Introduction: Imprint cytology is an economical, simple and quick method with excellent cytological clarity but cannot provide information on the depth of invasion. Frozen section is the standard method of intraoperative diagnosis but is limited by its cost, need of qualified technical staff and the freezing arte facts. Thus, both the techniques have their own limitations and combining these techniques helps in achieving high diagnostic accuracy rates. Aims: 1. To assess the combined role of imprint cytology and frozen section in the diagnosis of tumours of various organs. 2. To compare the diagnostic accuracy of imprint cytology and frozen section individually with that of the histopathological diagnosis. Materials and Methods: The present study was done in the pathology department of Bangalore medical college and research institute for a period of one year. A total of 50 surgical specimens from various organs were studied using imprint cytology and frozen section. The results of both the techniques were compared with the gold standard histopathological diagnosis. Results: Out of 50 cases, majority were ovarian neoplasms comprising of 21 (42%) cases followed by thyroid (14%), breast (12%) and salivary gland (10%) neoplasms. The majority of the cases were malignant (50%) followed by beingn (40%), borderline (6%) and metastatic (4%). The overall diagnostic accuracy of imprint cytology and frozen section in various organs were 94% and 98%respectively. The combined diagnostic accuracy was 98%. Conclusion: Imprint cytology and frozen sections are interdependable intraoperative diagnostic modalities. Imprint cytology alone may not be able to provide a correct diagnosis. Thus, a combination of imprint cytology and frozen section helps in achieving high diagnostic accuracy rates and in distinguishing benign and malignant lesions.
Introduction:One of the biggest challenges faced by forensic pathologists is death due to electrocution. In almost half of all cases no gross pathological findings can be seen. The history surrounding the cause of death and circumstantial evidence is sometimes ambiguous and possesses great difficulty. Aim: To study the various histopathological changes in heart in electrocution. Methods and materials: In the present study, a total of 15 heart specimens in electrocution deaths and 15 normal heart specimens are considered during the study period of one year from 2015 to 2016. Case details are obtained from the records and analyzed. The histopathological findings are recorded in a proforma. Results: Myofibre break-up, separation of sarcomeres and extravasation of RBCs are found in all the 15 cases of electrocution (100%). The other findings are disarray of the myofibres (87%), hyper contracted myocyte with squaring of nuclei (73%), myocellular segmentation (33%) and myocyte vacuolization (20%). Conclusion: The histopathological changes in heart definitely provide an additional clue in the diagnosis of electrocution deaths. Most of the histopathological changes in heart are found consistently in electrocution cases compared to that of the normal hearts. Hence, their presence can be relied upon in the diagnosis of electrocution deaths and in reducing the number of negative autopsies.
BACKGROUND: Fibroids are benign smooth muscle neoplasms that may occur singly, but more often are multiple. Uterine tumors are the most common and the leading cause of hysterectomy in women. METHODS: The present study is a prospective study conducted in the department of pathology, Andhra Medical College, King George Hospital, Visakhapatnam in the period of one year, from March 2014 to March 2015. RESULTS: We received a total of 368 hysterectomy and 5 myomectomy specimens during this period, out of which, 249(66.7%) were single and 124(33.3%) were multiple. The age group ranged from 20 to 69. The most common location was intramural 243(65.1%) cases, subserosal were 51(13.7%), submucosal were 18(4.8%), cervical were 7(1.8%) and 2(0.5%) were broad ligament fibroids. The size ranged from as large as 19 cm to as small as seedling fibroids of size 0.1cm. Microscopically, the most common degeneration was hyaline degeneration 80 cases, 5 myxoid, 5 cystic and one case of chondroid degeneration. 6 cases showed calcifications. The most common age group was seen in the age group of 40-49 which were 207 cases (55.5%). 51(13.7%) cases were associated with adenomyosis. The results from our study were comparable with those reported in literature and provide a simple integrated pathogenetic view for further thinking, to establish new therapeutic options. CONCLUSIONS: The clinico-social and economic burden of uterine leiomyomas is increasing and requires future studies to clarify the etiopathogenesis and elaborate new and effective therapies for this condition.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.