Objective
To evaluate the outcomes of microneedling in patients with atrophic post-acne scars.
Methodology
A retrospective cross-sectional study was conducted at the Department of Dermatology, Patel Hospital for a duration of six months. Patients who were diagnosed with moderate to severe-grade atrophic acne scars were enrolled in the study. Patients with a history of photosensitivity, systemic lupus erythematosus, and xeroderma pigmentosum were excluded from the study. Goodman and Baron’s acne scar-grading system was used to evaluate the degree of atrophic scarring. A total of three sessions divided into four weekly intervals were conducted. The scar-grading was done before the procedure and after three treatment sessions using Goodman and Baron's acne scar grading system.
Results
A total of 50 patients were included in this study; 36 (72%) were females and 14 (28%) were males, with a mean age of 30.92±6.19 years. A decrease in the acne scar-grade was noted from grade III to grade II after three sessions of treatment. A significantly higher number of patients were in grade II after three-month sessions compared with before treatment (p=0.009), and a significantly lesser number of patients were in grade III (p=0.045). A significantly higher proportion of patients with moderate acne scars, as compared to severe, were in grade II (77.3% vs. 22.7%; p<0.001).
Conclusion
In this study, we found an improvement in the scar grade after microneedling sessions. However, as the study was retrospective, we suggest prospective randomized controlled trials in our set-up to better uncover the role of microneedling in reducing acne scars.
Introduction: Lichen amyloidosus (LA) is the major variant of the primarycutaneous amyloidoses which present with severe and therapy resistant itching. Varioustherapeutic modalities such as antihistamines, intralesional injection or topical applicationof corticosteroids, etretinate, UVB irradiation and dermoabrasion have been employed withvariable success. Some authors have observed encouraging beneficial clinical effects by usingtopical dimethyl sulphoxide (DMSO). Objectives: The objective of the study was to: evaluatethe efficacy of topical Dimethyl sulfoxide (D.M.S.O) 70% in Lichen Amyloidosis. Study Design:Case series. Settings: This study was conducted at dermatology department, Abbasi ShaheedHospital in outpatient department (OPD). Duration of Study: The data collection was done in06 months after approval of synopsis. From: 2nd June 2013 to 2nd December 2013. Results: Inthis study, out of 71 cases, 42.25%(n=30) were between 16-40 years while 57.75%(n=41) werebetween 41-80 years of age, mean+sd was calculated as 41.79+10.87 years, 26.76%(n=19)were male and 73.24%(n=52) were females, 36.62%(n=26) had <6 months and 63.38%(n=45)had ≥6 months of duration, frequency of efficacy of topical dimethyl sulfoxide (D.M.S.O) in lichenamyloidosis reveals 66.20%(n=47) while 33.80%(n=24) did not show efficacy. Conclusion: Weconcluded that the efficacy of topical Dimethyl sulfoxide (D.M.S.O) 70% in Lichen Amyloidosisis higher and in accordancde with other studies. It may be utilized in future for such cases.
At the provincial level, the Khyber Pakhtunkhwa province reflects a high rate of unemployment (7.3 percent) than other provinces (Punjab 5.7 percent, Sindh 5 percent and Baluchistan 4 percent). At the provincial level too, there is a sharp decline in the employment share
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