No abstract

The body weight or body weight/height ratio exhibits a positive linear correlation to hair zinc (Zn) concentration which is more strongly positive in men than in women. The obese of both sexes possess higher Zn concentrations in their hair than those with normal body weight/height. The degree of obesity increases with the increase in the hair Zn concentration.

The concentration of copper (Cu) and zinc (Zn) in hair and urine were studied in young nonpregnant healthy women whose both parents were diagnosed for noninsulin-dependent diabetes mellitus (NIDDM descendants) and were compared with those of young healthy nonpregnant females with no family history of NIDDM or hypertension (non-NIDDM descendants) and NIDDM patients. The concentration of Zn in hair in NIDDM descendants was significantly higher than that of non-NIDDM descendants (p < 0.001) and insignificantly higher than that of NIDDM patients. The hair Cu concentrations in NIDDM descendant and patients were significantly lower than that of non-NIDDM descendants (p < 0.001). Hyperzincuria was detected in some NIDDM patients and hypocuperuria in all NIDDM descendants and patients. The data suggest that the young healthy NIDDM descendants possess high-Zn and low-Cu reserves in their bodies, and the observed perturbation appears to be associated with Cu-Zn antagonism.

INTRODUCTIONThe use of USG (ultrasound) guided peripheral nerve block is a relatively new technique that is rapidly gaining popularity over more traditional techniques of peripheral nerve stimulators and parasthesia.1 Use of ultrasound not only avoids the injury to the nerves associated with blind paraesthesia technique but also decreases the total dose ABSTRACT Background: Ultrasound guided brachial plexus block is the preferred technique for surgeries on upper limb. Adjuvants are usually added to peripheral nerve blocks to increase their analgesic efficiency and duration. We compared analgesic effects of dexmedetomidine 1mcg/kg and clonidine 1mcg/kg as adjuvant to a low volume of bupivacaine in USG guided supraclavicular brachial plexus block. Methods: A prospective, randomized controlled, double blind study planned after permission from institutional ethics committee. Sixty ASA grade I, II patients, 18-60 years undergoing upper limb orthopedic surgery included. Group 1 (Control group) received 20 ml of 0.25% bupivacaine. Group 2 (Dexmedetomidine group) received 20ml of bupivacaine + dexmedetomidine (10 ml of 0.5% bupivacaine + 1µg/kg of dexmedetomidine, diluted with 0.9% NS to 20 ml) Group 3 (Clonidine group) received 20 ml of 0.25 bupivacaine + clonidine (10ml of 0.5% bupivacaine+1µ g/kg of clonidine, diluted with 0.9% NS to 20 ml) in USG guided supraclavicular brachial plexus block. Continuous variables analyzed with analysis of variance or Kruskal-Wallis test and categorical variables with Fisher's exact test. Results: Pain free period was 864.90±357.16 minutes: dexmedetomidine group; 584.59±172.38 minutes: clonidine group, 431.78±138.40 minutes: control group with p< 0.001. VRS (verbal rating score) was significantly higher in control group as compared to dexmedetomidine at 4 hours but the pain scores were comparable between all the groups after 8 hours of block. Conclusions: Dexmedetomidine as an adjuvant to bupivacaine provides prolonged anaesthesia, better pain relief in early postoperative period with haemodynamically stable, calm patients compared to clonidine and control group.

No abstract

Objectives:The objective of the study is to assess the skeletal, dental, and soft-tissue effects of PowerScope fixed functional appliance in Class II malocclusion. Materials and Methods: Fifteen late adolescent Class II subjects (CVMI Stages 5 and 6) were treated with fixed mechanotherapy and PowerScope fixed functional appliance. Student t-test was used to compare the cephalometric changes produced before insertion of appliance (T1) and 6 months after the treatment with this appliance (T2). Results: Maxillomandibular relationship improved with significant lengthening of the mandible. There was retroclination of maxillary incisors, proclination of mandibular incisors, extrusion, and sagittal displacement of mandibular molars and clockwise rotation of occlusal plane. Conclusion: PowerScope is effective in correcting Class II malocclusion with a combination of dentoalveolar (primarily) and skeletal changes. abstRactThis is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.

No abstract

Introduction: The aim of the study was to determine the effect of different prophylaxis pastes on shear bond strength of orthodontic brackets bonded with Self-Etch Primer (SEP). Methods: Two hundred human premolars were divided into 4 equal groups. In Group 1 (control), no prophylaxis was done prior to bonding with SEP. In Groups 2-4 different prophylaxis pastes, that is, pumice, nonfluoridated and fluoridated pastes were used respectively. After bonding, the samples were debonded using a universal testing machine at a cross head speed of 0.5 mm/min. Results: The shear bond strength (MPa) for Group 1-4 was 5.99, 7.51, 7.57, and 7.71, respectively. Conclusions: The result shows that the shear bond strength of brackets bonded with SEP without prior prophylaxis produces statistically significant lower bond strength as compared to brackets which were bonded with prior prophylaxis treatments. The shear bond strengths of orthodontic brackets bonded with SEP with prior prophylaxis with various prophylaxis pastes were not statistically different from each other. The use of fluoridated prophylaxis pastes did not adversely affect bond strength of orthodontic brackets bonded with SEP.