The data on histological studies of organs of suckling piglets that died from Aujeszky's disease presented in the article. To study of the microscopic changes, organ and tissue samples were taken from 5 suckling pigs (aged 4 to 6 days old). In all piglets, the diagnosis was confirmed by polymerase chain reaction. For histological studies, tissue samples were taken from the following organs: lungs, stomach, intestines, liver, pancreas, kidneys, thymus, lymph nodes, spleen, brain and spinal cord. The studies established that as a result of the Aujeszky’s disease virus impact on various organs and tissues, in dead pigs, significant pathomorphological changes are observed in most parenchymal organs. As a result of the histological studies of the internal organs of the pigs, died due to Aujeszky's disease the presence of significant microscopic changes in all morphological formations of these organs were found. It was described a number of micromorphological signs of piglets pathological changes and a set of criteria that can be used to substantiate a postmortem diagnosis of this disease was identified.
Aujeszky’s disease, also known as pseudorabies is an acute infectious viral disease in a variety of mammals caused by Suid herpesvirus 1, a member of the subfamily Alphaherpesvirinae and the family Herpesviridae. This virus causes significant economic losses in agriculture of numerous countries. In particular, in pig farming, the main losses are currently associated with restrictions of international trade, as well as the cost of vaccination or slaughter of infected animals. The main reservoirs species of this disease are considered to be wild boars and domestic pigs. So, in this article the authors performed a comparative retrospective analysis of the prevalence of Aujeszky’s disease among these species in Ukraine over 2009–2020 by systematizing and analyzing the epizootic data and results of serological studies. As a result of the conducted research, there is a clear trend that shows the reduction in the number of locations in Ukraine (farms, households, etc.) with domestic pigs affected by Aujeszky’s disease. Thus, in 2009 four such farms were found, and in 2018 – only one. During 2014–2016 and 2019–2020, affected farms and locations were not registered for this disease. In total, 21 such points with infected pigs were registered during the analyzed period. As for wild boars, during the analyzed 12 years, locations with animals affected by Aujeszky’s disease were registered only in 2013 and 2014 (two and one, respectively). It should be noted that all of those with infected wild boars were found in the AR Crimea. For the twelve years, the number of tested sera samples from domestic pigs amounted to 378,678 (7.4% were positive) and from wild boars – 9,052 (19.8% were positive). As a result of comparative geographical analysis of the obtained data on the detection of specific humoral antibodies to the Aujeszky’s disease virus among both species for 12 years in the regions of Ukraine, there is no established clear correlation between the spread of the disease among wild boars and domestic pigs. Thus, the highest seroprevalence rates among wild boars were observed in the northern and northeastern parts of Ukraine, and in domestic pigs, on the contrary, in the southern and central parts of this country. It should be noted, that since 2014 the number of serological tests among both species for carriers of Aujeszky’s disease has significantly decreased.
Державний науково-дослідний інститут з лабораторної діагностики та ветеринарно-санітарної експертизи ПАТОЛОГОГІСТОЛОГІЧНІ ЗМІНИ В ОРГАНАХ ШЛУНКОВО-КИШКОВОГО ТРАКТУ ПОРОСЯТ ПРИ ХВОРОБІ АУЄСКІ У статті наведені данні щодо гістологічних досліджень органів шлунково-кишкового тракту поросят-сисунів що загинули від хвороби Ауєскі. Для вивчення мікроскопічних змін, зразки тканин органів були відібрані від 5 поросят-сисунів (віком від 4 до 6 днів). В усіх поросят діагноз був підтверджений методом полімеразної ланцюгової реакції. Проведеними дослідженнями встановлено, що в наслідок дії вірусу хвороби Ауєскі на органи й тканини шлунково-кишкового тракту, у загиблих поросят, спостерігаються значні патоморфологічні зміни. Описаний цілий ряд мікроморфологічних ознак патологічних змін при хвороби Ауєскі поросят та виявлено набір критеріїв, котрі можуть бути використані для обґрунтування посмертного діагнозу на дане захворювання. Ключові слова: хвороба Ауєскі, Suid Herpesvirus 1, поросята, гістологічні зміни, шлунково-кишковий тракт. Вступ. Хвороба Ауєскі (псевдосказ)-це гостро перебігаюче у вигляді епізоотій і спорадичних випадків контагіозне вірусне захворювання сільськогосподарських (в основному свиней) і диких тварин, хутрових звірів і гризунів, що завдає значних економічних збитків країнам з розвиненим свинарством [1]. Викликає захворювання вірус Suid Herpesvirus 1 (сімейство Herpesviridae, підродина Alphaherpesvirinae, роду Varicellovirus) [2]. Економічні збитки при хворобі Ауєскі складаються з загибелі тварин, вимушеного забою, зниження приросту маси тварини, втрати племінних якостей, вибракування туш, абортів, витрат на ліквідацію, загальну і специфічну профілактику хвороби [3]. Летальні випадки хвороби спостерігаються переважно у поросят, у дорослих свиней хвороба супроводжується встановленням тривалого або
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