Objective
To evaluate the outcomes of microneedling in patients with atrophic post-acne scars.
Methodology
A retrospective cross-sectional study was conducted at the Department of Dermatology, Patel Hospital for a duration of six months. Patients who were diagnosed with moderate to severe-grade atrophic acne scars were enrolled in the study. Patients with a history of photosensitivity, systemic lupus erythematosus, and xeroderma pigmentosum were excluded from the study. Goodman and Baron’s acne scar-grading system was used to evaluate the degree of atrophic scarring. A total of three sessions divided into four weekly intervals were conducted. The scar-grading was done before the procedure and after three treatment sessions using Goodman and Baron's acne scar grading system.
Results
A total of 50 patients were included in this study; 36 (72%) were females and 14 (28%) were males, with a mean age of 30.92±6.19 years. A decrease in the acne scar-grade was noted from grade III to grade II after three sessions of treatment. A significantly higher number of patients were in grade II after three-month sessions compared with before treatment (p=0.009), and a significantly lesser number of patients were in grade III (p=0.045). A significantly higher proportion of patients with moderate acne scars, as compared to severe, were in grade II (77.3% vs. 22.7%; p<0.001).
Conclusion
In this study, we found an improvement in the scar grade after microneedling sessions. However, as the study was retrospective, we suggest prospective randomized controlled trials in our set-up to better uncover the role of microneedling in reducing acne scars.
Introduction: Lichen amyloidosus (LA) is the major variant of the primarycutaneous amyloidoses which present with severe and therapy resistant itching. Varioustherapeutic modalities such as antihistamines, intralesional injection or topical applicationof corticosteroids, etretinate, UVB irradiation and dermoabrasion have been employed withvariable success. Some authors have observed encouraging beneficial clinical effects by usingtopical dimethyl sulphoxide (DMSO). Objectives: The objective of the study was to: evaluatethe efficacy of topical Dimethyl sulfoxide (D.M.S.O) 70% in Lichen Amyloidosis. Study Design:Case series. Settings: This study was conducted at dermatology department, Abbasi ShaheedHospital in outpatient department (OPD). Duration of Study: The data collection was done in06 months after approval of synopsis. From: 2nd June 2013 to 2nd December 2013. Results: Inthis study, out of 71 cases, 42.25%(n=30) were between 16-40 years while 57.75%(n=41) werebetween 41-80 years of age, mean+sd was calculated as 41.79+10.87 years, 26.76%(n=19)were male and 73.24%(n=52) were females, 36.62%(n=26) had <6 months and 63.38%(n=45)had ≥6 months of duration, frequency of efficacy of topical dimethyl sulfoxide (D.M.S.O) in lichenamyloidosis reveals 66.20%(n=47) while 33.80%(n=24) did not show efficacy. Conclusion: Weconcluded that the efficacy of topical Dimethyl sulfoxide (D.M.S.O) 70% in Lichen Amyloidosisis higher and in accordancde with other studies. It may be utilized in future for such cases.
Objective: The main purpose of the study is to compare the outcomes of Limberg flap and open procedure to treat the chronic pilonidal sinus. Pilonidal sinus is a disorder of the sacrococcygeal region mostly found in younger folk. Its treatment consists of several methods but in this study, we will go through Limberg flap and open procedure to compare the outcomes of both methods. Study design: Comparative study. Material & Methods: This study was conducted from January 2020 to December 2022. 84 patients included 59 males and 25 females having age between 18 to 40 years were part of the study. All the selected patients were diagnosed with chronic pilonidal sinus and recommended for surgery at sugery Unit1 sir ganga ram hospital Lahore, Pakistan. A total of 84 patients were divided into two groups, group1 consists of 42 patients treated for the Limberg flap technique. Group 2 also contains 42 patients treated for an open procedure. The patients who were suffering from the chronic pilonidal sinus were part of the study while patients who had acute inflammation of the sinus, history of previous treatment of pilonidal sinus were omitted from the study. Results: Out of 84 patients 42 were part of group 1 and the remaining 42 were in group 2. In group1, the mean ±SD age of patients was 26 ± 2.00, 30 (71.4%) males and 12 (28.5%) females. While in group2 the mean ±SD age was 25 ± 3.00, 29 (69%) were males and 13 (30.9%) females were part of this group. The measured p-value for both groups was <0.05. General characteristics of patients show that high percentage of males was affected from pilonidal sinus disease. In group1 patients who had a 2 days stay at the hospital, recurrence was reported in 10 (23.8%) patients with P-value >0.05, irregular scar formation was observed in 16 (38%) patients, the pain was reported in 18 (42.8%) patients, and wound healing after 2 weeks was noted in 20 (47%) patients. In group 2, patients had 6 days stay at the hospital, recurrence was reported in 13 (30.9%) patients with value >0.05, irregular scar formation was observed in 26 (61%) patients, the pain was reported in 34 (80%) patients and wound healing after 2 weeks was noted in 12 (28.57%) patients. p-value was measured <0.05 for all the parameters. Conclusion: Eventually, we concluded significant results of the Limberg flap than the open procedure. A high percentage of complications were measured in patients treated with the open procedure in comparison to the Limberg flap. Keywords: Chronic pilonidal sinus, Limberg flap, open procedure.
At the provincial level, the Khyber Pakhtunkhwa province reflects a high rate of unemployment (7.3 percent) than other provinces (Punjab 5.7 percent, Sindh 5 percent and Baluchistan 4 percent). At the provincial level too, there is a sharp decline in the employment share
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.