Synthesis, characterization, biologically and antioxidant active of some 2-substitued 3,5-dimethyl-4-ethoxy carbonyl pyrrole derivatives

Ultrasound and Nano‐Catalysts: An Ideal and Sustainable Combination to Carry out Diverse Organic Transformations

“…Pyrroles are important class of bioactive heterocycles that possess anti‐oxidant, anti‐inflammatory, anti‐viral and anti‐tumor activities . Shahvelayati et al .…”

Clauson–Kaas pyrrole synthesis using diverse catalysts: a transition from conventional to greener approach

“…Among the diverse heterocyclic compounds, N-containing heterocycles are found in many natural products [ 1 – 3 ] and biologically active molecules [ 4 – 7 ]. Pyrroles are a significant class of five-membered aromatic nitrogen-containing heterocyclic skeletons that have attracted much attention due to their broad spectrum of biological activity, such as anticancer [ 8 – 10 ], antiviral [ 11 – 12 ], antibacterial [ 13 – 15 ], antimalarial [ 16 – 17 ], anti-inflammatory [ 18 – 19 ], anti-oxidant [ 20 – 22 ], antifungal [ 23 – 24 ] and antibiotic [ 25 – 26 ] and as enzyme inhibitors [ 27 – 28 ]. Several pharmaceuticals, polymers and naturally occurring compounds, including heme, chlorophyll, vitamin B12, porphyrins, chlorins, and bacteriochlorins also contain pyrroles rings ( Figure 1 ).…”

Synthesis and investigation of antioxidant and antimicrobial activity of new pyrazinopyrroloazepine derivatives using Fe3O4/CuO/ZnO@MWCNT MNCs as organometallic nanocatalyst by new MCRs

“…[14][15][16][17][18] Also, pyrrole and its derivatives are among the most important nitrogen-containing heterocyclic compounds that exist in the structure of many natural products including bile pigments, heme, cytochromes, vitamin B 12 , and alkaloids. [19,20] Pyrrole compounds are reported active as antibacterial, [21] antioxidant, [22] anti-inflammatory, [23] antitubercular, [24] and antitumor [25] drugs.…”