Turi (Sesbania grandiflora L) is native to Southeast Asia. This plant is used as a medicinal plant and also a vegetable. Turi (Sesbania grandiflora L) is a plant that is efficacious for the treatment of various diseases such as analgesic, antipyretic, diuretic and laxative. The purpose of this study was to identify the content of secondary metabolites in turi leaf extract extracted with ethanol, ethyl acetate and n-hexane as solvents. This research was conducted in two stages, namely extraction by maceration method using ethanol, ethyl acetate and n-hexane as solvents. And the identification stage of secondary metabolites consisting of identification of alkaloids, steroids, terpenoids, saponins and flavonoids. The results showed that the positive ethanol and ethyl acetate extracts contained flavonoids, saponins, terpenoids and steroids, while the negative n-hexane extract contained secondary metabolites.
Cayenne pepper (Capsicum frutescens L.) is a plant that has many benefits, one of which is as an anti-inflammatory. The anti-inflammatory effect of cayenne pepper was tested on white rats in the form of a gel. Two gel formulas were used with different concentrations of propylene glycol as additive, 25% and 30%, respectively. White rats were grouped into 4 groups, negative control group (gel base), positive control group (Voltaren® Emulgel), gel formula 1 group (enhancer 25%), and gel formula 2 (enhancer 30%). Albumen was induced on the backs of white rats then samples were given. Skinfold thickness measurements were taken every 1 hour for 6 hours. The data obtained in the form of skin thickness values (mm). The % Inflammation Inhibition (% PI) was calculated for each sample. Formula 1 and Formula 2 gave %PI of 32.58 ± 1.80 and 40.75 ± 5.71, respectively. Both formulas had an anti-inflammatory effect against edema on the back of rats although not better than Voltaren® Emulgel. Based on One Way ANOVA test, Formula 2 has a better anti-inflammatory effect than Formula 1. LSD test results show that %PI Formula 2 is similar to %PI Voltaren® Emulgel with a significance value of 0.117 (>0.05).
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