In the elderly, environmental stress and decreased cognitive function often cause depression. Depression that is not treated properly can cause an increase in the use of health facilities, a negative influence on the quality of life elderly, and can even cause death. Purpose of this research to know the relationship of cognitive function disorders with depression in the elderly at Posyandu Lansia Ikur Koto working area of the Puskesmas Ikur Koto, Padang. This type of research is correlative analytic with cross-sectional approach. Research has been conducted at posyandu lansia Ikur Koto in February 2019. The samples in this research was elderly who were recorded at the posyandu lansia Ikur Koto there were 51 elderly. Data analysis univariate presented in the form of a frequency distribution table and bivariate analysis using the spearman test using the SPSS program. Result of the 51 respondents, the majority of age was 60-74 years old (70,6%), the highest sex were women (94,1%), the highest education was elementary school (56,9%) ), the most marital status was married (52,9%), the highest health status (58,8%) did not suffer chronic diseases and most medical history does not use drugs (98%),most (72,5%) did not experiencing depression, most (37,3%) had mild cognitive function disorders and there were relationship between cognitive function disorders and depression in the elderly with a value p=0,007<0,05 and r=-0,373. Conclusion is there were significant relationship between cognitive function disorders and depression in the elderly at Posyandu Lansia Ikur Koto working area of the Puskesmas Ikur Koto, Padang.

The development of technology information in the 4.0 revolution era also affected to education. Higher education is demanded to develop curriculum based on digital literacy and technology literacy. The use of blended learning combines face-to-face methods with Google classroom in the Modul Pengantar Pembelajaran Kedokteran. The purpose of this study is to find out at the learning experiences of students using blended learning. Methods: This is descriptivestudy with cross sectional design. The study sample was first semester students at the Faculty of Medicine at Baiturrahmah University. Data collected through online questionnaire using Google form. Results: The number of respondents was 56 students. As many as 83.9% of students are familiar with the term e-learning or blended learning, 92.9% stated they did not experience difficulties when using google classroom,as many as 92.9% of students recommend google classroom as an effective media to e-learning. Conclusion: the benefits of blended learning can be felt by students, the media deliver learning resources and discussion with students and examine the results of student assignments quickly, and improve student discipline

<p><em>Peningkatan jumlah penduduk lansia menjadi tantangan sendiri. Pemenuhan fasilitas, sistem serta peran dari pemerintah dan masyarakat dengan tujuan meningkatkan kualitas hidup lansia.. Salah satu aspek yang terkait dengan proses penuaan adalah penurunan fungsi yang mencakup psikologis, sosiologis dan biologis. Salah satu perubahanan yaitu penurunan fungsi kognitif. Penuruan fungsi pada lansia juga menjadi faktor yang mempengaruhi tingkat kemandirian dari lansia. Tujuan penelitian ini adalah untuk menilai hubungan tingkat kemandirian dan gangguan kognitif pada lansia. Penelitian ini menggunakan desain cross-sectional dengan teknik pengumpulan sampel convenience-sampling. Sampel penelitian ini merupakan pasien prolanis. Pengumpulan data menggunakan kuesioner Moca-Ina versi Indonesia untuk menilai fungsi kognitif dan Indeks Barthel untuk menilai tingkat kemandirian. Untuk menilai keadaan sosiodemografi dinilai melalui wawancara. Hasil penelitian ini didapatkan hasil hubungan tingkat kemandirian dan gangguan kognitif pada lansia dengan hasil p=0.209. Untuk hasil tingkat kemandirian didapatkan hasil tingkat mandiri (92%), fungsi kognitif umumnya berada pada mild kognitif (76%). Dari penelitan ini disimpulkan hubungan tidak bermakna tingkat kemandirian dengan gangguan kognitif.</em></p>

Depression is a mental disorder that is often found in the elderly. Symptoms of depression in the elderly are often covered by physical symptoms. Depression in the elderly is influenced by various factors such as biology, psychology and social. Depression can further reduce the quality of life in the elderly. The study is a descriptive observational study and observed on 30 subjects were carried out on April 7, 2018. Aim of the study to determine the description of the Depression Rate in the Elderly in the Guguak Health Center Working Area District 50 Payakumbuh City. In the study, the subjects were 8 men (11.3%) and 22 women (73.3%). Theaverage subject age is 69.3. year. The highest level of education in the study subjects was high school (40%). Most patients did not have a history of other medical diseases (60%). In the study, 33.3% of the elderly were depressed. The levels of depression experienced were mild depression (23.3%) and major depression (10%).

A neneric drug is type of medication that has similiarities in the content of active ingredients with a paten drug, also in terms of usability and formulation. Other similiarities include the strength, dosage, quality, and safety of the  product  fot  the  wearer. Generic  drugs  are  actually  divided  into  2  different  types.  It  is  a  generic  drug branded and generic with a logo. Generic drugs also have the content of active substances as well as the same degree of effectiveness as patent drugs. Generic drugs themselves are actually drugs that have expired. Because of its condition, generic drugs can be sold at a much cheaper price range. This research aims to know how to level  the  public  knowledge  about  generic  drugs.  The  type  of  research  used  is  descriptive  using  the  data collection  method  in  the  form  of  a  questionnaire.  Respondents  in  this  study  numbered 60  people. The  Data obtained is processed and analyzed.  The Data obtained is then presented to the results of a community with low category knowledge of 56 people (93.3%) And the high category is 4 people (6.7%). It can be concluded that the community knowledge level about generic drugs is relatively low that is 93.3%. The results of this researchare expected to be information for the Puskesmas to be able to improve the socialization of generic drugs and also to health services, in order to increase

Penggunaan antipsikotik pada penderita skizofrenia memiliki efek blokade reseptor dopaminergik dan serotonergik yang menimbulkan penurunan gejala skizofrenia. Obat ini juga dapat menimbulkan efek samping berupa peningkatan berat badan yang meningkatkan risiko sindroma metabolik dan penyakit kardiovaskular. Penelitian ini bertujuan untuk mengidentifikasi keluhan peningkatan berat badan subjektif pada penderita skizofrenia yang mendapat terapi antipsikotik. Penelitian deskriptif ini menggunakan metode potong lintang dan mengikutsertakan 104 subjek penelitian yang terdiagnosis skizofrenia  dan  menjalani terapi rawat jalan di RS HB Saanin Padang. Subjek direkrut secara konsekutif sampling setelah memenuhi kriteria inklusi dan eksklusi. Penelitian ini memperoleh hasil bahwa subjek yang mendapat terapi obat atipikal, tipikal, dan kombinasi mengeluhkan peningkatan berat badan subjektif masing-masing sebesar 59,6% , 60,0% dan 53,2%.  Pada penelitian ini dapat disimpulkan bahwa terdapat keluhan peningkatan berat badan subjektif pada subjek penelitian yang memperoleh obat antipsikotik terutama golongan atipikal dan kombinasi.

<p class="Englishversionofabstract">Weight-gain is one of the antipsychotic side effects, and it can increase the risk factor of metabolic syndrome. Several studies relate it to increase leptin levels. This research was conducted to determine the profile of leptin levels in schizophrenic patients who were receiving antipsychotic therapy at Prof. DR. HB Saanin Mental Hospital. The research was conducted from November 2019 to January 2020 on schizophrenic patients who were taking antipsychotic drugs. This research was conducted on 50 samples by using consecutive sampling techniques. Data analysis using univariate are presented in geometric mean and CI 95%. Moreover, a Comparison of leptin levels between groups was performed by T-test and one-way ANOVA. The average leptin level from 50 samples of schizophrenic patients was 5.12µg/ml (CI 95%=3.32-7.90). The highest average leptin level is from the 46-55 year age group which is 11.32µg/ml (CI 95% =5.24 - 24.42), female is  13.29µg/ml (CI 95%=5.84-30.26), BMI ≥30kg/m2  is 12.84µg/ml (CI 95%=4.31-38.23), subjects with above-average waist circumference is 5.54µg/ml ( CI 95%=3.45-8.90), and the atypical group of drugs is 6.08µg/ml (IK 95%=3.41-10.84). Increasing levels of leptin occur in schizophrenic patients who were 46-55 y.o, female BMI ≥30kg/m2, above-average waist circumference, and receiving atypical antipsychotics.</p>

Antipsychotic-induced hyperprolactinemia disorder affects the morbidity and quality of life of the patient, and can lower the patient's adherence to taking antipsychotics, thereby lowering the therapeutic success rate. This study aims to figure out the incidence of hyperprolactinemia side effects in schizophrenia patients receiving antipsychotic therapy. This descriptive research was conducted at HB Saanin Psychiatric Hospital Padang in January-June 2018. The population in this study is all schizophrenia patients in the HB. Saanin Psychiatric Hospital Padang Year 2018 and involved participants as many as 100 people recruited in consecutive sampling. Data were analyzed using a descriptive statistical method. The results showed that more than half of the patients were 59 people (59.0%) hyperprolactinemia. Patients with gynecomastia amounted to 16 people (16%). Patients with galactorrhea amounted to 3 people (3%). Patients with sexual dysfunction amounted to 19 people (19%). Male patients amounted to 60 people, 21 people (35%) The sexual dysfunction of female patients amounted to 40 people, 26 people (65%) Menstrual cycle changes. More than half of the Schizophrenia patients receiving antipsychotic therapy in this study suffer symptoms of hyperprolactinemia in the manifestation of galactorrhea, gynecomastia, menstrual disorders, and sexual dysfunction.