furnish 7-hydroxy-3-([4,5-fused] imidazol-2-yl)-4H-chromen-4-ones 2a-f, which on glucosylation with a-acetobromoglucose affords 2,3,4,6-tetra-O-acetyl-b-D-glucopyranosyloxy-3-([4,5-fused] imidazol-2-yl)-4H-chromen-4-ones 3a -f. 7-O-b-D-Glucopyranosyloxy-3-([4,5-fused] imidazol-2-yl)-4H-chromen-4-ones 4a -f were prepared by deacetylation with anhydrous zinc acetate in absolute methanol. The structure of these new O-b-D-glucosides was established on the basis of chemical, elemental, and spectral analysis. These compounds were evaluated for their in vitro biological activity.

No abstract

No abstract

Carbohydrates U 0500Synthesis of Novel Galactopyranosyl-Derived Spiro Barbiturates. -Eleven title compounds of type (VI) are prepared and found to possess antibacterial and antifungal activities. -(INGLE*, V. N.; GAIDHANE, P. K.; DUTTA, S. S.; NAHA, P. P.; SENGUPTA, M. S.; J. Carbohydr. Chem. 25 (2006) 7-9, 661-671; Dep. Chem., Nagpur Univ., Nagpur 440 010, India; Eng.) -M. Bohle 21-167

Nanocrystalline α-Fe2O3 is synthesized by sol-gel technique. The prepared nanomaterial was characterized by X-ray diffraction (XRD), SEM, TEM, Fourier Transform Infrared (FTIR) spectroscopy, Vibrating Sample Magnetometry (VSM) and photoluminescence (PL) techniques. X-ray powder diffraction analysis confirmed the formation of α-Fe2O3. Electron microscopy showed spherical morphologies with an average particle size of 30-40 nm. The magnetic property of the prepared material was studied by VSM at room temperature. VSM study shows superparamagnetic nature of the synthesized nanoparticles. Photoluminescence (PL) emission spectra show intense broad emission band centered at 570 nm with 393 nm excitation indicating its usefulness for w-LED application. The CIE-chromaticity color coordinates of prepared material were calculated. The photocatalytic activity of the α-Fe2O3 nanoparticles was analyzed and the nanopowder exhibited good photocatalytic activity for the removal AO7 from its aqueous solution.

No abstract