BackgroundZika is a new disease in the American continent and its surveillance is of utmost importance, especially because of its ability to cause neurological manifestations as Guillain-Barré syndrome and serious congenital malformations through vertical transmission. The detection of suspected cases by the surveillance system depends on the case definition adopted. As the laboratory diagnosis of Zika infection still relies on the use of expensive and complex molecular techniques with low sensitivity due to a narrow window of detection, most suspected cases are not confirmed by laboratory tests, mainly reserved for pregnant women and newborns. In this context, an accurate definition of a suspected Zika case is crucial in order for the surveillance system to gauge the magnitude of an epidemic.MethodologyWe evaluated the accuracy of various Zika case definitions in a scenario where Dengue and Chikungunya viruses co-circulate. Signs and symptoms that best discriminated PCR confirmed Zika from other laboratory confirmed febrile or exanthematic diseases were identified to propose and test predictive models for Zika infection based on these clinical features.Results and discussionOur derived score prediction model had the best performance because it demonstrated the highest sensitivity and specificity, 86·6% and 78·3%, respectively. This Zika case definition also had the highest values for auROC (0·903) and R2 (0·417), and the lowest Brier score 0·096.ConclusionsIn areas where multiple arboviruses circulate, the presence of rash with pruritus or conjunctival hyperemia, without any other general clinical manifestations such as fever, petechia or anorexia is the best Zika case definition.
IntroductionSarcopenia is a condition diagnosed when the patient presents low muscle mass, plus low muscle strength or low physical performance. Muscle weakness in the oldest (dynapenia) is a major public health concern because it predicts future all-cause mortality and is associated with falls, disability, cardiovascular mortality and morbidity. Grip strength is a simple method for assessment of muscle function in clinical practice.ObjectiveTo estimate the grip strength and identify factors associated with handgrip strength variation in elderly people with low socioeconomic status.MethodsCross-sectional study based on a multidimensional assessment of primary care users that were 60 years or older. The sample size was calculated using an estimated prevalence of depression in older adults of 20%. A kappa coefficient of 0.6 with a 95% confidence interval was used to generate a conservative sample size of 180 individuals. Procedures: tests and scales to assess humor, cognition (MMSE), basic (ADL) and instrumental activities (IADL) of daily living, mobility (Timed Up and Go), strength, height, Body Mass Index (BMI) and social support were applied. Questions about falls, chronic diseases and self-rated health (SRH) were also included. Statistical Analysis: Mean, standard deviation and statistical tests were used to compare grip strength means by demographic and health factors. A multivariate linear model was used to explain the relationship of the predictors with grip strength.ResultsThe group was composed predominantly by women (73%) with a very low level of education (mean 3 years of schooling), mean age of 73.09 (± 7.05) years old, good mobility and without IADL impairment. Mean grip strength of male and female were 31.86Kg (SD 5.55) and 21.69Kg (SD 4.48) [p- 0.0001], respectively. Low grip strength was present in 27.7% of women and 39.6% of men. As expected, men and younger participants had higher grip strength than women and older individuals. In the adjusted model, age (p- 0.03), female sex (p- 0.0001), mobility (p- 0.05), height (p- 0.03) and depression (p- 0.03) were independently associated with low grip strength. For every second more in the mobility test, there was a mean decrease of 0.08 Kg in the grip strength. Elders with depression had a mean reduction of 1.74Kg in the grip strength in relation to those in the comparison groups. There was an average reduction of 8.36Kg in the grip strength of elderly females relative to males. For each year of age after 60 years, it was expected an average reduction of 0.11 Kg in the grip strength.Conclusionour results suggest that low grip strength is associated with age, female sex, height, depression and mobility problems in poor elderly. Grip strength can be a simple, quick and inexpensive means of stratifying elders’ risk of sarcopenia in the primary care setting. Efforts should be made to recognize weaker persons and the conditions associated to low grip strength in order to target early interventions to prevent frailty and disability.
This cross-sectional study was carried out in Manguinhos, Rio de Janeiro, Brazil and aimed to identify the prevalence and factors associated with familial violence perpetrated by caregivers against elderly dependents. A sample of 135 pairs was evaluated using instruments to assess both caregivers (social support, alcoholism, burden, violence) and elders (depression, cognition, functional capacity). Statistical tests compared the percentages of reported violence according to the characteristics of caregiver and elders. A logistic regression model investigated the association between violence and caregiver/ elder characteristics. More than 30% of caregivers gave responses consistent with risk of elder abuse. Among them, high burden level and comorbid alcohol abuse increased the risk of violence by 11 and 3.8 times, respectively. Elderly men were 2.9 times more likely to be mistreated than elderly women, and depressed ones were 6.9 times more likely to report mistreatment than those without depression. Conclusion: We detected a high prevalence of caregiver violence against elderly dependents, with substantially greater risk among caregivers with high levels of burden, alcohol-related problems, and those caring for depressed elders. Family support strategies are needed to reduce domestic violence and protect elderly victims.
Resumo: O envelhecimento populacional ocasionou aumento da dependência e da sobrecarga de cuidadores familiares de idosos dependentes. O objetivo foi verificar, entre cuidadores familiares, a prevalência de sobrecarga e os fatores associados a ela em uma região pobre e violenta do Rio de Janeiro, Brasil. Trata-se de estudo transversal com 140 idosos e cuidadores familiares, para investigar apoio social, maus tratos, coabitação e sobrecarga nos cuidadores familiares, além de dependência, declínio cognitivo e depressão no idoso. Modelos logísticos múltiplos foram construídos no intuito de explicar a sobrecarga dos cuidadores familiares. As seguintes características dos idosos se associaram à sobrecarga: idade (OR = 0,94; p < 0,002), depressão (OR = 2,59; p < 0,005) e declínio cognitivo (OR = 3,19; p < 0,03). Em relação aos fatores dos cuidadores familiares, apenas apoio social manteve a relevância (OR = 2,35; p < 0,005). Conclui-se que investigar e tratar depressão e demência em idosos, assim como prover apoio aos seus cuidadores, podem contribuir para o manejo efetivo da sobrecarga de cuidadores familiares, melhorando a qualidade do cuidado e a saúde de ambos.
BackgroundDengue epidemics have occurred in the city of Rio de Janeiro (Brazil) since 1986. In the year 2015, Zika and chikungunya viruses were introduced in the city, causing sequential and simultaneous epidemics. Poor socioeconomic conditions have been suggested as contributing factors of arboviral infection.ObjectiveTo describe the spatial distribution of human cases of symptomatic arboviral infections and to identify risk factors for infection in a poor community of Rio de Janeiro in the years 2015 and 2016.MethodsWe built thematic maps of incidence rates for 78 micro-areas in the Manguinhos neighborhood. The micro-areas congregate about 600 inhabitants. Simple and multiple multilevel logistic regression models were used to evaluate the association between the incidence of arboviral diseases and socio-demographic factors at both the individual and micro-area levels.ResultsFrom 2015 to 2016, 370 human cases of arbovirus infection were reported in the Manguinhos community: 123 in 2015 and 247 in 2016. There was a significant difference in the risk of arbovirus diseases among different micro-areas, but this was not explained by water and sanitation indicators. The cumulative incidence rate was 849/100,000 in two years. The incidence was greater in those individuals with familiar vulnerability (1,156/100,000 vs. 794/100,000). The multilevel adjusted model showed that the odds of acquiring an arbovirus infection was 55% greater in those with familiar vulnerability.ConclusionArbovirus infections cause a high burden of disease in Brazilian urban centers. Our results suggest that even in poor neighborhoods, there is a high spatial variability in the risk of acquiring an arbovirus infection. The conditions that favor vector proliferation and infection by arboviruses are complex and involve both individual and environmental characteristics that vary from place to place. To reduce the burden of arboviral diseases, continued public health policies and basic services should be provided to the communities at risk that consider specific local needs.
RESUMO O estudo se propôs a analisar as trajetórias na assistência das mulheres residentes no Município do Rio de Janeiro diagnosticadas com câncer de colo uterino que foram encaminhadas para tratamento em unidade de referência na atenção oncológica. Na primeira etapa do estudo, avaliou-se o prazo entre a confirmação do diagnóstico e o início do tratamento das mulheres matriculadas no ano de 2014, tomando como referência o prazo de até 60 dias fixado pela Lei Federal nº 12.372/2012 para início de tratamento do câncer no âmbito do Sistema Único de Saúde (SUS). Na segunda etapa, analisaram-se as narrativas de cinco mulheres sobre os caminhos percorridos na assistência desde a descoberta do diagnóstico até a primeira intervenção terapêutica, a partir de aspectos do cuidado integral em saúde. Observou-se que 88% dos tratamentos se iniciaram após o prazo de 60 dias e que 65,5% das mulheres foram diagnosticadas com doença avançada. A média para início de tratamento foi de 115,4 dias. Os principais problemas apreendidos na análise das trajetórias foram os relacionados à disponibilidade dos serviços e à integração das ações nos diversos níveis de atenção, bem como a falta de informação sobre a doença e o objetivo da realização do exame preventivo.
BackgroundIn Brazil, the incidence of dengue greatly increased in the last two decades and there are several factors impeding the control of the disease. The present study focused on describing the space-time evolution of dengue in Brazil from 2001 to 2012 and analyzing the relationship of the reported cases with socio-demographic and environmental factors.MethodsThe analytic units used in the preparation of thematic maps were municipalities. Statistical tests and multilevel regression models were used to evaluate the association between dengue incidence and the following factors: climate, diagnostic period, demographic density, percentage of people living in rural areas, Gross Domestic Product, Gini index, percentage of garbage collection and the rate of households with a sewage network.ResultsThe largest accumulation of dengue cases in Brazil was concentrated on the Atlantic coast and in the interior part of São Paulo State. The risk of dengue in subtropical and tropical climates was 1.20–11 times lower than that observed in semi-arid climates. In 2009–2010 and 2011–2012, the risks were ten and six times higher than in 2003–2004, respectively.ConclusionDengue is a common infection in the Brazilian population, with the largest accumulation of dengue cases concentrated on the Atlantic coast and in the interior area of São Paulo State. The high dengue rates observed in the Brazilian coastal region suggest that the cases imported from neighboring countries contribute to the spread of the disease in the country. Our results suggest that several socio-demographic and environmental factors resulted in the increase of dengue in the country over time. This is likely applicable to the occurrence of other arboviruses like Zika and chikungunya. To reverse the situation, Brazil must implement effective public policies that offer basic services such as garbage collection and sanitation networks as well as reduce vector populations.
Summary Objective: To evaluate the frequency of teenage pregnancy in Brazil, from 2000 to 2011, in all five Brazilian macroregions and age groups (10-14 and 15-19 years), correlating it with the human development index (HDI). Method: Descriptive epidemiological study, with cross-sectional design, performed by searching the database of the National Health System (Datasus), using information from the Information System (Sinasc). Results: There was a decrease in the percentage of live births (LB) from teenage mothers (10-19 years) in Brazil (23.5 % in 2000 to 19.2 % in 2011). This reduction was observed in all Brazilian macroregions in the group of mothers aged 15 to 19 years. The number of LB increased by 5.0% among mothers aged 10-14 years (increase in the North and Northeast and decline in the other macroregions). The proportion of LB shows an inversely proportional trend to HDI score, with the Southeast having the highest HDI and the lowest proportion of LB to teenage mothers in the country. Conclusion: Brazil shows a decline in the percentage of LB to adolescent mothers, tending to be inversely related to HDI score. It is important to empower strategies to address the problem, so that teenage pregnancy is seen as a personal decision rather than the result of a lack of policies targeting adolescent health.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
334 Leonard St
Brooklyn, NY 11211
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.