Aim:The purpose of the present study was to determine the potential of Jatropha curcas latex in the cream formulation on CD68 immune expression (macrophages) during inflammatory phase wound healing process in mice skin.Materials and Methods:Amount of 12 two-months-old male mice were used between 30 and 40 g. To surgical procedures, wound skin incision was performed 2.0 cm in length until subcutaneous on the paravertebral of each animal. The treatment was carried under locally anesthetized with procaine cream. The mice were allotted into four groups of each, entire surface of each group wound covered by base cream control, sulfadiazine 0.1% cream, J. curcas latex cream 10% and, 15%, respectively. All experiments were performed twice a day for 3 days. The wound healing was assayed in stained histological sections in immunohistochemical of the wounds. CD68 expression was investigated under a microscope.Results:The results showed that the cream from the 10% and 15% latex of J. curcas revealed moderate immune reaction to CD68 on wound healing.Conclusion:We concluded that the latex cream of J. curcas possesses anti-inflammatory activity in wound healing process of mice skin.

Aim:The aim of this research was to determine the angiogenesis activity of Jatropha curcas latex in cream formulation on CD34 immune expression during wound healing phase in mice skin.Materials and Methods:Amount of 36 2-month-old male mice were used between 30 and 40 g. To surgical procedures, wound skin incision was performed 2.0 cm in length until subcutaneous on the paravertebral of each animal. The treatment was carried under locally anesthetized with procaine cream. All mice were divided into four groups, namely the base cream as control group (A), sulfadiazine 0.1% cream (B), Jatropha curcas latex cream 10% (C), and J. curcas latex cream 15% (D). All groups were treated entire surface of wound. All experiments were performed twice a day for 10 days. Experiments were terminated on days 3, 7, and 10, respectively. The wound healing was assayed in stained histological section in immunohistochemical of the wounds. The CD34 expression was investigated under a microscope.Results:The results showed that the cream from 10% and 15% latex J. curcas revealed moderate immune reaction to CD34 on days 3 and 7 in wound healing of mice skin.Conclusion:We concluded that the cream from 10% and 15% latex J. curcas has potential as angiogenesis activity in wound healing of mice skin.

The government efforts to maintain national energy stability program through the increase energy supply and saving must be supported by all levels of society. Several energy observers and experts stated that the contribution of the domestic or household sector in the activities of energy saving program is quite significant because the percentage of household customers are relatively high. This paper analyzes the potential of providing research data on the percentage of electricity savings in the domestic or household sectors towards saving electricity nationally. The results of the study show that electrical devices commonly used in households still have the potential to be saved. Electrical devices that are often used at households and have great saving potentials are air conditioners and refrigerators. If each household customer saves 30% of electricity consumption, then the national electricity supply that can be saved will be around 5,679 GW, equivalent to 83.3 trillion rupiah. The saving program resulted in savings of electricity consumption of around 6% of all household consumers or around 2.9% of total national electricity consumption.Keywords: electrical energy, savings, households ABSTRAKUpaya pemerintah dalam menjaga kestabilan energi nasional melalui program peningkatan pasokan dan penghematan energi harus didukung oleh seluruh lapisan masyarakat. Para pengamat dan pakar energi menyatakan bahwa kontribusi sektor domestik atau rumah tangga dalam program penghematan konsumsi energi listrik cukup signifikan karena persentase jumlah pelanggan rumah tangga yang relatif tinggi. Penelitian ini menganalisis tentang potensi persentase penghematan energi listrik sektor domestik atau rumah tangga terhadap  penghematan listrik secara nasional. Hasil penelitian menunjukkan bahwa piranti listrik yang biasa digunakan pada rumah tangga masih memiliki potensi untuk dilakukan penghematan. Piranti listrik yang sering digunakan pada rumah tangga dan memiliki potensi penghematan yang besar adalah alat pendingin ruangan (AC) dan kulkas. Bila setiap pelanggan rumah tangga melakukan penghematan konsumsi energi listriknya sebesar 30%, maka pasokan listrik nasional yang dapat dihemat adalah sekitar 5.679 GW atau setara dengan 83,3 Trilyun rupiah. Upaya ini menghasilkan penghematan konsumsi listrik sekitar 6% dari seluruh konsumen rumah tangga atau sekitar 2,9 % dari total konsumsi energi listrik nasional.Kata kunci: energi listrik, penghematan, rumah tangga

The objective of the present research was to find out the efficacy of Jatropha latex cream in the epithelialization phase of wound healing in mice skin. A total of 9 male mice aged 2-3 months old and the bodyweight of 25-40 g were divided into three treatment groups. Group A was given basic cream, group B was given Jatropha latex cream (10%), and group C was given sulfadiazine. The 2 cm incision wound was made in the paravertebral area. Wound therapy was carried out twice a day for 7 days. All quantitative data were measured using ANOVA then followed by the Duncan test. The number of angiogenesis on A, B, and C was 4.67±1.20; 12.78±2.52; and 11.33±2.33, while a number of fibroblasts were 179.56±12.69; 90.56±8.23; and 99.11±7.04, respectively. The average deposition of collagen was 1.46±0.12; 1.89±0.10; and 1.74±0.06, respectively. The statistical test showed that the number of angiogenesis, fibroblast, and deposition of collagen on group B was significantly different (P<0.05) compared to group A and showed no significant difference compared to group C (P>0.05). In conclusion, Jatropha latex cream (10%) able to accelerate the epithelialization phase of wound healing in mice skin.

ABSTRAKPenelitian ini bertujuan mengetahui pengaruh pemberian kacang panjang (Vigna unguiculata) terhadap kadar glukosa darah mencit (Mus musculus) yang diinduksi aloksan. Dalam penelitian ini digunakan 12 ekor mencit dengan berat 25-40 g yang secara klinis dinyatakan sehat. Mencit dibagi menjadi empat kelompok perlakuan, masing-masing kelompok perlakuan terdiri atas tiga ekor mencit. Kelompok K0 adalah kelompok kontrol negatif, hanya diberi akuades. Kelompok K1, K2, dan K3 adalah kelompok yang diinduksi aloksan masing-masing 0,5 ml. Kelompok K1 adalah kontrol positif. Kelompok K2 diberikan 100 g kacang panjang yang dicampur dengan akuades 50 ml. Kelompok K3 diberikan 100 g kacang panjang yang dicampur dengan 100 ml akuades. Kacang panjang diberikan 0,5 ml secara oral pada pagi dan sore hari selama tujuh hari. Pada hari ke-8 dilakukan pemeriksaan kadar glukosa darah. Rata-rata kadar glukosa darah setelah perlakuan K0; K1; K2; dan K3 masing-masing adalah 142,00±23,39; 167,00±10,54; 122,67±12,50; dan 154,67±16,26 mg/dl (P>0,05). Dapat disimpulkan bahwa pemberian kacang panjang selama tujuh hari tidak menurunkan kadar glukosa darah mencit yang diinduksi aloksan. ____________________________________________________________________________________________________________________ Kata kunci: aloksan, glukosa darah, kacang panjang ABSTRACT The aim of this research was to find out the effect of long bean (Vigna unguiculata) on level of blood glucose on mice (Mus musculus

The purpose of this study is to analyze the role of dividend policy in mediating the effect of earnings per share, debt equity to ratio and price book value on stock prices. The sample used is a manufacturing company listed on the Indonesian stock exchange with complete financial statements for the 2015-2020 period. Data were analyzed using path analysis method using SPSS version 25 software. The results of this study indicate that earnings per share have no effect on dividend policy. Debt equity to ratio has no effect on the company's dividend policy. Price book value has no effect on the company's dividend policy. Dividend performance has no effect on stock prices. Earning per share has an effect on stock prices. Debt equity to ratio has an effect on stock prices. Price book value has an effect on stock prices. Dividend policy is not successful in mediating the effect of earnings per share on stock prices. Dividend policy also failed to mediate the effect of debt euqity to ratio on stock prices. Furthermore, the dividend policy also failed to mediate the effect of price book value on stock prices

This study was conducted to determine the best level of noni fruit extract (Morinda citrifolia L) addition into citrate-yolk extender on the motility of boer goats spermatozoa preserved at 5℃. Semen was collected using artificial vagina once a week from 1 healthy male aged ±7 years,. The treatments were citrateyolk administrated by noni fruit extracts (P0: 0 g, P1: 2 g/100 ml, P2: 4 g/100 ml, P3: 6 g/100 ml, P4: 8 g/100 ml) and stored at 5℃. The parameters were motility spermatozoa percentage. Observations were made at 2, 24, 48, 72 96 hours after refrigeration. The data obtained was analyzed with split plot analysis of variance (ANOVA) follo wed by Duncan test. The average percentage of sperm motility after refrigated for 96 hours in the groups P0; P1; P2; P3; and P4 respectively was 24,20±0,83%; 34,40±4,61%; 40,20±5,71%; 14,64±21,63%; and 9,54±21,33%. The results showed that giving of noni fruit extract significantly affected (p<0,05) on the percentage of motility spermatozoa of boer goat after refrigeration. It was concluded that the administration of 4 g/100 ml noni fruit extract in citrateyolk after stored at 5℃ resulted a greater sperm motility for up to 96 hours.

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