Abstract. In the presented article, based on the detailed analysis of scientific sources and many years of own experience in production of the probiotic foods, the definition of "probiotics" in cosmetics, as well as the definition of "living" and "probiotic" cosmetics is proposed.The skin is a complex barrier organ that has a symbiotic relationship between microbial communities and host tissue via complex signals provided by the innate and the adaptive immune systems. It is constantly exposed to various endogenous and exogenous factors -physical, chemical, bacterial and fungal, as well as the effects of the hormonal disorders, which affect this balanced system potentially leading to inflammatory skin conditions comprising infections, allergies or autoimmune diseases. In opposition to the gut and stool microbiome, which has been studied and described for many years, investigations on the skin or scalp microbiome lasts only for last 10 years. Therefore, the screening of effective means of correcting and/or maintaining the human normoflora for the preservation of healthy skin microbiome today is an urgent task.It is well known that probiotics and prebiotics are helpful for specific disorders in the human body. Skeptics wonder: can the probiotics and prebiotics be scientifically applied in cosmetics? Different clinical studies indicated that they have special effects in cutaneous apparatus directly or indirectly, which can be considered from different aspects. Probiotic bacteriotherapy can have great potential in accelerating wound healing, in preventing and treating the skin diseases including eczema, atopic dermatitis, acne, allergic inflammation or skin hypersensitivity, UV-induced skin damage and cosmetics products. Therefore, some firms are already incorporating bacteria and/or their lysates into skin creams with the promise of «rebalancing» the community of bacteria that live in the human body and delivering healthier, more radiant-looking skin. However, such parameters as the type of probiotic, the form in which it is added to the formulation (living bacteria, lysates, etc.) and the recommended concentrations of these ingredients in cosmetic products that are safe and effective are still not defined. Due to currently widespread use of probiotic cosmetic products in the world beauty industry, the concept of "probiotic" in the cosmetic industry requires a clear definition.Key words: skin, microbiome, probiotic, «living cosmetics», «probiotic cosmetics», bifidobacteria, lactobacteria. «ЖИВА» ТА «ПРОБІОТИЧНА» КОСМЕТИКА: СУЧАСНИЙ ПОГЛЯД ТА ДЕФІНІЦІЇН. А. Ткаченко, доктор технічних наук, професор, завідувач кафедри, E-mail: nataliya.n2013@gmail.com О.П. Чагаровський, доктор технічних наук, професор, професор кафедри, E-mail: uaach@chr-hansen.com Н.О. Дец, кандидат технічних наук, доцент, доцент кафедри, E-mail: dets.nadin@gmail.com О.В. Севастьянова, кандидат хімічних наук, доцент, доцент кафедри, E-mail: elena.vladimirovn.sevastyanova@gmail.com Л.О. Ланженко, кандидат технічних наук, асистент кафедри, E-mail: lanj...
The expediency of optimization of starter cultures composition of mixed cultures Lactococcus sp. and mixed cultures Bifidobacterium bifidum BB 01 + Bifidobacterium longum BL 01 + Bifidobacterium breve BR 01 for the manufacture of fermented milk products and cosmetics for teenagers and people under the age of 40-45 years with probiotics has been substantiated.The value of titratable acidity, number of viable cells of bifidobacteria has been determined, as well as the most probable number of lactobacterium in fermented probiotic clots obtained with different ratios of mixed cultures Lactococcus sp. and mixed cultures of Bifidobacterium sp. in starter cultures compositions (the initial concentration of the mixed cultures (MC) Lactococcus sp. and MC Bifidobacterium sp. varied within the range of 1×105 – 1×106 CFU/cm3 of the inoculated milk, enriched with fructose as a growth factor of bifidobacteria). The high content of probiotics and the lowest values of titratable acidity are typical of the fermented milk clots obtained using starter cultures composition with a ratio of MC Lactococcus sp. : MC Bifidobacterium sp. 1 : 10. The maximum number of lactococci viable cells is observed in clots obtained using starter cultures composition with the initial ratio of MC Lactococcus sp. : MC Bifidobacterium sp. 10 : 1. The optimum ratio of MC Lactococcus sp. and MC Bifidobacterium sp. – 1 : 10 has been established (initial concentration of the cultures at inoculation – 1×105 and 1×106 CFU/cm3, respectively) for the production of fermented milk products and cosmetics with probiotics, where the maximum value of the quality aggregated factor – 7, 12 is noted.It is shown that a fermented probiotic milk clots obtained using starter cultures composition with an optimum ratio of cultures of lacto- and bifidobacteria (1 : 10) have good sensory characteristics, contain a high number of viable cells of bifidobacteria and lactobacteria – (9,15±0,14)×109 and (8,50±0,50)×108 CFU/cm3, respectively, and a low level of titratable acidity at a specified value of the active acidity and are safe in terms of microbiological characteristics
12. Novye kataliticheskie kompozitsii dlia selektivnogo okisleniia uglevodorodov na osnove soedinenii metalov peremennoi valentnosti i katalizatorov mezhfaznogo perenosa [Text] // Tezisy dokladov 7-go Neftehimicheskogo simpoziuma.-Kyiv, 1990.-230 p. 13. Reutskyy, V. V. Kataliticheskoe okislenie tsiklogeksana v akusticheskom pole [Text]: PhD thesis / V. V. Reutskyy.-Lviv, 1988.-119 p. усовершенсТвование Процесса окисления циклогексана Рассмотрен способ усовершенствования процесса жидкофазного окисления циклогексана. Определен положительный эффект кислородосодержащей добавки-Бис-2 цианетилового этера-на основные технико-экономические показатели процесса-конверсию сырья, селективность по продуктах окисления и соотношение целевых продуктов. Исследовано оптимальное соотношение компонентов бинарной каталитической системы. Предложен комплексный метод использования продуктов окисления циклогексана путем утилизации полученных побочных кислот эстерификацией их со спиртами. ключевые слова: окисление циклогексана, кислородосодержащая добавка, бинарная каталитическая система, конверсия сырья.
The article substantiates the prescription composition of combined ice cream using vegetable oils and basil extract. There were carried out research of the process of extraction of biologically active substances from dry basil leaves and mathematical modeling for a balanced fatty acid composition of the finished target product. The quality indicators of vegetable oils and milk basil extract are determined. There were obtained satisfactory results of the use of milk extract, sunflower and sesame oils as raw materials for the production of ice cream.
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