No abstract

Background: Systemic Lupus Erythematosus (SLE) is an autoimmune disease with wide range of clinical symptoms. The patients frequently complain musculoskeletal involvement during the active state of the disease. Musculoskeletal manifestation in SLE patients is an important sign in making early diagnosis and monitoring treatment response. This study aims to determine the presentation of musculoskeletal involvement of SLE patients in Dr. Hasan Sadikin General Hospital Bandung.Methods: a descriptive cross-sectional quantitative study done by interviewing SLE patients concerning musculoskeletal manifestation as the primary data and tracking their medical record as the secondary data. Study was conducted between September to November 2016 in Rheumatology Clinic Dr. Hasan Sadikin General Hospital Bandung.Result: Ninety-seven SLE patients, 91 females (93,81%) and 6 males (6,19%), were enrolled in this study with mean age 35.12 (±10.91) years. The three highest proportions of muskuloskeltal manifestations were arthritis of the knee (84,5%), myalgia of upper back(40,2%), and muscle weakness (15,5%). We did not find any Jaccoud’s Arthropathy (JA) and tendinitis manifestation. Osteoporosis were occured in 4 patients (4,12%), whereas gout arthritis, spondytlitis, osteoarthritis, rotator cuff syndrome, and rhupus wereonly occured in one patient (1,03%), respectively.Conclusion: The common musculoskeletal manifestation in SLE patients were arthritis of knee, myalgia of upper back, and muscle weakness. Only small portion of patients suffered from osteoporosis, gout arthritis, spondytlitis, osteoarthritis, rotator cuff syndrome, and rhupus.Keyword: musculoskeletal manifestation, musculoskletal involment, SLE

Background: Sudden death (SD) is a sudden and unexpected death with an unknown cause. However, it has been assummed that the most common causes of sudden deaths are cardiovascular or non-cardiovascular causes such as gastrointestinal disease, respiratory disease, genitourinary disease, epilepsy, and trauma. This study aimed to portray histopathological findings and causes of sudden cardiac death (SCD) cases based on 5 year autopsy experience in a tertiary hospital in Bandung, Indonesia. Methods: This study was a descriptive cross-sectional study exploring causes of SCD from 2015 to 2019 at Dr. Hasan Sadikin General Hospital, Bandung, Indonesia. All medical records with SCD and histopathology findings were retrieved from September to December 2020. Only cases with histopathological examination results were included.Results: SCD was found in 7 of 16 patients with sudden death. Coronary atherosclerosis was the most common (n=4), followed by myocardial infarction (n=2) and ruptured aortic aneurysm (n=1). Myocarditis and calcific aortic valve diseases were not found.Conclusions: In this study, the most common cause of SCD is coronary atherosclerosis, which is identified mainly in older and male patients.

Pengetahuan dasar topografi anatomi dari nervus fasialis sangat penting untuk pada aplikasi klinis. Ukuran nervus fasialis yang sangat kecil dan kurang nya penanda struktur saraf tersebut padadaerah wajah menjadikan cabang ekstra kranial dari nervus fasialis sulit untuk diidentifikasi. Untuk itu pentingnya kemampuan ketrampilan diseksi pada beberapa jaringan seperti jaringan yang segar dan jaringan yang sudah dilakukan preservasi. Tujuan penelitian ini adalah untuk membandingkan diseksi anatomi dari nervus fasialis preaparat dari jaringan yang segar dan dari jaringan yang sudah dilakukan preservasi. Metode yang digunakan untuk menentukan topografi ekstra kranial nervus fasialis dilakukan dengan diseksi anatomi pada daerah kepala dari 3 jenazah yang berasal dari Departemen Forensik dan 3 kadaver laboratorium. Garis insisi dimulai dari garis tengah melewati glabela,menuju puncak hidung dan sampai pada lekukan vertikal antara hidung dan mulut. Kemudian dengan menyusuri bagian-bagian kulit, lapisan demi lapisan akan dipisahkan untuk mengidentifikasi cabang dari nervus fasialis. Hasil penelitian ini menunjukkan  bahwa pada diseksi anatomi dengan menggunakan jaringan yang sudah dipreservasi, nervus fasialis dan cabang-cabangnya mudah untuk diidentifikasi, tetapi sulit untuk memisahkan lapisan-lapisan kulit daerah wajah dari lapisan Superfisial Musculo Aponeurotic System (SMAS).Kesimpulan penelitian menunjukkan bahwa identifikasi ekstra kanial nervus fasialis lebih mudah dilakukan pada jaringan yang sudah terpreservasi. Sedangkan untuk mengidentifikasi lapisan lapisan kulit pada bagian wajah lebih mudah dilakukan pada jaringan yang masih segar.