Research has been carried out on the use of the symbiotic “Rumimaster” in balanced diets of highly productive cows in the conditions of the breeding plant “Kirovskaya meadow-bog experimental station”. The experiment was carried out on two groups of animals in the middle of lactation with a duration of 90 days. The inclusion of the feed additive “Rumimaster” in the diet of experienced cows contributed to an increase in the gross production of natural and 4% fat milk by 124.5 kg and 128.4 kg, the yield of milk fat and milk protein by 5.2 and 4.1 kg, respectively. … The differences between the groups for these parameters were in the range of 5.1-5.7%. The productivity of cows for 305 days of lactation in the experimental group was higher than in the control by 7.5%. The symbiotic “Rumimaster” promoted the activation of digestion processes, which was reflected in the increase in the time of feed consumption and the duration of the chewing gum. The cows of the experimental group showed an increase in the level of digestibility of the main nutrients. In terms of the digestibility of crude protein and crude fiber, the experimental group of cows significantly exceeded the indicators of the control group by 3.3 and 3 absolute percent, respectively. The blood biochemical parameters of the animals of the experimental and control groups were within the physiological norm. The economic evaluation of the research results showed the effectiveness of the use of the symbiotic “Rumimaster” in the diets of lactating cows, which was expressed in the receipt of additional profit from one cow in the amount of 1,344.79 rubles for the period of experience and an increase in the profitability of milk production by 2.1 absolute percent.
Применение имплантов в коррекции диафрагмальной грыжи у новорожденныхThe use of implants for surgical treatment of congenital diaphragmatic hernia in newborns Врожденная диафрагмальная грыжа (ВДГ) -патология, которая требует обязательной хирургической коррек-ции. При значительных дефектах диафрагмы, например аплазии ее купола, зачастую возникает необходимость в использовании имплантационных материалов. До сих пор нет единой точки зрения по вопросу выбора имплан-та. В статье представлены результаты сравнительного анализа лечения новорожденных (n = 40) с левосторонней ложной ВДГ. Всем пациентам была выполнена торакоскопическая пластика купола дифрагмы. По типу использо-ванного имплантационного материала детей разделили на две группы: для первой (n = 16) применяли синтетичес-кие импланты «Экофлон» («НПК "Экофлон"», Россия), для второй (n = 24) -биологические импланты Permacol (Tissue Science Laboratories, Великобритания). Результаты исследования показали преимущества биологичес-кого импланта: время операции при его использовании было меньше (106 мин против 144 мин при использова-нии «Экофлона», p <0,05); число рецидивов -также меньше (28 % против 54 %, однако p >0,05); случаев от-торжения импланта не было (при использовании «Экофлона» у двух пациентов началось воспаление, p <0,05).Congenital diaphragmatic hernia (CDH) is an absolute indication for surgical treatment. In case of extensive defects of the diaphragm, such as diaphragmatic aplasia, the use of implants is required. So far, there is no unanimous opinion on the type of the implant. The article presents a comparative analysis of treatment of 40 newborns with left pseuso-CDH. All patients received thoracoscopic repair of the diaphragmatic cupula. The patients were divided into two groups according to the type of the implant: 16 newborns received Ecoflon synthetic implants (Ecoflon Scientific and Production Complex, Russia) and 24 newborns received Permacol biologic implants (Tissue Science Laboratories, UK). The study demonstrated the advantage of the biologic implant over the synthetic one: the surgery took less time (106 minutes compared to 144 minutes with Ecoflon, p <0.05); relapses were also more rare (28 % and 54 %, respectively; however, p was >0.05); no implant rejection was observed (with Ecoflon, two patients responded with inflammation, p <0.05).Ключевые слова: новорожденные, врожденная диафрагмальная грыжа, торакоскопия, имплант, имплантационный материал, «Экофлон», Permacol
Anorectoplasty and pull-through procedure can be performed with extended mobilization or tension anastomosis, which can compromise the vasculature of the rectum. We aimed to analyze the histopathological ndings, hypoxia biomarker values and to correlate the incidence of anal stenosis and defecation disorders of both conditions in experimental models. MethodsWe created anorectal reconstruction models during anorectal mobilization with extended mobilization with impaired vascularization (group I) and tension anastomosis (group II) in rats. Hypoxia biomarker values was assessed in both groups and in sham operated animals (group III). The histopathological changes on the 3 rd postoperative day, anal stenosis and defecation disorders on the 35 th day are compared with each other and with a control group (group IV). ResultsHypoxia biomarker levels con rmed postoperative ischemia in I -III groups compared to the control.Groups I, II are accompanied by pronounced histopathological changes in the anorectum on the 3rd postoperative day and accompanied by severe brosis on the 35 th day. In comparison to group III, both groups showed defecation disorders and anal stenoses. ConclusionExtensive mobilization with vascular impairment and tension anastomosis resulted in similar ischemia with histopathologic changes, which in the long term resulted in brotic changes associated with defecation disorders.
Purpose. Presentation of clinical cases of rare combination of omphalocele with pylorostenosis in the postoperative period and additional liver lobe. Materials and methods. In National Medical Research Center for Childrens Health of health surgical ward of newborns and infants for the 2019 us operated 2 children who performed surgery involving intra-operative decision making about further surgical tactics. Results. the results of surgical treatment of newborns with omphalocele combined with hypertrophic pylorostenosis and extra liver lobe are presented. Conclusions. In patients with malformations of the anterior abdominal wall in the postoperative period, when regurgitation syndrome appears, it is necessary to make a differential diagnosis between the functional and organic causes of obstruction. When confirming the organic nature of the obstruction, surgical intervention is indicated. It is necessary to be able to timely and objectively assess the risks and expediency of the approach when choosing surgical tactics in each individual case.
The results of long-term research on the use of drained lowland peat and developed soils in feed production in the North-East of the European part of Russia are presented. The main agroecological technologies for the production of high-quality feed in soil-protective crop rotations, long-term pastures on drained low-lying peat soils and methods for using developed peatlands in intensive haymaking mode are proposed.
BACKGROUND: Duodenal atresia is one of the most common malformations of the intestine in newborns. Both open surgical interventions and the laparoscopic method eliminate duodenal obstruction. AIM: This study conducts a comparative analysis of the results of treating newborns by these methods. MATERIALS AND METHODS: This paper summarizes the experience of treating 185 newborns operated in the clinic for duodenal obstruction. Two groups of patients are presented: the first included 110 children operated on laparoscopically, the second included 75 patients operated on by the open method. Both groups are comparable regarding newborn anthropometric data, age at the time of surgery, and the presence of concomitant anomalies. The study considered indicators characterizing the surgical intervention and the course of the postoperative period. RESULTS: In a series of studies, there were no differences between groups in interpreting the cause of obstruction (p = 0.184) and the presence of an incomplete turn (p = 0.134). Operating time in the laparoscopy group was higher than in the laparotomy group (75 min and 70 min, p 0.001). However, the reduced duration of mechanical ventilation, earlier initiation of feeding, transition to complete enteral nutrition and reduced length of hospital stay suggest the benefits of laparoscopy over laparotomy for treating congenital duodenal obstruction (p 0.001). The frequency of postoperative complications is not high in both groups (p = 0.634). The analysis results showed that laparoscopy does not complicate the intraoperative interpretation of organ relationships, provides a more favorable course during the postoperative period, and does not increase the number of postoperative complications. CONCLUSION: The laparoscopic method improves medical efficiency in treating newborns with duodenal obstruction than open surgery.
PurposeAnorectoplasty and pull-through procedure can be performed with extended mobilization or tension anastomosis, which can compromise the vasculature of the rectum. We aimed to analyze the histopathological findings, hypoxia biomarker values and to correlate the incidence of anal stenosis and defecation disorders of both conditions in experimental models. MethodsWe created anorectal reconstruction models during anorectal mobilization with extended mobilization with impaired vascularization (group I) and tension anastomosis (group II) in rats. Hypoxia biomarker values was assessed in both groups and in sham operated animals (group III). The histopathological changes on the 3rd postoperative day, anal stenosis and defecation disorders on the 35th day are compared with each other and with a control group (group IV). ResultsHypoxia biomarker levels confirmed postoperative ischemia in I – III groups compared to the control. Groups I, II are accompanied by pronounced histopathological changes in the anorectum on the 3rd postoperative day and accompanied by severe fibrosis on the 35th day. In comparison to group III, both groups showed defecation disorders and anal stenoses. ConclusionExtensive mobilization with vascular impairment and tension anastomosis resulted in similar ischemia with histopathologic changes, which in the long term resulted in fibrotic changes associated with defecation disorders.
Medical rehabilitation is an integral part of the treatment for surgical patients. Regarding pediatric patients with anorectal malformations, the success of the result of surgical treatment is mainly a correctly selected rehabilitation program, including methods of individual physiotherapy. Disturbances of intestinal transit, such as chronic constipation and anal incontinence, according to the world literature, occur in the study group in up to 30% of cases. According to the social significance of constipation and anal incontinence, the psychological aspects, the disabling component, children with anorectal malformations need early and long-term rehabilitation, adapted to their needs. At the moment, there are regulatory documents describing the principles of medical rehabilitation of children, its main characteristics, however, there are no protocols for the use of physiotherapy methods regarding the manifestations of colon transit disorders. Aim. Analysis of modern literature data on physiotherapeutic methods of rehabilitation of children with anorectal malformations. Material and methods. After determining the research criteria, a basic literature review using Web of Science, PubMed, electronic library was conducted, as a result 186 articles were selected that met the search criteria. After the initial assessment, 10 full-text articles were accepted for the analysis. Results. We have assessed the opportunity and mechanisms of the therapeutic action of sacral stimulation and tibial neuromodulation, the effect of various types of currents and a high-intensity magnetic field on the muscles of the complex, studied the possibility and results of using biofeedback therapy in children with colon transit disorders after operations on the anorectal body area in 421 children in 10 studies. Conclusion. Based on the results of scientific research, a range of physiotherapy methods have been established that are effective in relation to rehabilitation measures in children with anorectal malformations.
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