“Lving” and “probiotic” cosmetics: modern view and defenitions

Abstract

Abstract. In the presented article, based on the detailed analysis of scientific sources and many years of own experience in production of the probiotic foods, the definition of "probiotics" in cosmetics, as well as the definition of "living" and "probiotic" cosmetics is proposed.The skin is a complex barrier organ that has a symbiotic relationship between microbial communities and host tissue via complex signals provided by the innate and the adaptive immune systems. It is constantly exposed to various endogenous and exogenous factors -physical, chemical, bacterial and fungal, as well as the effects of the hormonal disorders, which affect this balanced system potentially leading to inflammatory skin conditions comprising infections, allergies or autoimmune diseases. In opposition to the gut and stool microbiome, which has been studied and described for many years, investigations on the skin or scalp microbiome lasts only for last 10 years. Therefore, the screening of effective means of correcting and/or maintaining the human normoflora for the preservation of healthy skin microbiome today is an urgent task.It is well known that probiotics and prebiotics are helpful for specific disorders in the human body. Skeptics wonder: can the probiotics and prebiotics be scientifically applied in cosmetics? Different clinical studies indicated that they have special effects in cutaneous apparatus directly or indirectly, which can be considered from different aspects. Probiotic bacteriotherapy can have great potential in accelerating wound healing, in preventing and treating the skin diseases including eczema, atopic dermatitis, acne, allergic inflammation or skin hypersensitivity, UV-induced skin damage and cosmetics products. Therefore, some firms are already incorporating bacteria and/or their lysates into skin creams with the promise of «rebalancing» the community of bacteria that live in the human body and delivering healthier, more radiant-looking skin. However, such parameters as the type of probiotic, the form in which it is added to the formulation (living bacteria, lysates, etc.) and the recommended concentrations of these ingredients in cosmetic products that are safe and effective are still not defined. Due to currently widespread use of probiotic cosmetic products in the world beauty industry, the concept of "probiotic" in the cosmetic industry requires a clear definition.Key words: skin, microbiome, probiotic, «living cosmetics», «probiotic cosmetics», bifidobacteria, lactobacteria. «ЖИВА» ТА «ПРОБІОТИЧНА» КОСМЕТИКА: СУЧАСНИЙ ПОГЛЯД ТА ДЕФІНІЦІЇН. А. Ткаченко, доктор технічних наук, професор, завідувач кафедри, E-mail: nataliya.n2013@gmail.com О.П. Чагаровський, доктор технічних наук, професор, професор кафедри, E-mail: uaach@chr-hansen.com Н.О. Дец, кандидат технічних наук, доцент, доцент кафедри, E-mail: dets.nadin@gmail.com О.В. Севастьянова, кандидат хімічних наук, доцент, доцент кафедри, E-mail: elena.vladimirovn.sevastyanova@gmail.com Л.О. Ланженко, кандидат технічних наук, асистент кафедри, E-mail: lanj...

Substantiation of the composition of a semi-solid dosage form with a probiotic component for use in dermatology

“…Features of the microbiome of dry skin can be the basis for studying the pathogenesis of psoriasis, and areas with high humidity -to study the pathogenesis of atopic dermatitis [2]. Numerous studies show the need to maintain the skin microbiome [2,3]. Moreover, the violation of the skin microbiome can be a consequence of infectious and inflammatory dermatoses and their treatment with antimicrobials, and the cause, as the reduction of the microbiome of this ecosystem normally leads to the activation of opportunistic pathogens and, consequently, to infectious disease.…”

“…The skin is constantly exposed to various endogenous and exogenous factorsphysical, chemical, bacterial and fungal, which affect this balanced system, potentially leading to inflammatory skin conditions, including infections, allergies or autoimmune diseases [2]. The skin, as a link between the internal organs and the external environment, is always in contact with various substances and agents, including microorganisms that colonize the skin [3]. In skin care products, probiotics can help restore the skin's natural balance by ensuring that it is functioning properly and is replenished with the necessary nutrients to stay protected from harmful factors and fight the signs of aging and environmental damage.…”

Modeling of probiotic gel shampoo recipes with vegetable extracts and marketing analysis of their market promotion

“…The task of cosmetics with probiotics is to create favorable conditions for the development of bacteria characteristic of the human microbiome [12,13]. In Ukraine, promising directions for the development of biotechnologies of «live» cosmetics using viable probiotic cells, as well as «probiotic» cosmetics using prebiotics and/or lysates of probiotic cultures of lactobacilli and bifidobacteria have been proposed [14]. Leading scientists point to the antimicrobial properties of cultures of lactobacilli and bifidobacteria, note their calming and anti-aging effects on the skin, hair, etc.…”