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Background: Coronavirus disease 2019 (COVID-19) pandemic management depends on public acceptance of vaccines and vaccine-induced herd immunity remains the best hope for putting a stop to the pandemic. However, vaccination reluctance for COVID-19 remains a significant issue. Aim: This study aimed to explore the correlation between COVID-19 phobia, intolerance of uncertainty, conspiracy mentality and vaccine hesitancy among Assiut University students. Subjects and method: Design: A correlational descriptive research design was used. Setting: this study conducted in six randomly selected faculties at Assiut University. Subjects: A convenient sample of 1300 male and female students from the selected faculties. Tools: Socio-demographic data, COVID-19 phobia scale, conspiracy mentality questionnaire, intolerance of uncertainty scale and vaccine conspiracy beliefs scale. The results: The participant"s students' mean age was 20.52 ±1.33 years. 80.9% had previously suffered from COVID-19. 73.1% of the students had first degree relatives with COVID-19.The total mean scores of the students regarding COVID-19 Phobia and intolerance of uncertainty scales were (50.30 ±13.31 and 28.67 ± 9.35) respectively, whereas the mean scores of the conspiracy mentality and vaccine conspiracy beliefs among the students were (29.70. ± 13.12 and 25.98 ± 9.48) respectively. Conclusion: The current study revealed a strong correlation between COVID-19, intolerance of uncertainty, vaccine conspiracy and conspiracy mentality among studied students and moderate relation between COVID-19, intolerance of uncertainty, vaccine conspiracy and conspiracy mentality and socio-demographic data. Recommendations: Use a different way of social media to explain the importance of vaccines e.g. posters, brochures, gestures, educational videos and innovative technologies such as interactive mobile apps.

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Objective: The aim of this study is to evaluate the effect of rehabilitation program on quality of life& coping Strategies among patients with knee osteoarthritis at Assiut University Hospital. Method: A quasi-experimental design study was used. Aconvenient sample included 50 patients with knee osteoarthritis 30 of them study group and were control group, who presented to the orthopedics outpatient clinic during 6 months. This study was performed at Assiut University Hospital. Tools of data collection included sociodemographic characteristics questionnaire, Coping strategies scale, quality of life scale for chronic disease . Result: The majority of studied and control groups were females with age group 45-65 years old. 62% of the studied group were illiterate , 70% of studied group and 60% of control group were complaining of this disease for more than 5 years. 22% of studied group had hypertension. More than half of the studied and control group were obese. There was statistically significant correlation between quality of life and affective orientation coping strategies among studied and control group before program. After program, there was statistically significant correlation between quality of life and affective orientation coping strategies. Conclusion: There was no statistically significant difference between studied and control group before program in relation to quality of life. However, there was statistically significant correlation between quality of life and affective orientation coping strategies among studied and control group. Recommendations: Nurses and other healthcare professionals can provide the treatment and prevention and make major contributions to the quality of life of people with knee osteoarthritis